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Protein
Submitted name:

T-cell leukemia homeobox protein 1

Gene

Tlx1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi204 – 263HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotationImported

Names & Taxonomyi

Protein namesi
Submitted name:
T-cell leukemia homeobox protein 1Imported
Submitted name:
T-cell leukemia, homeobox 1Imported
Submitted name:
Transcription factorImported
Gene namesi
Name:Tlx1Imported
Synonyms:Hox11Imported
ORF Names:mCG_16921Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 19

Organism-specific databases

MGIiMGI:98769. Tlx1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000025215.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000026236.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini202 – 262HomeoboxInterPro annotationAdd BLAST61

Keywords - Domaini

HomeoboxPROSITE-ProRule annotationSAAS annotationImported

Phylogenomic databases

eggNOGiKOG0488. Eukaryota.
ENOG411188D. LUCA.
GeneTreeiENSGT00870000136367.
HOGENOMiHOG000116280.
HOVERGENiHBG036206.
KOiK09340.
OMAiGEYGLGC.
OrthoDBiEOG091G0RNV.
TreeFamiTF325347.

Family and domain databases

CDDicd00086. homeodomain. 1 hit.
InterProiView protein in InterPro
IPR009057. Homeobox-like.
IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR020479. Homeobox_metazoa.
PfamiView protein in Pfam
PF00046. Homeobox. 1 hit.
PRINTSiPR00024. HOMEOBOX.
SMARTiView protein in SMART
SM00389. HOX. 1 hit.
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiView protein in PROSITE
PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9QX99-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEHLGPHHLH PGHAEPISFG IDQILNSPDQ GGCMGPASRL QDGDYGLGCL
60 70 80 90 100
VGGAYTYGGG GSAAGAGAGG TGAYGAGGPG GPGGPAGGGG GACSMGPLPG
110 120 130 140 150
SYNVNMALAG GPGPGGGGGG GGAGGAGALS AAGVIRVPAH RPLAGAVAHP
160 170 180 190 200
QPLATGLPTV PSVPAVPGVN NLTGLTFPWM ESNRRYTKDR FTGHPYQNRT
210 220 230 240 250
PPKKKKPRTS FTRLQICELE KRFHRQKYLA SAERAALAKA LKMTDAQVKT
260 270 280 290 300
WFQNRRTKWR RQTAEEREAE RQQANRILLQ LQQEAFQKSL AQPLPADPLC
310 320 330
VHNSSLFALQ NLQPWSDDST KITSVTSVAS ACE
Length:333
Mass (Da):34,396
Last modified:May 1, 2000 - v1
Checksum:iE1ABB150A87D4171
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC170878 Genomic DNA. No translation available.
BC018246 mRNA. Translation: AAH18246.1.
AJ251787 Genomic DNA. Translation: CAB63267.1.
CH466534 Genomic DNA. Translation: EDL41949.1.
RefSeqiNP_068701.1. NM_021901.3.
UniGeneiMm.391203.

Genome annotation databases

EnsembliENSMUST00000026236; ENSMUSP00000026236; ENSMUSG00000025215.
GeneIDi21908.
KEGGimmu:21908.
UCSCiuc008hqu.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiQ9QX99_MOUSE
AccessioniPrimary (citable) accession number: Q9QX99
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: September 27, 2017
This is version 133 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported