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Q9QX47

- SON_MOUSE

UniProt

Q9QX47 - SON_MOUSE

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Protein
Protein SON
Gene
Son, Nrebp
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

RNA-binding protein that acts as a mRNA splicing cofactor by promoting efficient splicing of transcripts that possess weak splice sites. Specifically promotes splicing of many cell-cycle and DNA-repair transcripts that possess weak splice sites, such as TUBG1, KATNB1, TUBGCP2, AURKB, PCNT, AKT1, RAD23A, and FANCG. Probably acts by facilitating the interaction between Serine/arginine-rich proteins such as SRSF2 and the RNA polymerase II. Also binds to DNA; binds to the consensus DNA sequence: 5'-GA[GT]AN[CG][AG]CC-3' By similarity. May also regulate the ghrelin signaling in hypothalamic neuron by acting as a negative regulator of GHSR expression.1 Publication

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. RNA binding Source: UniProtKB
  3. RS domain binding Source: MGI
  4. protein binding Source: MGI

GO - Biological processi

  1. RNA splicing Source: UniProtKB-KW
  2. cytokinesis Source: UniProtKB
  3. mRNA processing Source: UniProtKB
  4. microtubule cytoskeleton organization Source: UniProtKB
  5. negative regulation of apoptotic process Source: Ensembl
  6. regulation of RNA splicing Source: UniProtKB
  7. regulation of cell cycle Source: UniProtKB
  8. regulation of transcription, DNA-templated Source: UniProtKB-KW
  9. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Cell cycle, mRNA processing, mRNA splicing, Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Protein SON
Alternative name(s):
Negative regulatory element-binding protein
Short name:
NRE-binding protein
Gene namesi
Name:Son
Synonyms:Nrebp
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 16

Organism-specific databases

MGIiMGI:98353. Son.

Subcellular locationi

Nucleus speckle By similarity
Note: Colocalizes with the pre-mRNA splicing factor SRSF2 By similarity.1 Publication

GO - Cellular componenti

  1. nuclear speck Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed By similarity
Chaini2 – 24442443Protein SON
PRO_0000072038Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylalanine By similarity
Modified residuei16 – 161N6-acetyllysine By similarity
Modified residuei94 – 941Phosphoserine By similarity
Modified residuei142 – 1421Phosphoserine By similarity
Modified residuei150 – 1501Phosphoserine By similarity
Modified residuei152 – 1521Phosphoserine By similarity
Modified residuei158 – 1581Phosphoserine By similarity
Modified residuei284 – 2841N6-acetyllysine By similarity
Modified residuei1723 – 17231Phosphoserine2 Publications
Modified residuei1794 – 17941Phosphoserine By similarity
Modified residuei1808 – 18081Phosphoserine By similarity
Modified residuei1973 – 19731Phosphoserine By similarity
Modified residuei1975 – 19751Phosphoserine By similarity
Modified residuei2027 – 20271Phosphoserine By similarity
Modified residuei2029 – 20291Phosphoserine By similarity
Modified residuei2031 – 20311Phosphoserine By similarity
Modified residuei2073 – 20731N6-acetyllysine1 Publication
Modified residuei2181 – 21811Phosphothreonine By similarity

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

MaxQBiQ9QX47.
PaxDbiQ9QX47.
PRIDEiQ9QX47.

PTM databases

PhosphoSiteiQ9QX47.

Expressioni

Tissue specificityi

Widely expressed. Highly expressed in brain, heart, spleen, liver, skeletal muscle, kidney and testis.1 Publication

Inductioni

By leptin. Highly expressed in hypothalamus following leptin injection.1 Publication

Gene expression databases

ArrayExpressiQ9QX47.
BgeeiQ9QX47.
CleanExiMM_SON.
GenevestigatoriQ9QX47.

Interactioni

Subunit structurei

Interacts with SRSF2. Associates with the spliceosome By similarity.

Protein-protein interaction databases

BioGridi203390. 1 interaction.
DIPiDIP-49510N.
IntActiQ9QX47. 6 interactions.
MINTiMINT-1713045.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati1001 – 100661-1
Repeati1009 – 101461-2
Repeati1016 – 102161-3
Repeati1025 – 103061-4
Repeati1033 – 103861-5
Repeati1041 – 104661-6
Repeati1050 – 105561-7
Repeati1058 – 106361-8
Repeati1066 – 107161-9
Repeati1075 – 108061-10
Repeati1084 – 108961-11
Repeati1095 – 110061-12
Repeati1106 – 111161-13
Repeati1115 – 112061-14
Repeati1950 – 195672-1
Repeati1959 – 1977193-1
Add
BLAST
Repeati1978 – 198472-2
Repeati1985 – 199172-3
Repeati1992 – 199872-4
Repeati1999 – 200572-5
Repeati2006 – 201272-6
Repeati2013 – 201972-7; approximate
Repeati2020 – 2030113-2; approximate
Add
BLAST
Domaini2323 – 236947G-patch
Add
BLAST
Domaini2389 – 244456DRBM
Add
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni721 – 85013013 X 10 AA tandem repeats of L-A-[ST]-[NSG]-[TS]-MDSQM
Add
BLAST
Regioni907 – 9837711 X 7 AA tandem repeats of [DR]-P-Y-R-[LI][AG][QHP]
Add
BLAST
Regioni1001 – 112012014 X 6 AA repeats of [ED]-R-S-M-M-S
Add
BLAST
Regioni1141 – 1173333 X 11 AA tandem repats of P-P-L-P-P-E-E-P-P-[TME]-[MTG]
Add
BLAST
Regioni1950 – 2019707 X 7 AA repeats of P-S-R-R-S-R-[TS]
Add
BLAST
Regioni1959 – 2030722 X 19 AA repeats of P-S-R-R-R-R-S-R-S-V-V-R-R-R-S-F-S-I-S
Add
BLAST
Regioni2031 – 2057273 X tandem repeats of [ST]-P-[VLI]-R-[RL]-[RK]-[RF]-S-R
Add
BLAST

Domaini

Sequence similaritiesi

Contains 1 G-patch domain.

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiNOG84537.
GeneTreeiENSGT00730000111141.
HOVERGENiHBG023160.
InParanoidiQ811G3.
TreeFamiTF330344.

Family and domain databases

Gene3Di3.30.160.20. 1 hit.
InterProiIPR014720. dsRNA-bd_dom.
IPR000467. G_patch_dom.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF01585. G-patch. 1 hit.
[Graphical view]
SMARTiSM00443. G_patch. 1 hit.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiPS50137. DS_RBD. 1 hit.
PS50174. G_PATCH. 1 hit.
[Graphical view]

Sequences (4)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 4 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q9QX47-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MAADIEQVFR SFVVSKFREI QQELSSGRSE GQLNGETNPP IEGNQAGDTA     50
ASARSLPNEE IVQKIEEVLS GVLDTELRYK PDLKEASRKS RCVSVQTDPT 100
DEVPTKKSKK HKKHKNKKKK KKKEKEKKYK RQPEESESKL KSHHDGNLES 150
DSFLKFDSEP SAAALEHPVR AFGLSEASET ALVLEPPVVS MEVQESHVLE 200
TLKPATKAAE LSVVSTSVIS EQSEQPMPGM LEPSMTKILD SFTAAPVPMS 250
TAALKSPEPV VTMSVEYQKS VLKSLETMPP ETSKTTLVEL PIAKVVEPSE 300
TLTIVSETPT EVHPEPSPST MDFPESSTTD VQRLPEQPVE APSEIADSSM 350
TRPQESLELP KTTAVELQES TVASALELPG PPATSILELQ GPPVTPVPEL 400
PGPSATPVPE LSGPLSTPVP ELPGPPATVV PELPGPSVTP VPQLSQELPG 450
PPAPSMGLEP PQEVPEPPVM AQELSGVPAV SAAIELTGQP AVTVAMELTE 500
QPVTTTEFEQ PVAMTTVEHP GHPEVTTATG LLGQPEAAMV LELPGQPVAT 550
TALELSGQPS VTGVPELSGL PSATRALELS GQSVATGALE LPGQLMATGA 600
LEFSGQSGAA GALELLGQPL ATGVLELPGQ PGAPELPGQP VATVALEISV 650
QSVVTTSELS TMTVSQSLEV PSTTALESYN TVAQELPTTL VGETSVTVGV 700
DPLMAQESHM LASNTMETHM LASNTMDSQM LASNTMDSQM LASNTMDSQM 750
LASSTMDSQM LASSTMDSQM LATSTMDSQM LATSSMDSQM LATSSMDSQM 800
LATSSMDSQM LATSSMDSQM LATSSMDSQM LATSSMDSQM LATSSMDSQM 850
LATSSMDSQM LASGAMDSQM LASGTMDAQM LASGTMDAQM LASSTQDSAM 900
MGSKSPDPYR LAQDPYRLAQ DPYRLGHDPY RLGHDAYRLG QDPYRLGHDP 950
YRLTPDPYRV SPRPYRIAPR SYRIAPRPYR LAPRPLMLAS RRSMMMSYAA 1000
ERSMMSSYER SMMSYERSMM SPMAERSMMS AYERSMMSAY ERSMMSPMAE 1050
RSMMSAYERS MMSAYERSMM SPMADRSMMS MGADRSMMSS YSAADRSMMS 1100
SYSAADRSMM SSYTDRSMMS MAADSYTDSY TDSYTEAYMV PPLPPEEPPT 1150
MPPLPPEEPP MTPPLPPEEP PEGPALSTEQ SALTADNTWS TEVTLSTGES 1200
LSQPEPPVSQ SEISEPMAVP ANYSMSESET SMLASEAVMT VPEPAREPES 1250
SVTSAPVESA VVAEHEMVPE RPMTYMVSET TMSVEPAVLT SEASVISETS 1300
ETYDSMRPSG HAISEVTMSL LEPAVTISQP AENSLELPSM TVPAPSTMTT 1350
TESPVVAVTE IPPVAVPEPP IMAVPELPTM AVVKTPAVAV PEPLVAAPEP 1400
PTMATPELCS LSVSEPPVAV SELPALADPE HAITAVSGVS SLEPSVPILE 1450
PAVSVLQPVM IVSEPSVPVQ EPTVAVSEPA VIVSEHTQIT SPEMAVESSP 1500
VIVDSSVMSS QIMKGMNLLG GDENLGPEVG MQETLLHPGE EPRDGGHLKS 1550
DLYENEYDRN ADLTVNSHLI VKDAEHNTVC ATTVGPVGEA SEEKILPISE 1600
TKEITELATC AAVSEADIGR SLSSQLALEL DTVGTSKGFE FVTASALISE 1650
SKYDVEVSVT TQDTEHDMVI STSPSGGSEA DIEGPLPAKD IHLDLPSTNF 1700
VCKDVEDSLP IKESAQAVAV ALSPKESSED TEVPLPNKEI VPESGYSASI 1750
DEINEADLVR PLLPKDMERL TSLRAGIEGP LLASEVERDK SAASPVVISI 1800
PERASESSSE EKDDYEIFVK VKDTHEKSKK NKNRDKGEKE KKRDSSLRSR 1850
SKRSKSSEHK SRKRTSESRS RARKRSSKSK SHRSQTRSRS RSRRRRRSSR 1900
SRSKSRGRRS VSKEKRKRSP KHRSKSRERK RKRSSSRDNR KAARARSRTP 1950
SRRSRSHTPS RRRRSRSVGR RRSFSISPSR RSRTPSRRSR TPSRRSRTPS 2000
RRSRTPSRRS RTPSRRRRSR SAVRRRSFSI SPVRLRRSRT PLRRRFSRSP 2050
IRRKRSRSSE RGRSPKRLTD LDKAQLLEIA KANAAAMCAK AGVPLPPNLK 2100
PAPPPTIEEK VAKKSGGATI EELTEKCKQI AQSKEDDDVI VNKPHVSDEE 2150
EEEPPFYHHP FKLSEPKPIF FNLNIAAAKP TPPKSQVTLT KEFPVSSGSQ 2200
HRKKEADSVY GEWVPVEKNG EESKDDDNVF SSSLPSEPVD ISTAMSERAL 2250
AQKRLSENAF DLEAMSMLNR AQERIDAWAQ LNSIPGQFTG STGVQVLTQE 2300
QLANTGAQAW IKKDQFLRAA PVTGGMGAVL MRKMGWREGE GLGKNKEGNK 2350
EPILVDFKTD RKGLVAVGER AQKRSGNFSA AMKDLSGKHP VSALMEICNK 2400
RRWQPPEFLL VHDSGPDHRK HFLFRVLRNG SPYQPNCMFF LNRY 2444
Length:2,444
Mass (Da):265,651
Last modified:June 28, 2011 - v2
Checksum:iE873ADCB51B7123B
GO
Isoform 2 (identifier: Q9QX47-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     2126-2126: K → F
     2127-2444: Missing.

Show »
Length:2,126
Mass (Da):230,022
Checksum:iD977785966267327
GO
Isoform 3 (identifier: Q9QX47-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     776-815: Missing.

Show »
Length:2,404
Mass (Da):261,443
Checksum:i6163EBD3D5E8FB95
GO
Isoform 4 (identifier: Q9QX47-4) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     776-815: Missing.
     2238-2444: PVDISTAMSE...PNCMFFLNRY → GRVKRQGRVK...SRLYSSRFWW

Show »
Length:2,281
Mass (Da):247,971
Checksum:i10ABA0C4E10F6C03
GO

Sequence cautioni

The sequence AAH46419.1 differs from that shown. Reason: Contaminating sequence. Potential poly-A sequence.

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei776 – 81540Missing in isoform 3 and isoform 4.
VSP_041557Add
BLAST
Alternative sequencei2126 – 21261K → F in isoform 2.
VSP_004416
Alternative sequencei2127 – 2444318Missing in isoform 2.
VSP_004417Add
BLAST
Alternative sequencei2238 – 2444207PVDIS…FLNRY → GRVKRQGRVKRQMKQPAASH LTVTRCNSLCGTKPQSEKHR IAEKSVITSLPNIGPSMHLW EGSPRYNYLASRFASRLYSS RFWW in isoform 4.
VSP_041558Add
BLAST

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti857 – 8571D → E in AAF23120. 1 Publication
Sequence conflicti857 – 8571D → E in AAF23121. 1 Publication
Sequence conflicti857 – 8571D → E in BAJ40169. 1 Publication
Sequence conflicti1333 – 13331N → D in AAF23120. 1 Publication
Sequence conflicti1333 – 13331N → D in AAF23121. 1 Publication
Sequence conflicti1734 – 17341P → L in AAF23120. 1 Publication
Sequence conflicti1734 – 17341P → L in AAF23121. 1 Publication
Sequence conflicti1966 – 19661R → I in AAF23120. 1 Publication
Sequence conflicti1966 – 19661R → I in AAF23121. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF193606
, AF193595, AF193596, AF193597, AF193598, AF193599, AF193600, AF193601, AF193602, AF193603, AF193604, AF193605 Genomic DNA. Translation: AAF23120.1.
AF193607 mRNA. Translation: AAF23121.1.
AB546195 mRNA. Translation: BAJ40169.1.
AC131691 Genomic DNA. No translation available.
BC046419 mRNA. Translation: AAH46419.1. Sequence problems.
AK019312 mRNA. Translation: BAB31659.1.
AK019081 mRNA. Translation: BAB31536.1.
AK008478 mRNA. Translation: BAB25691.1.
AK008256 mRNA. Translation: BAB25562.1.
CCDSiCCDS37399.1. [Q9QX47-1]
CCDS37400.1. [Q9QX47-2]
RefSeqiNP_849211.3. NM_178880.4. [Q9QX47-1]
UniGeneiMm.46401.
Mm.491378.

Genome annotation databases

EnsembliENSMUST00000114036; ENSMUSP00000109670; ENSMUSG00000022961. [Q9QX47-2]
ENSMUST00000114037; ENSMUSP00000109671; ENSMUSG00000022961. [Q9QX47-1]
GeneIDi20658.
KEGGimmu:20658.
UCSCiuc007zxy.1. mouse. [Q9QX47-2]
uc007zxz.1. mouse. [Q9QX47-1]
uc012aii.1. mouse. [Q9QX47-4]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF193606
, AF193595 , AF193596 , AF193597 , AF193598 , AF193599 , AF193600 , AF193601 , AF193602 , AF193603 , AF193604 , AF193605 Genomic DNA. Translation: AAF23120.1 .
AF193607 mRNA. Translation: AAF23121.1 .
AB546195 mRNA. Translation: BAJ40169.1 .
AC131691 Genomic DNA. No translation available.
BC046419 mRNA. Translation: AAH46419.1 . Sequence problems.
AK019312 mRNA. Translation: BAB31659.1 .
AK019081 mRNA. Translation: BAB31536.1 .
AK008478 mRNA. Translation: BAB25691.1 .
AK008256 mRNA. Translation: BAB25562.1 .
CCDSi CCDS37399.1. [Q9QX47-1 ]
CCDS37400.1. [Q9QX47-2 ]
RefSeqi NP_849211.3. NM_178880.4. [Q9QX47-1 ]
UniGenei Mm.46401.
Mm.491378.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 203390. 1 interaction.
DIPi DIP-49510N.
IntActi Q9QX47. 6 interactions.
MINTi MINT-1713045.

PTM databases

PhosphoSitei Q9QX47.

Proteomic databases

MaxQBi Q9QX47.
PaxDbi Q9QX47.
PRIDEi Q9QX47.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000114036 ; ENSMUSP00000109670 ; ENSMUSG00000022961 . [Q9QX47-2 ]
ENSMUST00000114037 ; ENSMUSP00000109671 ; ENSMUSG00000022961 . [Q9QX47-1 ]
GeneIDi 20658.
KEGGi mmu:20658.
UCSCi uc007zxy.1. mouse. [Q9QX47-2 ]
uc007zxz.1. mouse. [Q9QX47-1 ]
uc012aii.1. mouse. [Q9QX47-4 ]

Organism-specific databases

CTDi 6651.
MGIi MGI:98353. Son.

Phylogenomic databases

eggNOGi NOG84537.
GeneTreei ENSGT00730000111141.
HOVERGENi HBG023160.
InParanoidi Q811G3.
TreeFami TF330344.

Miscellaneous databases

ChiTaRSi SON. mouse.
NextBioi 299093.
PROi Q9QX47.
SOURCEi Search...

Gene expression databases

ArrayExpressi Q9QX47.
Bgeei Q9QX47.
CleanExi MM_SON.
Genevestigatori Q9QX47.

Family and domain databases

Gene3Di 3.30.160.20. 1 hit.
InterProi IPR014720. dsRNA-bd_dom.
IPR000467. G_patch_dom.
IPR017986. WD40_repeat_dom.
[Graphical view ]
Pfami PF01585. G-patch. 1 hit.
[Graphical view ]
SMARTi SM00443. G_patch. 1 hit.
[Graphical view ]
SUPFAMi SSF50978. SSF50978. 1 hit.
PROSITEi PS50137. DS_RBD. 1 hit.
PS50174. G_PATCH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Organization and conservation of the GART/SON/DONSON locus in mouse and human genomes."
    Wynn S.L., Fisher R.A., Pagel C., Price M., Liu Q.Y., Khan I.M., Zammit P., Dadrah K., Mazrani W., Kessling A., Lee J.S., Buluwela L.
    Genomics 68:57-62(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORMS 2 AND 3), NUCLEOTIDE SEQUENCE [MRNA] OF 1-2125 (ISOFORM 3), SUBCELLULAR LOCATION.
    Strain: 129/Sv.
  2. "Regulation of ghrelin signaling by a leptin-induced gene, negative regulatory element-binding protein, in the hypothalamic neurons."
    Komori T., Doi A., Furuta H., Wakao H., Nakao N., Nakazato M., Nanjo K., Senba E., Morikawa Y.
    J. Biol. Chem. 285:37884-37894(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 4), FUNCTION, TISSUE SPECIFICITY, INDUCTION.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-1827 (ISOFORM 1).
    Strain: FVB/N.
    Tissue: Kidney.
  5. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-116.
    Strain: C57BL/6J.
    Tissue: Hippocampus, Small intestine and Tongue.
  6. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1723, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Liver.
  7. "The phagosomal proteome in interferon-gamma-activated macrophages."
    Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.
    Immunity 30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1723, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  8. "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
    Park J., Chen Y., Tishkoff D.X., Peng C., Tan M., Dai L., Xie Z., Zhang Y., Zwaans B.M., Skinner M.E., Lombard D.B., Zhao Y.
    Mol. Cell 50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-2073, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Embryonic fibroblast.

Entry informationi

Entry nameiSON_MOUSE
AccessioniPrimary (citable) accession number: Q9QX47
Secondary accession number(s): E3WC91
, E9PXW2, E9Q3H8, E9Q3I0, E9Q6M4, E9Q7G2, E9QAR8, E9QMT0, Q811G3, Q9CQ12, Q9CQK6, Q9QXP5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 23, 2002
Last sequence update: June 28, 2011
Last modified: July 9, 2014
This is version 117 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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