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Unreviewed, UniProtKB/TrEMBL Q9QWR5 (Q9QWR5_MOUSE)

Last modified January 19, 2010. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information

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Names and origin

Protein namesSubmitted name:
    p21 protein EMBL BAA28218.1
Gene names
Name: Kras MGI 96680
Synonyms: Nras MGI 97376, ras EMBL BAA28218.1
OrganismMus musculus (Mouse) EMBL BAA28218.1
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

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Protein attributes

Sequence length36 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level.

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Ontologies

Keywords
   LigandGTP-binding RuleBase RU003312V0
Nucleotide-binding
Gene Ontology (GO)
   Biological processRas protein signal transduction

Inferred from genetic interaction. Source: MGI

actin cytoskeleton organization

Inferred from genetic interaction. Source: MGI

apoptosis

Inferred from electronic annotation. Source: Compara

cytokine-mediated signaling pathway

Inferred from electronic annotation. Source: Compara

negative regulation of neuron apoptosis

Inferred from genetic interaction. Source: MGI

positive regulation of DNA replication

Inferred from electronic annotation. Source: Compara

positive regulation of MAP kinase activity

Inferred from electronic annotation. Source: Compara

positive regulation of NF-kappaB transcription factor activity

Inferred from electronic annotation. Source: Compara

positive regulation of Rac protein signal transduction

Inferred from genetic interaction. Source: MGI

positive regulation of cell proliferation

Inferred from genetic interaction. Source: MGI

positive regulation of nitric-oxide synthase activity

Inferred from electronic annotation. Source: Compara

protein heterooligomerization

Inferred from electronic annotation. Source: Compara

regulation of cell cycle

Traceable author statement. Source: MGI

regulation of long-term neuronal synaptic plasticity

Inferred from genetic interaction. Source: MGI

regulation of synaptic transmission, GABAergic

Inferred from genetic interaction. Source: MGI

response to glucocorticoid stimulus

Inferred from electronic annotation. Source: Compara

response to mineralocorticoid stimulus

Inferred from electronic annotation. Source: Compara

striated muscle cell differentiation

Inferred from genetic interaction. Source: MGI

visual learning

Inferred from genetic interaction. Source: MGI

   Cellular componentmembrane fraction

Inferred from direct assay. Source: MGI

membrane raft

Inferred from electronic annotation. Source: Compara

plasma membrane

Inferred from electronic annotation. Source: Compara

   Molecular functionGDP binding

Inferred from electronic annotation. Source: Compara

GMP binding

Inferred from electronic annotation. Source: Compara

GTP binding

Inferred from electronic annotation. Source: UniProtKB-KW

GTPase activity

Inferred from genetic interaction. Source: MGI

LRR domain binding

Inferred from electronic annotation. Source: Compara

protein C-terminus binding

Inferred from electronic annotation. Source: Compara

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL BAA28218.1
Non-terminal residue361 EMBL BAA28218.1

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Sequences

Sequence LengthMass (Da)Tools
Q9QWR5-1 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: C73AC89DFE3A2A51

FASTA364,055
        10         20         30 
QVVIDGETCL LDILDTAGQE EYSAMRDQYM RTGEGF

« Hide

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References

[1]"Loss of the normal N-ras allele in a mouse thymic lymphoma induced by a chemical carcinogen."
Guerrero I., Villasante A., Corces V., Pellicer A.
Proc. Natl. Acad. Sci. U.S.A. 82:7810-7814(1985) [PubMed: 3865197] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: BALB/c nu/nu EMBL BAA28218.1.
[2]"Alterations of mouse proto-oncogenes in sarcomas induced after transplantation of human tumors in athymic nude mice."
Yuasa Y., Yamazaki H., Maruo K., Ueyama Y., Shibuya M., Tamaoki N.
Jpn. J. Cancer Res. 81:333-339(1990) [PubMed: 2114387] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: BALB/c nu/nu EMBL BAA28218.1.
+Additional computationally mapped references.

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		D00836 Genomic DNA. Translation: BAA28218.1.
IPIIPI00134941.
UniGeneMm.400954

3D structure databases

HSSPHSSP built from PDB template 1HE8 based on UniProtKB P01112.
SMRQ9QWR5. Positions 1-36.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ9QWR5.

Genome annotation databases

EnsemblENSMUST00000026572; ENSMUSP00000026572; ENSMUSG00000025499; Mus musculus. [Genome view]
ENSMUST00000029445; ENSMUSP00000029445; ENSMUSG00000027852; Mus musculus. [Genome view]
ENSMUST00000032397; ENSMUSP00000032397; ENSMUSG00000030265; Mus musculus. [Genome view]
ENSMUST00000032399; ENSMUSP00000032399; ENSMUSG00000030265; Mus musculus. [Genome view]
ENSMUST00000093979; ENSMUSP00000091515; ENSMUSG00000025499; Mus musculus. [Genome view]
ENSMUST00000097957; ENSMUSP00000095570; ENSMUSG00000025499; Mus musculus. [Genome view]
ENSMUST00000111710; ENSMUSP00000107339; ENSMUSG00000030265; Mus musculus. [Genome view]

Organism-specific databases

MGIMGI:96680. Kras.
MGI:97376. Nras.

Phylogenomic databases

HOVERGENQ9QWR5.
InParanoidQ9QWR5.

Gene expression databases

ArrayExpressQ9QWR5.
BgeeQ9QWR5.
GenevestigatorQ9QWR5.

Family and domain databases

InterProIPR013753. Ras.
IPR020849. Ras_small_GTPase.
[Graphical view]
PfamPF00071. Ras. 1 hit.
[Graphical view]
PROSITEPS51421. RAS. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

SOURCESearch...

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Entry information

Entry nameQ9QWR5_MOUSE
AccessionPrimary (citable) accession number: Q9QWR5
Entry history
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: January 19, 2010
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
Names and origin · Protein attributes · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information