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Q9QX38

- Q9QX38_RAT

UniProt

Q9QX38 - Q9QX38_RAT

Protein
Submitted name:

Neuropilin

Gene

Nrp1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 90 (01 Oct 2014)
      Sequence version 1 (01 May 2000)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi194 – 1941CalciumUniRule annotation
    Metal bindingi208 – 2081CalciumUniRule annotation
    Metal bindingi249 – 2491CalciumUniRule annotation

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. semaphorin receptor activity Source: InterPro
    3. vascular endothelial growth factor-activated receptor activity Source: InterPro

    GO - Biological processi

    1. angiogenesis Source: InterPro
    2. axon guidance Source: InterPro
    3. cell adhesion Source: InterPro
    4. endothelial cell chemotaxis Source: InterPro
    5. organ morphogenesis Source: InterPro
    6. vascular endothelial growth factor receptor signaling pathway Source: InterPro

    Keywords - Ligandi

    CalciumUniRule annotation, Metal-bindingUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    NeuropilinImported
    Gene namesi
    Name:Nrp1Imported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

    Organism-specific databases

    RGDi621588. Nrp1.

    Subcellular locationi

    GO - Cellular componenti

    1. membrane Source: InterPro

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Disulfide bondi26 ↔ 53UniRule annotation
    Disulfide bondi26 ↔ 53 By similarity
    Disulfide bondi81 ↔ 103UniRule annotation
    Disulfide bondi81 ↔ 103 By similarity
    Disulfide bondi146 ↔ 172UniRule annotation
    Disulfide bondi146 ↔ 172 By similarity
    Disulfide bondi205 ↔ 227UniRule annotation
    Disulfide bondi205 ↔ 227 By similarity

    Keywords - PTMi

    Disulfide bondUniRule annotation

    Proteomic databases

    PRIDEiQ9QX38.

    Expressioni

    Gene expression databases

    GenevestigatoriQ9QX38.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9QX38.
    SMRiQ9QX38. Positions 144-585.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 2 F5/8 type C domains.UniRule annotation

    Phylogenomic databases

    HOVERGENiHBG000502.
    InParanoidiQ9QX38.

    Family and domain databases

    Gene3Di2.60.120.260. 2 hits.
    2.60.120.290. 2 hits.
    InterProiIPR000421. Coagulation_fac_5/8-C_type_dom.
    IPR008985. ConA-like_lec_gl_sf.
    IPR000859. CUB_dom.
    IPR008979. Galactose-bd-like.
    IPR000998. MAM_dom.
    IPR014648. Neuropilin.
    IPR022579. Neuropilin1_C.
    IPR027146. NRP1.
    [Graphical view]
    PANTHERiPTHR10127:SF616. PTHR10127:SF616. 1 hit.
    PfamiPF00431. CUB. 2 hits.
    PF11980. DUF3481. 1 hit.
    PF00754. F5_F8_type_C. 2 hits.
    PF00629. MAM. 1 hit.
    [Graphical view]
    PIRSFiPIRSF036960. Neuropilin. 1 hit.
    PRINTSiPR00020. MAMDOMAIN.
    SMARTiSM00042. CUB. 2 hits.
    SM00231. FA58C. 2 hits.
    SM00137. MAM. 1 hit.
    [Graphical view]
    SUPFAMiSSF49785. SSF49785. 2 hits.
    SSF49854. SSF49854. 2 hits.
    SSF49899. SSF49899. 1 hit.
    PROSITEiPS01180. CUB. 2 hits.
    PS01285. FA58C_1. 2 hits.
    PS01286. FA58C_2. 2 hits.
    PS50022. FA58C_3. 2 hits.
    PS00740. MAM_1. 1 hit.
    PS50060. MAM_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9QX38-1 [UniParc]FASTAAdd to Basket

    « Hide

    MERGLPLLCA TLALALALGA FRSDKCGGTI KIENPGYLTS PGYPHSYHPS    50
    EKCEWLIQAP EPYQRIMINF NPHFDLEDRD CKYDYVEVID GENEGGRLWG 100
    KFCGKIAPSP VVSSGPFLFI KFVSDYETHG AGFSIRYEIF KRGPECSQNY 150
    TAPTGVIKSP GFPEKYPNSL ECTYIIFAPK MSEIILEFES FDLEQDSNPP 200
    GGMFCRYDRL EIWDGFPEVG PHIGRYCGQK TPGRIRSSSG ILSMVFYTDS 250
    AIAKEGFSAN YSVLQSSISE DFKCMEALGM ESGEIHSDQI TASSQYGTNW 300
    SVERSRLNYP ENGWTPGEDS YREWIQVDLG LLRFVTAVGT QGAISKETKK 350
    KYYVKTYRVD ISSNGEDWIT LKEGNKAIIF QGNTNPTDVV FGVFPKPLIT 400
    RFVRIKPASW ETGISMRFEV YGCKITDYPC SGMLGMVSGL ISDSQITASN 450
    QGDRNWMPEN IRLVTSRTGW ALPPSPHPYI NEWLQVDLGD EKIVRGVIIQ 500
    GGKHRENKVF MRKFKIAYSN NGSDWKMIMD DSKRKAKSFE GNNNYDTPEL 550
    RAFTPLSTRF IRIYPERATH SGLGLRMELL GCEVEVPTAG PTTPNGNPVD 600
    ECDDDQANCH SGTGDDFQLT GGTTVLATEK PTIIDSTIQS EFPTYGFNCE 650
    FGWGSHKTFC HWEHDSHAQL RWRVLTSKTG PIQDHTGDGN FIYSQADENQ 700
    KGKVARLVSP VVYSQSSAHC MTFWYHMSGS HVGTLRVKLH YQKPEEYDQL 750
    VWMVVGHQGD HWKEGRVLLH KSLKLYQVIF EGEIGKGNLG GIAVDDISIN 800
    NHIPQEDCAK PTDLDKKNTE IKIDETGSTP GYEEGKGDKN ISRKPGNVLK 850
    TLDPILITII AMSALGVLLG AVCGVVLYCA CWHNGMSERN LSALENYNFE 900
    LVDGVKLKKD KLNPHSNYSE A 921
    Length:921
    Mass (Da):103,052
    Last modified:May 1, 2000 - v1
    Checksum:i58B29A9AA4978971
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF018957 mRNA. Translation: AAC53345.1.
    UniGeneiRn.10815.
    Rn.165344.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF018957 mRNA. Translation: AAC53345.1 .
    UniGenei Rn.10815.
    Rn.165344.

    3D structure databases

    ProteinModelPortali Q9QX38.
    SMRi Q9QX38. Positions 144-585.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q9QX38.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    RGDi 621588. Nrp1.

    Phylogenomic databases

    HOVERGENi HBG000502.
    InParanoidi Q9QX38.

    Gene expression databases

    Genevestigatori Q9QX38.

    Family and domain databases

    Gene3Di 2.60.120.260. 2 hits.
    2.60.120.290. 2 hits.
    InterProi IPR000421. Coagulation_fac_5/8-C_type_dom.
    IPR008985. ConA-like_lec_gl_sf.
    IPR000859. CUB_dom.
    IPR008979. Galactose-bd-like.
    IPR000998. MAM_dom.
    IPR014648. Neuropilin.
    IPR022579. Neuropilin1_C.
    IPR027146. NRP1.
    [Graphical view ]
    PANTHERi PTHR10127:SF616. PTHR10127:SF616. 1 hit.
    Pfami PF00431. CUB. 2 hits.
    PF11980. DUF3481. 1 hit.
    PF00754. F5_F8_type_C. 2 hits.
    PF00629. MAM. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF036960. Neuropilin. 1 hit.
    PRINTSi PR00020. MAMDOMAIN.
    SMARTi SM00042. CUB. 2 hits.
    SM00231. FA58C. 2 hits.
    SM00137. MAM. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49785. SSF49785. 2 hits.
    SSF49854. SSF49854. 2 hits.
    SSF49899. SSF49899. 1 hit.
    PROSITEi PS01180. CUB. 2 hits.
    PS01285. FA58C_1. 2 hits.
    PS01286. FA58C_2. 2 hits.
    PS50022. FA58C_3. 2 hits.
    PS00740. MAM_1. 1 hit.
    PS50060. MAM_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Neuropilin is a receptor for the axonal chemorepellent semaphorin III."
      He Z., Tessier-Lavigne M.
      Cell 90:739-751(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ9QX38_RAT
    AccessioniPrimary (citable) accession number: Q9QX38
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 1, 2000
    Last sequence update: May 1, 2000
    Last modified: October 1, 2014
    This is version 90 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)