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Q9QX47

- SON_MOUSE

UniProt

Q9QX47 - SON_MOUSE

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Protein

Protein SON

Gene

Son

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Functioni

RNA-binding protein that acts as a mRNA splicing cofactor by promoting efficient splicing of transcripts that possess weak splice sites. Specifically promotes splicing of many cell-cycle and DNA-repair transcripts that possess weak splice sites, such as TUBG1, KATNB1, TUBGCP2, AURKB, PCNT, AKT1, RAD23A, and FANCG. Probably acts by facilitating the interaction between Serine/arginine-rich proteins such as SRSF2 and the RNA polymerase II. Also binds to DNA; binds to the consensus DNA sequence: 5'-GA[GT]AN[CG][AG]CC-3' (By similarity). May also regulate the ghrelin signaling in hypothalamic neuron by acting as a negative regulator of GHSR expression.By similarity1 Publication

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. poly(A) RNA binding Source: Ensembl
  3. RNA binding Source: UniProtKB
  4. RS domain binding Source: MGI

GO - Biological processi

  1. cytokinesis Source: UniProtKB
  2. microtubule cytoskeleton organization Source: UniProtKB
  3. mRNA processing Source: UniProtKB
  4. negative regulation of apoptotic process Source: Ensembl
  5. regulation of cell cycle Source: UniProtKB
  6. regulation of RNA splicing Source: UniProtKB
  7. regulation of transcription, DNA-templated Source: UniProtKB-KW
  8. RNA splicing Source: UniProtKB-KW
  9. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Cell cycle, mRNA processing, mRNA splicing, Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Protein SON
Alternative name(s):
Negative regulatory element-binding protein
Short name:
NRE-binding protein
Gene namesi
Name:Son
Synonyms:Nrebp
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 16

Organism-specific databases

MGIiMGI:98353. Son.

Subcellular locationi

Nucleus speckle By similarity
Note: Colocalizes with the pre-mRNA splicing factor SRSF2.By similarity

GO - Cellular componenti

  1. nuclear speck Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11RemovedBy similarity
Chaini2 – 24442443Protein SONPRO_0000072038Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylalanineBy similarity
Modified residuei16 – 161N6-acetyllysineBy similarity
Modified residuei94 – 941PhosphoserineBy similarity
Modified residuei142 – 1421PhosphoserineBy similarity
Modified residuei150 – 1501PhosphoserineBy similarity
Modified residuei152 – 1521PhosphoserineBy similarity
Modified residuei158 – 1581PhosphoserineBy similarity
Modified residuei284 – 2841N6-acetyllysineBy similarity
Modified residuei1723 – 17231Phosphoserine2 Publications
Modified residuei1794 – 17941PhosphoserineBy similarity
Modified residuei1808 – 18081PhosphoserineBy similarity
Modified residuei1973 – 19731PhosphoserineBy similarity
Modified residuei1975 – 19751PhosphoserineBy similarity
Modified residuei2027 – 20271PhosphoserineBy similarity
Modified residuei2029 – 20291PhosphoserineBy similarity
Modified residuei2031 – 20311PhosphoserineBy similarity
Modified residuei2073 – 20731N6-acetyllysine1 Publication
Modified residuei2181 – 21811PhosphothreonineBy similarity

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

MaxQBiQ9QX47.
PaxDbiQ9QX47.
PRIDEiQ9QX47.

PTM databases

PhosphoSiteiQ9QX47.

Expressioni

Tissue specificityi

Widely expressed. Highly expressed in brain, heart, spleen, liver, skeletal muscle, kidney and testis.1 Publication

Inductioni

By leptin. Highly expressed in hypothalamus following leptin injection.1 Publication

Gene expression databases

BgeeiQ9QX47.
CleanExiMM_SON.
ExpressionAtlasiQ9QX47. baseline and differential.
GenevestigatoriQ9QX47.

Interactioni

Subunit structurei

Interacts with SRSF2. Associates with the spliceosome (By similarity).By similarity

Protein-protein interaction databases

BioGridi203390. 1 interaction.
DIPiDIP-49510N.
IntActiQ9QX47. 6 interactions.
MINTiMINT-1713045.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati1001 – 100661-1
Repeati1009 – 101461-2
Repeati1016 – 102161-3
Repeati1025 – 103061-4
Repeati1033 – 103861-5
Repeati1041 – 104661-6
Repeati1050 – 105561-7
Repeati1058 – 106361-8
Repeati1066 – 107161-9
Repeati1075 – 108061-10
Repeati1084 – 108961-11
Repeati1095 – 110061-12
Repeati1106 – 111161-13
Repeati1115 – 112061-14
Repeati1950 – 195672-1
Repeati1959 – 1977193-1Add
BLAST
Repeati1978 – 198472-2
Repeati1985 – 199172-3
Repeati1992 – 199872-4
Repeati1999 – 200572-5
Repeati2006 – 201272-6
Repeati2013 – 201972-7; approximate
Repeati2020 – 2030113-2; approximateAdd
BLAST
Domaini2323 – 236947G-patchPROSITE-ProRule annotationAdd
BLAST
Domaini2389 – 244456DRBMPROSITE-ProRule annotationAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni721 – 85013013 X 10 AA tandem repeats of L-A-[ST]-[NSG]-[TS]-MDSQMAdd
BLAST
Regioni907 – 9837711 X 7 AA tandem repeats of [DR]-P-Y-R-[LI][AG][QHP]Add
BLAST
Regioni1001 – 112012014 X 6 AA repeats of [ED]-R-S-M-M-SAdd
BLAST
Regioni1141 – 1173333 X 11 AA tandem repats of P-P-L-P-P-E-E-P-P-[TME]-[MTG]Add
BLAST
Regioni1950 – 2019707 X 7 AA repeats of P-S-R-R-S-R-[TS]Add
BLAST
Regioni1959 – 2030722 X 19 AA repeats of P-S-R-R-R-R-S-R-S-V-V-R-R-R-S-F-S-I-SAdd
BLAST
Regioni2031 – 2057273 X tandem repeats of [ST]-P-[VLI]-R-[RL]-[RK]-[RF]-S-RAdd
BLAST

Domaini

Sequence similaritiesi

Contains 1 DRBM (double-stranded RNA-binding) domain.PROSITE-ProRule annotation
Contains 1 G-patch domain.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiNOG84537.
GeneTreeiENSGT00730000111141.
HOVERGENiHBG023160.
InParanoidiQ9QX47.
TreeFamiTF330344.

Family and domain databases

Gene3Di3.30.160.20. 1 hit.
InterProiIPR014720. dsRNA-bd_dom.
IPR000467. G_patch_dom.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF01585. G-patch. 1 hit.
[Graphical view]
SMARTiSM00443. G_patch. 1 hit.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiPS50137. DS_RBD. 1 hit.
PS50174. G_PATCH. 1 hit.
[Graphical view]

Sequences (4)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 4 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q9QX47-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAADIEQVFR SFVVSKFREI QQELSSGRSE GQLNGETNPP IEGNQAGDTA
60 70 80 90 100
ASARSLPNEE IVQKIEEVLS GVLDTELRYK PDLKEASRKS RCVSVQTDPT
110 120 130 140 150
DEVPTKKSKK HKKHKNKKKK KKKEKEKKYK RQPEESESKL KSHHDGNLES
160 170 180 190 200
DSFLKFDSEP SAAALEHPVR AFGLSEASET ALVLEPPVVS MEVQESHVLE
210 220 230 240 250
TLKPATKAAE LSVVSTSVIS EQSEQPMPGM LEPSMTKILD SFTAAPVPMS
260 270 280 290 300
TAALKSPEPV VTMSVEYQKS VLKSLETMPP ETSKTTLVEL PIAKVVEPSE
310 320 330 340 350
TLTIVSETPT EVHPEPSPST MDFPESSTTD VQRLPEQPVE APSEIADSSM
360 370 380 390 400
TRPQESLELP KTTAVELQES TVASALELPG PPATSILELQ GPPVTPVPEL
410 420 430 440 450
PGPSATPVPE LSGPLSTPVP ELPGPPATVV PELPGPSVTP VPQLSQELPG
460 470 480 490 500
PPAPSMGLEP PQEVPEPPVM AQELSGVPAV SAAIELTGQP AVTVAMELTE
510 520 530 540 550
QPVTTTEFEQ PVAMTTVEHP GHPEVTTATG LLGQPEAAMV LELPGQPVAT
560 570 580 590 600
TALELSGQPS VTGVPELSGL PSATRALELS GQSVATGALE LPGQLMATGA
610 620 630 640 650
LEFSGQSGAA GALELLGQPL ATGVLELPGQ PGAPELPGQP VATVALEISV
660 670 680 690 700
QSVVTTSELS TMTVSQSLEV PSTTALESYN TVAQELPTTL VGETSVTVGV
710 720 730 740 750
DPLMAQESHM LASNTMETHM LASNTMDSQM LASNTMDSQM LASNTMDSQM
760 770 780 790 800
LASSTMDSQM LASSTMDSQM LATSTMDSQM LATSSMDSQM LATSSMDSQM
810 820 830 840 850
LATSSMDSQM LATSSMDSQM LATSSMDSQM LATSSMDSQM LATSSMDSQM
860 870 880 890 900
LATSSMDSQM LASGAMDSQM LASGTMDAQM LASGTMDAQM LASSTQDSAM
910 920 930 940 950
MGSKSPDPYR LAQDPYRLAQ DPYRLGHDPY RLGHDAYRLG QDPYRLGHDP
960 970 980 990 1000
YRLTPDPYRV SPRPYRIAPR SYRIAPRPYR LAPRPLMLAS RRSMMMSYAA
1010 1020 1030 1040 1050
ERSMMSSYER SMMSYERSMM SPMAERSMMS AYERSMMSAY ERSMMSPMAE
1060 1070 1080 1090 1100
RSMMSAYERS MMSAYERSMM SPMADRSMMS MGADRSMMSS YSAADRSMMS
1110 1120 1130 1140 1150
SYSAADRSMM SSYTDRSMMS MAADSYTDSY TDSYTEAYMV PPLPPEEPPT
1160 1170 1180 1190 1200
MPPLPPEEPP MTPPLPPEEP PEGPALSTEQ SALTADNTWS TEVTLSTGES
1210 1220 1230 1240 1250
LSQPEPPVSQ SEISEPMAVP ANYSMSESET SMLASEAVMT VPEPAREPES
1260 1270 1280 1290 1300
SVTSAPVESA VVAEHEMVPE RPMTYMVSET TMSVEPAVLT SEASVISETS
1310 1320 1330 1340 1350
ETYDSMRPSG HAISEVTMSL LEPAVTISQP AENSLELPSM TVPAPSTMTT
1360 1370 1380 1390 1400
TESPVVAVTE IPPVAVPEPP IMAVPELPTM AVVKTPAVAV PEPLVAAPEP
1410 1420 1430 1440 1450
PTMATPELCS LSVSEPPVAV SELPALADPE HAITAVSGVS SLEPSVPILE
1460 1470 1480 1490 1500
PAVSVLQPVM IVSEPSVPVQ EPTVAVSEPA VIVSEHTQIT SPEMAVESSP
1510 1520 1530 1540 1550
VIVDSSVMSS QIMKGMNLLG GDENLGPEVG MQETLLHPGE EPRDGGHLKS
1560 1570 1580 1590 1600
DLYENEYDRN ADLTVNSHLI VKDAEHNTVC ATTVGPVGEA SEEKILPISE
1610 1620 1630 1640 1650
TKEITELATC AAVSEADIGR SLSSQLALEL DTVGTSKGFE FVTASALISE
1660 1670 1680 1690 1700
SKYDVEVSVT TQDTEHDMVI STSPSGGSEA DIEGPLPAKD IHLDLPSTNF
1710 1720 1730 1740 1750
VCKDVEDSLP IKESAQAVAV ALSPKESSED TEVPLPNKEI VPESGYSASI
1760 1770 1780 1790 1800
DEINEADLVR PLLPKDMERL TSLRAGIEGP LLASEVERDK SAASPVVISI
1810 1820 1830 1840 1850
PERASESSSE EKDDYEIFVK VKDTHEKSKK NKNRDKGEKE KKRDSSLRSR
1860 1870 1880 1890 1900
SKRSKSSEHK SRKRTSESRS RARKRSSKSK SHRSQTRSRS RSRRRRRSSR
1910 1920 1930 1940 1950
SRSKSRGRRS VSKEKRKRSP KHRSKSRERK RKRSSSRDNR KAARARSRTP
1960 1970 1980 1990 2000
SRRSRSHTPS RRRRSRSVGR RRSFSISPSR RSRTPSRRSR TPSRRSRTPS
2010 2020 2030 2040 2050
RRSRTPSRRS RTPSRRRRSR SAVRRRSFSI SPVRLRRSRT PLRRRFSRSP
2060 2070 2080 2090 2100
IRRKRSRSSE RGRSPKRLTD LDKAQLLEIA KANAAAMCAK AGVPLPPNLK
2110 2120 2130 2140 2150
PAPPPTIEEK VAKKSGGATI EELTEKCKQI AQSKEDDDVI VNKPHVSDEE
2160 2170 2180 2190 2200
EEEPPFYHHP FKLSEPKPIF FNLNIAAAKP TPPKSQVTLT KEFPVSSGSQ
2210 2220 2230 2240 2250
HRKKEADSVY GEWVPVEKNG EESKDDDNVF SSSLPSEPVD ISTAMSERAL
2260 2270 2280 2290 2300
AQKRLSENAF DLEAMSMLNR AQERIDAWAQ LNSIPGQFTG STGVQVLTQE
2310 2320 2330 2340 2350
QLANTGAQAW IKKDQFLRAA PVTGGMGAVL MRKMGWREGE GLGKNKEGNK
2360 2370 2380 2390 2400
EPILVDFKTD RKGLVAVGER AQKRSGNFSA AMKDLSGKHP VSALMEICNK
2410 2420 2430 2440
RRWQPPEFLL VHDSGPDHRK HFLFRVLRNG SPYQPNCMFF LNRY
Length:2,444
Mass (Da):265,651
Last modified:June 28, 2011 - v2
Checksum:iE873ADCB51B7123B
GO
Isoform 2 (identifier: Q9QX47-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     2126-2126: K → F
     2127-2444: Missing.

Show »
Length:2,126
Mass (Da):230,022
Checksum:iD977785966267327
GO
Isoform 3 (identifier: Q9QX47-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     776-815: Missing.

Show »
Length:2,404
Mass (Da):261,443
Checksum:i6163EBD3D5E8FB95
GO
Isoform 4 (identifier: Q9QX47-4) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     776-815: Missing.
     2238-2444: PVDISTAMSE...PNCMFFLNRY → GRVKRQGRVK...SRLYSSRFWW

Show »
Length:2,281
Mass (Da):247,971
Checksum:i10ABA0C4E10F6C03
GO

Sequence cautioni

The sequence AAH46419.1 differs from that shown. Reason: Contaminating sequence. Potential poly-A sequence.

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti857 – 8571D → E in AAF23120. (PubMed:10950926)Curated
Sequence conflicti857 – 8571D → E in AAF23121. (PubMed:10950926)Curated
Sequence conflicti857 – 8571D → E in BAJ40169. (PubMed:20876580)Curated
Sequence conflicti1333 – 13331N → D in AAF23120. (PubMed:10950926)Curated
Sequence conflicti1333 – 13331N → D in AAF23121. (PubMed:10950926)Curated
Sequence conflicti1734 – 17341P → L in AAF23120. (PubMed:10950926)Curated
Sequence conflicti1734 – 17341P → L in AAF23121. (PubMed:10950926)Curated
Sequence conflicti1966 – 19661R → I in AAF23120. (PubMed:10950926)Curated
Sequence conflicti1966 – 19661R → I in AAF23121. (PubMed:10950926)Curated

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei776 – 81540Missing in isoform 3 and isoform 4. 2 PublicationsVSP_041557Add
BLAST
Alternative sequencei2126 – 21261K → F in isoform 2. CuratedVSP_004416
Alternative sequencei2127 – 2444318Missing in isoform 2. CuratedVSP_004417Add
BLAST
Alternative sequencei2238 – 2444207PVDIS…FLNRY → GRVKRQGRVKRQMKQPAASH LTVTRCNSLCGTKPQSEKHR IAEKSVITSLPNIGPSMHLW EGSPRYNYLASRFASRLYSS RFWW in isoform 4. 1 PublicationVSP_041558Add
BLAST

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF193606
, AF193595, AF193596, AF193597, AF193598, AF193599, AF193600, AF193601, AF193602, AF193603, AF193604, AF193605 Genomic DNA. Translation: AAF23120.1.
AF193607 mRNA. Translation: AAF23121.1.
AB546195 mRNA. Translation: BAJ40169.1.
AC131691 Genomic DNA. No translation available.
BC046419 mRNA. Translation: AAH46419.1. Sequence problems.
AK019312 mRNA. Translation: BAB31659.1.
AK019081 mRNA. Translation: BAB31536.1.
AK008478 mRNA. Translation: BAB25691.1.
AK008256 mRNA. Translation: BAB25562.1.
CCDSiCCDS37399.1. [Q9QX47-1]
CCDS37400.1. [Q9QX47-2]
RefSeqiNP_849211.3. NM_178880.4. [Q9QX47-1]
UniGeneiMm.46401.
Mm.491378.

Genome annotation databases

EnsembliENSMUST00000114036; ENSMUSP00000109670; ENSMUSG00000022961. [Q9QX47-2]
ENSMUST00000114037; ENSMUSP00000109671; ENSMUSG00000022961. [Q9QX47-1]
GeneIDi20658.
KEGGimmu:20658.
UCSCiuc007zxy.1. mouse. [Q9QX47-2]
uc007zxz.1. mouse. [Q9QX47-1]
uc012aii.1. mouse. [Q9QX47-4]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF193606
, AF193595 , AF193596 , AF193597 , AF193598 , AF193599 , AF193600 , AF193601 , AF193602 , AF193603 , AF193604 , AF193605 Genomic DNA. Translation: AAF23120.1 .
AF193607 mRNA. Translation: AAF23121.1 .
AB546195 mRNA. Translation: BAJ40169.1 .
AC131691 Genomic DNA. No translation available.
BC046419 mRNA. Translation: AAH46419.1 . Sequence problems.
AK019312 mRNA. Translation: BAB31659.1 .
AK019081 mRNA. Translation: BAB31536.1 .
AK008478 mRNA. Translation: BAB25691.1 .
AK008256 mRNA. Translation: BAB25562.1 .
CCDSi CCDS37399.1. [Q9QX47-1 ]
CCDS37400.1. [Q9QX47-2 ]
RefSeqi NP_849211.3. NM_178880.4. [Q9QX47-1 ]
UniGenei Mm.46401.
Mm.491378.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 203390. 1 interaction.
DIPi DIP-49510N.
IntActi Q9QX47. 6 interactions.
MINTi MINT-1713045.

PTM databases

PhosphoSitei Q9QX47.

Proteomic databases

MaxQBi Q9QX47.
PaxDbi Q9QX47.
PRIDEi Q9QX47.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000114036 ; ENSMUSP00000109670 ; ENSMUSG00000022961 . [Q9QX47-2 ]
ENSMUST00000114037 ; ENSMUSP00000109671 ; ENSMUSG00000022961 . [Q9QX47-1 ]
GeneIDi 20658.
KEGGi mmu:20658.
UCSCi uc007zxy.1. mouse. [Q9QX47-2 ]
uc007zxz.1. mouse. [Q9QX47-1 ]
uc012aii.1. mouse. [Q9QX47-4 ]

Organism-specific databases

CTDi 6651.
MGIi MGI:98353. Son.

Phylogenomic databases

eggNOGi NOG84537.
GeneTreei ENSGT00730000111141.
HOVERGENi HBG023160.
InParanoidi Q9QX47.
TreeFami TF330344.

Miscellaneous databases

ChiTaRSi SON. mouse.
NextBioi 299093.
PROi Q9QX47.
SOURCEi Search...

Gene expression databases

Bgeei Q9QX47.
CleanExi MM_SON.
ExpressionAtlasi Q9QX47. baseline and differential.
Genevestigatori Q9QX47.

Family and domain databases

Gene3Di 3.30.160.20. 1 hit.
InterProi IPR014720. dsRNA-bd_dom.
IPR000467. G_patch_dom.
IPR017986. WD40_repeat_dom.
[Graphical view ]
Pfami PF01585. G-patch. 1 hit.
[Graphical view ]
SMARTi SM00443. G_patch. 1 hit.
[Graphical view ]
SUPFAMi SSF50978. SSF50978. 1 hit.
PROSITEi PS50137. DS_RBD. 1 hit.
PS50174. G_PATCH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Organization and conservation of the GART/SON/DONSON locus in mouse and human genomes."
    Wynn S.L., Fisher R.A., Pagel C., Price M., Liu Q.Y., Khan I.M., Zammit P., Dadrah K., Mazrani W., Kessling A., Lee J.S., Buluwela L.
    Genomics 68:57-62(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORMS 2 AND 3), NUCLEOTIDE SEQUENCE [MRNA] OF 1-2125 (ISOFORM 3), SUBCELLULAR LOCATION.
    Strain: 129/Sv.
  2. "Regulation of ghrelin signaling by a leptin-induced gene, negative regulatory element-binding protein, in the hypothalamic neurons."
    Komori T., Doi A., Furuta H., Wakao H., Nakao N., Nakazato M., Nanjo K., Senba E., Morikawa Y.
    J. Biol. Chem. 285:37884-37894(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 4), FUNCTION, TISSUE SPECIFICITY, INDUCTION.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-1827 (ISOFORM 1).
    Strain: FVB/N.
    Tissue: Kidney.
  5. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-116.
    Strain: C57BL/6J.
    Tissue: Hippocampus, Small intestine and Tongue.
  6. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1723, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Liver.
  7. "The phagosomal proteome in interferon-gamma-activated macrophages."
    Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.
    Immunity 30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1723, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  8. "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
    Park J., Chen Y., Tishkoff D.X., Peng C., Tan M., Dai L., Xie Z., Zhang Y., Zwaans B.M., Skinner M.E., Lombard D.B., Zhao Y.
    Mol. Cell 50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-2073, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Embryonic fibroblast.

Entry informationi

Entry nameiSON_MOUSE
AccessioniPrimary (citable) accession number: Q9QX47
Secondary accession number(s): E3WC91
, E9PXW2, E9Q3H8, E9Q3I0, E9Q6M4, E9Q7G2, E9QAR8, E9QMT0, Q811G3, Q9CQ12, Q9CQK6, Q9QXP5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 23, 2002
Last sequence update: June 28, 2011
Last modified: October 29, 2014
This is version 119 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3