SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9QWY8

- ASAP1_MOUSE

UniProt

Q9QWY8 - ASAP1_MOUSE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
Gene
Asap1, Ddef1, Kiaa1249, Shag1
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

May function as a signal transduction protein involved in the differentiation of fibroblasts into adipocytes and possibly other cell types. Plays a role in ciliogenesis By similarity. Posseses phosphatidylinositol 4,5-bisphosphate-dependent GTPase-activating protein activity for ARF1 (ADP ribosylation factor 1) and ARF5 and a lesser activity towards ARF6. May coordinate membrane trafficking with cell growth or actin cytoskeleton remodeling by binding to both SRC and PIP2.

Enzyme regulationi

Activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2).

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri469 – 49224C4-type
Add
BLAST

GO - Molecular functioni

  1. ARF GTPase activator activity Source: FlyBase
  2. phosphatidylinositol-3,4,5-trisphosphate binding Source: FlyBase
  3. phosphatidylinositol-4,5-bisphosphate binding Source: FlyBase
  4. protein binding Source: IntAct
  5. zinc ion binding Source: InterPro

GO - Biological processi

  1. cilium morphogenesis Source: UniProtKB
  2. positive regulation of GTPase activity Source: GOC
  3. regulation of ARF GTPase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

GTPase activation

Keywords - Biological processi

Cilium biogenesis/degradation

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
Alternative name(s):
130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein
ADP-ribosylation factor-directed GTPase-activating protein 1
Short name:
ARF GTPase-activating protein 1
Development and differentiation-enhancing factor 1
Short name:
DEF-1
Short name:
Differentiation-enhancing factor 1
PIP2-dependent ARF1 GAP
Gene namesi
Name:Asap1
Synonyms:Ddef1, Kiaa1249, Shag1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 15

Organism-specific databases

MGIiMGI:1342335. Asap1.

Subcellular locationi

Cytoplasm. Membrane
Note: Predominantly cytoplasmic. Partially membrane-associated.

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
  2. membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Membrane

Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Mutagenesisi811 – 8111R → A: Significant reduction in binding to SRC and CRK and loss of phosphorylation. Loss of binding and phosphorylation; when associated with A-910 and A-913. 1 Publication
Mutagenesisi910 – 9101P → A: Significant reduction in binding to SRC and CRK and decrease in phosphorylation; when associated with A-913. Loss of binding and phosphorylation; when associated with A-811 and A-913. 1 Publication
Mutagenesisi913 – 9131P → A: Significant reduction in binding to SRC and CRK and decrease in phosphorylation; when associated with A-910. Loss of binding and phosphorylation; when associated with A-811 and A-910. 1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 11471147Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
PRO_0000074197Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei308 – 3081Phosphotyrosine; by FAK21 Publication
Modified residuei732 – 7321Phosphoserine1 Publication
Modified residuei858 – 8581Phosphoserine1 Publication
Modified residuei1026 – 10261Phosphoserine By similarity
Modified residuei1045 – 10451Phosphoserine By similarity

Post-translational modificationi

Phosphorylated on tyrosine residues by SRC.1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ9QWY8.
PaxDbiQ9QWY8.
PRIDEiQ9QWY8.

PTM databases

PhosphoSiteiQ9QWY8.

Miscellaneous databases

PMAP-CutDBQ9QWY8.

Expressioni

Tissue specificityi

Expressed in all tissues examined but a most abundant expression was found in the testis, brain, lung and spleen. A heightened expression was seen in the adipose tissue from obese (ob) and diabetic (db) animals.1 Publication

Gene expression databases

ArrayExpressiQ9QWY8.
GenevestigatoriQ9QWY8.

Interactioni

Subunit structurei

Homodimer. Interacts with SRC and CRK. Interacts with RAB11FIP3. Interacts with PTK2B/PYK2.2 Publications

Binary interactionsi

WithEntry#Exp.IntActNotes
SRCP005233EBI-698524,EBI-848039From a different organism.

Protein-protein interaction databases

IntActiQ9QWY8. 8 interactions.
MINTiMINT-266354.

Structurei

3D structure databases

ProteinModelPortaliQ9QWY8.
SMRiQ9QWY8. Positions 341-443, 452-724, 1087-1147.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini339 – 43193PH
Add
BLAST
Domaini454 – 577124Arf-GAP
Add
BLAST
Repeati615 – 64733ANK 1
Add
BLAST
Repeati651 – 68030ANK 2
Add
BLAST
Domaini1085 – 114763SH3
Add
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi798 – 1011214Pro-rich
Add
BLAST

Domaini

The PH domain most probably contributes to the phosphoinositide-dependent regulation of ADP ribosylation factors.

Sequence similaritiesi

Contains 2 ANK repeats.
Contains 1 Arf-GAP domain.
Contains 1 PH domain.
Contains 1 SH3 domain.

Keywords - Domaini

ANK repeat, Repeat, SH3 domain, Zinc-finger

Phylogenomic databases

eggNOGiCOG5347.
GeneTreeiENSGT00740000115306.
HOGENOMiHOG000230570.
HOVERGENiHBG051327.
InParanoidiQ9QWY8.
KOiK12488.
OMAiDFLVQNC.
TreeFamiTF325156.

Family and domain databases

Gene3Di1.20.1270.60. 1 hit.
1.25.40.20. 1 hit.
2.30.29.30. 1 hit.
InterProiIPR027267. AH/BAR-dom.
IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR001164. ArfGAP.
IPR001849. PH_domain.
IPR011993. PH_like_dom.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF12796. Ank_2. 1 hit.
PF01412. ArfGap. 1 hit.
PF00169. PH. 1 hit.
PF00018. SH3_1. 1 hit.
[Graphical view]
PRINTSiPR00405. REVINTRACTNG.
SMARTiSM00248. ANK. 2 hits.
SM00105. ArfGap. 1 hit.
SM00233. PH. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
SSF50044. SSF50044. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 2 hits.
PS50115. ARFGAP. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
PS50002. SH3. 1 hit.
[Graphical view]

Sequences (4)i

Sequence statusi: Complete.

This entry describes 4 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q9QWY8-1) [UniParc]FASTAAdd to Basket

Also known as: SHAG1a, ASAP1a

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MRSSASRLSS FSSRDSLWNR MPDQISVSEF IAETTEDYNS PTTSSFTTRL     50
HNCRNTVTLL EEALDQDRTA LQKVKKSVKA IYNSGQDHVQ NEENYAQVLD 100
KFGSNFLSRD NPDLGTAFVK FSTLTKELST LLKNLLQGLS HNVIFTLDSL 150
LKGDLKGVKG DLKKPFDKAW KDYETKFTKI EKEKREHAKQ HGMIRTEITG 200
AEIAEEMEKE RRLFQLQMCE YLIKVNEIKT KKGVDLLQNL IKYYHAQCNF 250
FQDGLKTADK LKQYIEKLAA DLYNIKQTQD EEKKQLTALR DLIKSSLQLD 300
PKEVGGLYVA SRANSSRRDS QSRQGGYSMH QLQGNKEYGS EKKGFLLKKS 350
DGIRKVWQRR KCAVKNGILT ISHATSNRQP AKLNLLTCQV KPNAEDKKSF 400
DLISHNRTYH FQAEDEQDYI AWISVLTNSK EEALTMAFRG EQSTGENSLE 450
DLTKAIIEDV QRLPGNDICC DCGSSEPTWL STNLGILTCI ECSGIHREMG 500
VHISRIQSLE LDKLGTSELL LAKNVGNNSF NDIMEANLPS PSPKPTPSSD 550
MTVRKEYITA KYVDHRFSRK TCASSSAKLN ELLEAIKSRD LLALIQVYAE 600
GVELMEPLLE PGQELGETAL HLAVRTADQT SLHLVDFLVQ NCGNLDKQTS 650
VGNTVLHYCS MYGKPECLKL LLRSKPTVDI VNQNGETALD IAKRLKATQC 700
EDLLSQAKSG KFNPHVHVEY EWNLRQDEMD ESDDDLDDKP SPIKKERSPR 750
PQSFCHSSSI SPQDKLALPG FSTPRDKQRL SYGAFTNQIF ASTSTDLPTS 800
PTSEAPPLPP RNAGKGPTGP PSTLPLGTQT SSGSSTLSKK RPPPPPPGHK 850
RTLSDPPSPL PHGPPNKGAI PWGNDVGPLS SSKTANKFEG LSQQASTSSA 900
KTALGPRVLP KLPQKVALRK TETSHHLSLD RTNIPPETFQ KSSQLTELPQ 950
KPPLGELPPK PVELAPKPQV GELPPKPGEL PPKPQLGDLP PKPQLSDLPP 1000
KPQMKDLPPK PQLGDLLAKS QAGDVSAKVQ PPSEVTQRSH TGDLSPNVQS 1050
RDAIQKQASE DSNDLTPTLP ETPVPLPRKI NTGKNKVRRV KTIYDCQADN 1100
DDELTFIEGE VIIVTGEEDQ EWWIGHIEGQ PERKGVFPVS FVHILSD 1147
Length:1,147
Mass (Da):127,421
Last modified:October 3, 2012 - v2
Checksum:i12950D1C4F49A909
GO
Isoform 2 (identifier: Q9QWY8-2) [UniParc]FASTAAdd to Basket

Also known as: SHAG1b, ASAP1b

The sequence of this isoform differs from the canonical sequence as follows:
     816-872: Missing.

Show »
Length:1,090
Mass (Da):121,675
Checksum:i5C1F1D950B7B252A
GO
Isoform 3 (identifier: Q9QWY8-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     304-315: Missing.

Show »
Length:1,135
Mass (Da):126,246
Checksum:i636A1D0E72FB8893
GO
Isoform 4 (identifier: Q9QWY8-4) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     304-318: Missing.

Show »
Length:1,132
Mass (Da):125,846
Checksum:i32751FB034E7CD51
GO

Sequence cautioni

The sequence AAH02201.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
The sequence AAH48818.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei304 – 31815Missing in isoform 4.
VSP_008367Add
BLAST
Alternative sequencei304 – 31512Missing in isoform 3.
VSP_008366Add
BLAST
Alternative sequencei816 – 87257Missing in isoform 2.
VSP_008368Add
BLAST

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti654 – 6541T → S in AAB82338. 1 Publication
Sequence conflicti879 – 8791L → S in AAC98349. 1 Publication
Sequence conflicti879 – 8791L → S in AAC98350. 1 Publication
Sequence conflicti1051 – 10511R → I in AAB82338. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF075461 mRNA. Translation: AAC98349.1.
AF075462 mRNA. Translation: AAC98350.1.
AC098728 Genomic DNA. No translation available.
AC131710 Genomic DNA. No translation available.
AC156573 Genomic DNA. No translation available.
BC002201 mRNA. Translation: AAH02201.1. Different initiation.
BC048818 mRNA. Translation: AAH48818.1. Different initiation.
BC094581 mRNA. Translation: AAH94581.1.
AK122477 mRNA. Translation: BAC65759.1.
U92478 mRNA. Translation: AAB82338.1.
CCDSiCCDS56986.1. [Q9QWY8-1]
CCDS70634.1. [Q9QWY8-2]
PIRiT42627.
RefSeqiNP_001263390.1. NM_001276461.1.
NP_001263391.1. NM_001276462.1.
NP_001263396.1. NM_001276467.1. [Q9QWY8-2]
NP_034156.2. NM_010026.3. [Q9QWY8-1]
UniGeneiMm.277236.
Mm.491089.

Genome annotation databases

EnsembliENSMUST00000110115; ENSMUSP00000105742; ENSMUSG00000022377. [Q9QWY8-4]
ENSMUST00000175793; ENSMUSP00000135718; ENSMUSG00000022377. [Q9QWY8-3]
ENSMUST00000176384; ENSMUSP00000135190; ENSMUSG00000022377. [Q9QWY8-2]
ENSMUST00000177374; ENSMUSP00000134825; ENSMUSG00000022377. [Q9QWY8-1]
GeneIDi13196.
KEGGimmu:13196.
UCSCiuc007vzh.1. mouse. [Q9QWY8-3]
uc007vzk.1. mouse.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF075461 mRNA. Translation: AAC98349.1 .
AF075462 mRNA. Translation: AAC98350.1 .
AC098728 Genomic DNA. No translation available.
AC131710 Genomic DNA. No translation available.
AC156573 Genomic DNA. No translation available.
BC002201 mRNA. Translation: AAH02201.1 . Different initiation.
BC048818 mRNA. Translation: AAH48818.1 . Different initiation.
BC094581 mRNA. Translation: AAH94581.1 .
AK122477 mRNA. Translation: BAC65759.1 .
U92478 mRNA. Translation: AAB82338.1 .
CCDSi CCDS56986.1. [Q9QWY8-1 ]
CCDS70634.1. [Q9QWY8-2 ]
PIRi T42627.
RefSeqi NP_001263390.1. NM_001276461.1.
NP_001263391.1. NM_001276462.1.
NP_001263396.1. NM_001276467.1. [Q9QWY8-2 ]
NP_034156.2. NM_010026.3. [Q9QWY8-1 ]
UniGenei Mm.277236.
Mm.491089.

3D structure databases

ProteinModelPortali Q9QWY8.
SMRi Q9QWY8. Positions 341-443, 452-724, 1087-1147.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi Q9QWY8. 8 interactions.
MINTi MINT-266354.

PTM databases

PhosphoSitei Q9QWY8.

Proteomic databases

MaxQBi Q9QWY8.
PaxDbi Q9QWY8.
PRIDEi Q9QWY8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000110115 ; ENSMUSP00000105742 ; ENSMUSG00000022377 . [Q9QWY8-4 ]
ENSMUST00000175793 ; ENSMUSP00000135718 ; ENSMUSG00000022377 . [Q9QWY8-3 ]
ENSMUST00000176384 ; ENSMUSP00000135190 ; ENSMUSG00000022377 . [Q9QWY8-2 ]
ENSMUST00000177374 ; ENSMUSP00000134825 ; ENSMUSG00000022377 . [Q9QWY8-1 ]
GeneIDi 13196.
KEGGi mmu:13196.
UCSCi uc007vzh.1. mouse. [Q9QWY8-3 ]
uc007vzk.1. mouse.

Organism-specific databases

CTDi 50807.
MGIi MGI:1342335. Asap1.
Rougei Search...

Phylogenomic databases

eggNOGi COG5347.
GeneTreei ENSGT00740000115306.
HOGENOMi HOG000230570.
HOVERGENi HBG051327.
InParanoidi Q9QWY8.
KOi K12488.
OMAi DFLVQNC.
TreeFami TF325156.

Miscellaneous databases

NextBioi 283328.
PMAP-CutDB Q9QWY8.
PROi Q9QWY8.
SOURCEi Search...

Gene expression databases

ArrayExpressi Q9QWY8.
Genevestigatori Q9QWY8.

Family and domain databases

Gene3Di 1.20.1270.60. 1 hit.
1.25.40.20. 1 hit.
2.30.29.30. 1 hit.
InterProi IPR027267. AH/BAR-dom.
IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR001164. ArfGAP.
IPR001849. PH_domain.
IPR011993. PH_like_dom.
IPR001452. SH3_domain.
[Graphical view ]
Pfami PF12796. Ank_2. 1 hit.
PF01412. ArfGap. 1 hit.
PF00169. PH. 1 hit.
PF00018. SH3_1. 1 hit.
[Graphical view ]
PRINTSi PR00405. REVINTRACTNG.
SMARTi SM00248. ANK. 2 hits.
SM00105. ArfGap. 1 hit.
SM00233. PH. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view ]
SUPFAMi SSF48403. SSF48403. 1 hit.
SSF50044. SSF50044. 1 hit.
PROSITEi PS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 2 hits.
PS50115. ARFGAP. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
PS50002. SH3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "ASAP1, a phospholipid-dependent arf GTPase-activating protein that associates with and is phosphorylated by Src."
    Brown M.T., Andrade J., Radhakrishna H., Donaldson J.G., Cooper J.A., Randazzo P.A.
    Mol. Cell. Biol. 18:7038-7051(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2), CHARACTERIZATION, MUTAGENESIS OF ARG-811; PRO-910 AND PRO-913.
    Tissue: Brain and Embryo.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 20-1147 (ISOFORM 4).
    Strain: C57BL/6.
    Tissue: Eye and Mammary tumor.
  4. "Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
    Okazaki N., Kikuno R., Ohara R., Inamoto S., Aizawa H., Yuasa S., Nakajima D., Nagase T., Ohara O., Koga H.
    DNA Res. 10:35-48(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 57-1147 (ISOFORM 3).
    Tissue: Brain.
  5. "Examining the specificity of Src homology 3 domain -- ligand interactions with alkaline phosphatase fusion proteins."
    Yamabhai M., Kay B.K.
    Anal. Biochem. 247:143-151(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 654-1147 (ISOFORM 1).
  6. "DEF-1, a novel src SH3 binding protein that promotes adipogenesis in fibroblastic cell lines."
    King F.J., Hu E., Harris D.F., Sarraf P., Spiegelman B.M., Roberts T.M.
    Mol. Cell. Biol. 19:2330-2337(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: TISSUE SPECIFICITY.
  7. "The tyrosine kinase Pyk2 regulates Arf1 activity by phosphorylation and inhibition of the Arf-GTPase-activating protein ASAP1."
    Kruljac-Letunic A., Moelleken J., Kallin A., Wieland F., Blaukat A.
    J. Biol. Chem. 278:29560-29570(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION AT TYR-308, INTERACTION WITH PTK2B/PYK2.
  8. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-732 AND SER-858, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Liver.
  9. "Arf GTPase-activating protein ASAP1 interacts with Rab11 effector FIP3 and regulates pericentrosomal localization of transferrin receptor-positive recycling endosome."
    Inoue H., Ha V.L., Prekeris R., Randazzo P.A.
    Mol. Biol. Cell 19:4224-4237(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH RAB11FIP3.

Entry informationi

Entry nameiASAP1_MOUSE
AccessioniPrimary (citable) accession number: Q9QWY8
Secondary accession number(s): O08612
, Q505F0, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 26, 2003
Last sequence update: October 3, 2012
Last modified: September 3, 2014
This is version 130 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi