Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Cyclic nucleotide-gated channel

Gene

Cnga3

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • cGMP binding Source: RGD
  • intracellular cGMP activated cation channel activity Source: RGD
  • protein C-terminus binding Source: RGD
  • signal transducer activity Source: RGD

GO - Biological processi

  • ion transmembrane transport Source: RGD
  • response to cAMP Source: RGD
  • response to corticosteroid Source: RGD
  • response to magnesium ion Source: RGD
Complete GO annotation...

Keywords - Biological processi

Ion transportSAAS annotation, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Cyclic nucleotide-gated channelImported
Gene namesi
Name:Cnga3Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi70948. Cnga3.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei227 – 245HelicalSequence analysisAdd BLAST19
Transmembranei299 – 321HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

  • cytoplasm Source: RGD
  • dendrite Source: RGD
  • intracellular cyclic nucleotide activated cation channel complex Source: RGD
  • neuronal cell body Source: RGD
  • perikaryon Source: RGD
  • photoreceptor outer segment membrane Source: RGD
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ9QWN7.

Expressioni

Gene expression databases

GenevisibleiQ9QWN7. RN.

Interactioni

GO - Molecular functioni

  • protein C-terminus binding Source: RGD

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000056459.

Structurei

3D structure databases

ProteinModelPortaliQ9QWN7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini403 – 517Cyclic nucleotide-bindingInterPro annotationAdd BLAST115

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG0500. Eukaryota.
ENOG410YWWI. LUCA.
HOVERGENiHBG000281.
KOiK04950.

Family and domain databases

Gene3Di2.60.120.10. 1 hit.
InterProiIPR032406. CLZ_dom.
IPR018490. cNMP-bd-like.
IPR018488. cNMP-bd_CS.
IPR000595. cNMP-bd_dom.
IPR005821. Ion_trans_dom.
IPR014710. RmlC-like_jellyroll.
[Graphical view]
PfamiPF16526. CLZ. 1 hit.
PF00027. cNMP_binding. 1 hit.
PF00520. Ion_trans. 1 hit.
[Graphical view]
SMARTiSM00100. cNMP. 1 hit.
[Graphical view]
SUPFAMiSSF51206. SSF51206. 1 hit.
PROSITEiPS00888. CNMP_BINDING_1. 1 hit.
PS00889. CNMP_BINDING_2. 1 hit.
PS50042. CNMP_BINDING_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9QWN7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHQMETSTMV QDNRVSRFII SIRAWAARHL HHEDPTPDSF LDRFHGAEPK
60 70 80 90 100
EVSSQERNAQ PNPGGQEPPE GGKGRKKDPI VVDPSSNIYY RWLTAIALPV
110 120 130 140 150
FYNWCLLVCR ACFDELQSEH LTLWLVLDYS ADALYVVDML VRARTGFLEQ
160 170 180 190 200
GLMVRDTKRL WKHYTKTLHF KLDILSLIPT DLAYLKLGMN YPELRFNRLL
210 220 230 240 250
RFSRLFEFFD RTETRTNYPN VFRIGNLVLY TLIIIHWNAC IYFAISKFIG
260 270 280 290 300
FGTDSWVYPN TSKPEYGRLS RKYIYSLYWS TLTLTTIGET PPPVKDEEYL
310 320 330 340 350
FVVIDFLVGV LIFATIVGNV GSMISNMNAS RAEFQAKIDS IKQYMQFRKV
360 370 380 390 400
TKDLETRVIR WFDYLWANRK TVDEKEVLKN LPDKLKAEIA INVHLDTLKK
410 420 430 440 450
VRIFQDCEAG LLVELVLKLR PAVFSPGDYI CKKGDIGREM YIIKEGKLAV
460 470 480 490 500
VADDGVTQFV VLSDGSYFGE ISILNIKGSK SGNRRTANIR SIGYSDLFCL
510 520 530 540 550
SKDDLMETLT EYPDAKRALE EKGRQILMKD NLIDDDLVTA RADARNIEEK
560 570 580 590 600
VEYLESSLDG LQTRFARLLA EYSASQMKLK QRLSQLESQM TRRGHGFSPD
610
RENSEDASKA D
Length:611
Mass (Da):70,400
Last modified:May 1, 2000 - v1
Checksum:i9ACECEF9EEF63AC4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB002801 mRNA. Translation: BAA24353.1.
RefSeqiNP_445947.1. NM_053495.1.
UniGeneiRn.10886.

Genome annotation databases

GeneIDi85257.
KEGGirno:85257.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB002801 mRNA. Translation: BAA24353.1.
RefSeqiNP_445947.1. NM_053495.1.
UniGeneiRn.10886.

3D structure databases

ProteinModelPortaliQ9QWN7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000056459.

Proteomic databases

PaxDbiQ9QWN7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi85257.
KEGGirno:85257.

Organism-specific databases

CTDi1261.
RGDi70948. Cnga3.

Phylogenomic databases

eggNOGiKOG0500. Eukaryota.
ENOG410YWWI. LUCA.
HOVERGENiHBG000281.
KOiK04950.

Gene expression databases

GenevisibleiQ9QWN7. RN.

Family and domain databases

Gene3Di2.60.120.10. 1 hit.
InterProiIPR032406. CLZ_dom.
IPR018490. cNMP-bd-like.
IPR018488. cNMP-bd_CS.
IPR000595. cNMP-bd_dom.
IPR005821. Ion_trans_dom.
IPR014710. RmlC-like_jellyroll.
[Graphical view]
PfamiPF16526. CLZ. 1 hit.
PF00027. cNMP_binding. 1 hit.
PF00520. Ion_trans. 1 hit.
[Graphical view]
SMARTiSM00100. cNMP. 1 hit.
[Graphical view]
SUPFAMiSSF51206. SSF51206. 1 hit.
PROSITEiPS00888. CNMP_BINDING_1. 1 hit.
PS00889. CNMP_BINDING_2. 1 hit.
PS50042. CNMP_BINDING_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9QWN7_RAT
AccessioniPrimary (citable) accession number: Q9QWN7
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: November 30, 2016
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.