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Protein
Submitted name:

Cyclic nucleotide-gated channel

Gene

Cnga3

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • cGMP binding Source: RGD
  • intracellular cGMP activated cation channel activity Source: RGD
  • signal transducer activity Source: RGD

GO - Biological processi

  • ion transmembrane transport Source: RGD
  • response to cAMP Source: RGD
  • response to corticosteroid Source: RGD
  • response to magnesium ion Source: RGD

Keywordsi

Molecular functionIon channelSAAS annotation
Biological processIon transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Cyclic nucleotide-gated channelImported
Gene namesi
Name:Cnga3Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi70948 Cnga3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei227 – 245HelicalSequence analysisAdd BLAST19
Transmembranei299 – 321HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

GenevisibleiQ9QWN7 RN

Structurei

3D structure databases

ProteinModelPortaliQ9QWN7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini403 – 517Cyclic nucleotide-bindingInterPro annotationAdd BLAST115

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili544 – 564Sequence analysisAdd BLAST21
Coiled coili569 – 589Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG0500 Eukaryota
ENOG410YWWI LUCA
HOVERGENiHBG000281
KOiK04950

Family and domain databases

CDDicd00038 CAP_ED, 1 hit
Gene3Di2.60.120.10, 1 hit
InterProiView protein in InterPro
IPR032406 CLZ_dom
IPR018490 cNMP-bd-like
IPR018488 cNMP-bd_CS
IPR000595 cNMP-bd_dom
IPR005821 Ion_trans_dom
IPR014710 RmlC-like_jellyroll
PfamiView protein in Pfam
PF16526 CLZ, 1 hit
PF00027 cNMP_binding, 1 hit
PF00520 Ion_trans, 1 hit
SMARTiView protein in SMART
SM00100 cNMP, 1 hit
SUPFAMiSSF51206 SSF51206, 1 hit
PROSITEiView protein in PROSITE
PS00888 CNMP_BINDING_1, 1 hit
PS00889 CNMP_BINDING_2, 1 hit
PS50042 CNMP_BINDING_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q9QWN7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHQMETSTMV QDNRVSRFII SIRAWAARHL HHEDPTPDSF LDRFHGAEPK
60 70 80 90 100
EVSSQERNAQ PNPGGQEPPE GGKGRKKDPI VVDPSSNIYY RWLTAIALPV
110 120 130 140 150
FYNWCLLVCR ACFDELQSEH LTLWLVLDYS ADALYVVDML VRARTGFLEQ
160 170 180 190 200
GLMVRDTKRL WKHYTKTLHF KLDILSLIPT DLAYLKLGMN YPELRFNRLL
210 220 230 240 250
RFSRLFEFFD RTETRTNYPN VFRIGNLVLY TLIIIHWNAC IYFAISKFIG
260 270 280 290 300
FGTDSWVYPN TSKPEYGRLS RKYIYSLYWS TLTLTTIGET PPPVKDEEYL
310 320 330 340 350
FVVIDFLVGV LIFATIVGNV GSMISNMNAS RAEFQAKIDS IKQYMQFRKV
360 370 380 390 400
TKDLETRVIR WFDYLWANRK TVDEKEVLKN LPDKLKAEIA INVHLDTLKK
410 420 430 440 450
VRIFQDCEAG LLVELVLKLR PAVFSPGDYI CKKGDIGREM YIIKEGKLAV
460 470 480 490 500
VADDGVTQFV VLSDGSYFGE ISILNIKGSK SGNRRTANIR SIGYSDLFCL
510 520 530 540 550
SKDDLMETLT EYPDAKRALE EKGRQILMKD NLIDDDLVTA RADARNIEEK
560 570 580 590 600
VEYLESSLDG LQTRFARLLA EYSASQMKLK QRLSQLESQM TRRGHGFSPD
610
RENSEDASKA D
Length:611
Mass (Da):70,400
Last modified:May 1, 2000 - v1
Checksum:i9ACECEF9EEF63AC4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB002801 mRNA Translation: BAA24353.1
RefSeqiNP_445947.1, NM_053495.1
UniGeneiRn.10886

Genome annotation databases

GeneIDi85257
KEGGirno:85257

Similar proteinsi

Entry informationi

Entry nameiQ9QWN7_RAT
AccessioniPrimary (citable) accession number: Q9QWN7
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: May 23, 2018
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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