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Q9QUN4

- Q9QUN4_RAT

UniProt

Q9QUN4 - Q9QUN4_RAT

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Protein
Submitted name:

Pancreatic lipase

Gene

Pnlip

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei169 – 1691NucleophileUniRule annotation
Active sitei193 – 1931Charge relay systemUniRule annotation
Active sitei280 – 2801Charge relay systemUniRule annotation

GO - Molecular functioni

  1. triglyceride lipase activity Source: InterPro

GO - Biological processi

  1. lipid metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Pancreatic lipaseImported
Gene namesi
Name:PnlipImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi3360. Pnlip.

Subcellular locationi

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

SecretedSAAS annotation

Expressioni

Gene expression databases

GenevestigatoriQ9QUN4.

Family & Domainsi

Sequence similaritiesi

Belongs to the AB hydrolase superfamily. Lipase family.UniRule annotation

Phylogenomic databases

HOVERGENiHBG003243.

Family and domain databases

Gene3Di2.60.60.20. 1 hit.
3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR000734. Lipase.
IPR008976. Lipase_LipOase.
IPR013818. Lipase_N.
IPR002331. Lipase_panc.
IPR016272. Lipoprotein_lipase_LIPH.
IPR001024. PLAT/LH2_dom.
[Graphical view]
PANTHERiPTHR11610. PTHR11610. 1 hit.
PfamiPF00151. Lipase. 1 hit.
PF01477. PLAT. 1 hit.
[Graphical view]
PIRSFiPIRSF000865. Lipoprotein_lipase_LIPH. 1 hit.
PRINTSiPR00823. PANCLIPASE.
PR00821. TAGLIPASE.
SMARTiSM00308. LH2. 1 hit.
[Graphical view]
SUPFAMiSSF49723. SSF49723. 1 hit.
SSF53474. SSF53474. 1 hit.
PROSITEiPS50095. PLAT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q9QUN4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLMLWTFAVL LGAVAGKEVC FDKLGCFSDD APWSGTIDRP LKALPWSPAQ
60 70 80 90 100
INTRFLLYTN ENQDNYQKIT SDASSIRNSN FKTNRKTRII IHGFIDKGEE
110 120 130 140 150
NWLSDMCKNM FKVESVNCIC VDWKGGSRAT YTQATQNVRV VGAEVALLVN
160 170 180 190 200
VLKSDLGYSP DNVHLIGHSL GSHVAGEAGK RTFGAIGRIT GLDAAEPYFQ
210 220 230 240 250
GTPEEVRLDP TDAQFVDAIH TDAAPIIPNL GFGMSQTVGH LDFFPNGGME
260 270 280 290 300
MPGCQKNILS QIVDIDGIWE GTRDFAACNH LRSYKYYTDS IVNPTGFSGF
310 320 330 340 350
SCSSYNVFSA NKCFPCGSEG CPQMGHYADK YPGKTKELYQ KFYLNTGDKS
360 370 380 390 400
NFARWRYQVT VTLSGQKVTG HILVSLFGNG GNSKQYEVFK GSLHPGDTHV
410 420 430 440 450
KEFDSDMDVG DLQKVKFIWY NNVINPTLPK VGASRISVER NDGRVFNFCS

Q
Length:451
Mass (Da):49,939
Last modified:May 1, 2000 - v1
Checksum:i65D19706B5D5B732
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei451 – 4511Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D88534 mRNA. Translation: BAA13637.1.
D88535 mRNA. Translation: BAA13638.1.
UniGeneiRn.10130.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D88534 mRNA. Translation: BAA13637.1 .
D88535 mRNA. Translation: BAA13638.1 .
UniGenei Rn.10130.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

RGDi 3360. Pnlip.

Phylogenomic databases

HOVERGENi HBG003243.

Gene expression databases

Genevestigatori Q9QUN4.

Family and domain databases

Gene3Di 2.60.60.20. 1 hit.
3.40.50.1820. 1 hit.
InterProi IPR029058. AB_hydrolase.
IPR000734. Lipase.
IPR008976. Lipase_LipOase.
IPR013818. Lipase_N.
IPR002331. Lipase_panc.
IPR016272. Lipoprotein_lipase_LIPH.
IPR001024. PLAT/LH2_dom.
[Graphical view ]
PANTHERi PTHR11610. PTHR11610. 1 hit.
Pfami PF00151. Lipase. 1 hit.
PF01477. PLAT. 1 hit.
[Graphical view ]
PIRSFi PIRSF000865. Lipoprotein_lipase_LIPH. 1 hit.
PRINTSi PR00823. PANCLIPASE.
PR00821. TAGLIPASE.
SMARTi SM00308. LH2. 1 hit.
[Graphical view ]
SUPFAMi SSF49723. SSF49723. 1 hit.
SSF53474. SSF53474. 1 hit.
PROSITEi PS50095. PLAT. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Direct evidence that alkaline lipase from Rat brain is the same enzyme as pancreatic lipase from Rat Pancreas."
    Tsujita T., Sumida M., Sumiyoshi M., Kameda K., Okuda H.
    Submitted (OCT-1996) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Wistar-KingImported.
    Tissue: PancreasImported.
  2. Sumida M.
    Submitted (OCT-1996) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Wistar-KingImported.
  3. "Direct evidence that alkaline lipase from Rat brain is the same enzyme as pancreatic lipase from Rat Pancreas."
    Takahiro T.
    Submitted (MAR-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Wistar-KingImported.

Entry informationi

Entry nameiQ9QUN4_RAT
AccessioniPrimary (citable) accession number: Q9QUN4
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: October 29, 2014
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)