Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q9QUN4

- Q9QUN4_RAT

UniProt

Q9QUN4 - Q9QUN4_RAT

Protein
Submitted name:

Pancreatic lipase

Gene

Pnlip

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 85 (01 Oct 2014)
      Sequence version 1 (01 May 2000)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei169 – 1691NucleophileUniRule annotation
    Active sitei193 – 1931Charge relay systemUniRule annotation
    Active sitei280 – 2801Charge relay systemUniRule annotation

    GO - Molecular functioni

    1. triglyceride lipase activity Source: InterPro

    GO - Biological processi

    1. lipid metabolic process Source: InterPro

    Keywords - Molecular functioni

    HydrolaseUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Pancreatic lipaseImported
    Gene namesi
    Name:PnlipImported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

    Organism-specific databases

    RGDi3360. Pnlip.

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-KW

    Keywords - Cellular componenti

    SecretedSAAS annotation

    Expressioni

    Gene expression databases

    GenevestigatoriQ9QUN4.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the AB hydrolase superfamily. Lipase family.UniRule annotation

    Phylogenomic databases

    HOVERGENiHBG003243.
    InParanoidiQ9QUN4.

    Family and domain databases

    Gene3Di2.60.60.20. 1 hit.
    3.40.50.1820. 1 hit.
    InterProiIPR029058. AB_hydrolase.
    IPR000734. Lipase.
    IPR008976. Lipase_LipOase.
    IPR013818. Lipase_N.
    IPR002331. Lipase_panc.
    IPR016272. Lipoprotein_lipase_LIPH.
    IPR001024. PLAT/LH2_dom.
    [Graphical view]
    PANTHERiPTHR11610. PTHR11610. 1 hit.
    PfamiPF00151. Lipase. 1 hit.
    PF01477. PLAT. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000865. Lipoprotein_lipase_LIPH. 1 hit.
    PRINTSiPR00823. PANCLIPASE.
    PR00821. TAGLIPASE.
    SMARTiSM00308. LH2. 1 hit.
    [Graphical view]
    SUPFAMiSSF49723. SSF49723. 1 hit.
    SSF53474. SSF53474. 1 hit.
    PROSITEiPS50095. PLAT. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q9QUN4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLMLWTFAVL LGAVAGKEVC FDKLGCFSDD APWSGTIDRP LKALPWSPAQ    50
    INTRFLLYTN ENQDNYQKIT SDASSIRNSN FKTNRKTRII IHGFIDKGEE 100
    NWLSDMCKNM FKVESVNCIC VDWKGGSRAT YTQATQNVRV VGAEVALLVN 150
    VLKSDLGYSP DNVHLIGHSL GSHVAGEAGK RTFGAIGRIT GLDAAEPYFQ 200
    GTPEEVRLDP TDAQFVDAIH TDAAPIIPNL GFGMSQTVGH LDFFPNGGME 250
    MPGCQKNILS QIVDIDGIWE GTRDFAACNH LRSYKYYTDS IVNPTGFSGF 300
    SCSSYNVFSA NKCFPCGSEG CPQMGHYADK YPGKTKELYQ KFYLNTGDKS 350
    NFARWRYQVT VTLSGQKVTG HILVSLFGNG GNSKQYEVFK GSLHPGDTHV 400
    KEFDSDMDVG DLQKVKFIWY NNVINPTLPK VGASRISVER NDGRVFNFCS 450
    Q 451
    Length:451
    Mass (Da):49,939
    Last modified:May 1, 2000 - v1
    Checksum:i65D19706B5D5B732
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei451 – 4511Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D88534 mRNA. Translation: BAA13637.1.
    D88535 mRNA. Translation: BAA13638.1.
    UniGeneiRn.10130.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D88534 mRNA. Translation: BAA13637.1 .
    D88535 mRNA. Translation: BAA13638.1 .
    UniGenei Rn.10130.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    RGDi 3360. Pnlip.

    Phylogenomic databases

    HOVERGENi HBG003243.
    InParanoidi Q9QUN4.

    Gene expression databases

    Genevestigatori Q9QUN4.

    Family and domain databases

    Gene3Di 2.60.60.20. 1 hit.
    3.40.50.1820. 1 hit.
    InterProi IPR029058. AB_hydrolase.
    IPR000734. Lipase.
    IPR008976. Lipase_LipOase.
    IPR013818. Lipase_N.
    IPR002331. Lipase_panc.
    IPR016272. Lipoprotein_lipase_LIPH.
    IPR001024. PLAT/LH2_dom.
    [Graphical view ]
    PANTHERi PTHR11610. PTHR11610. 1 hit.
    Pfami PF00151. Lipase. 1 hit.
    PF01477. PLAT. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000865. Lipoprotein_lipase_LIPH. 1 hit.
    PRINTSi PR00823. PANCLIPASE.
    PR00821. TAGLIPASE.
    SMARTi SM00308. LH2. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49723. SSF49723. 1 hit.
    SSF53474. SSF53474. 1 hit.
    PROSITEi PS50095. PLAT. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Direct evidence that alkaline lipase from Rat brain is the same enzyme as pancreatic lipase from Rat Pancreas."
      Tsujita T., Sumida M., Sumiyoshi M., Kameda K., Okuda H.
      Submitted (OCT-1996) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: Wistar-KingImported.
      Tissue: PancreasImported.
    2. Sumida M.
      Submitted (OCT-1996) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: Wistar-KingImported.
    3. "Direct evidence that alkaline lipase from Rat brain is the same enzyme as pancreatic lipase from Rat Pancreas."
      Takahiro T.
      Submitted (MAR-1997) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: Wistar-KingImported.

    Entry informationi

    Entry nameiQ9QUN4_RAT
    AccessioniPrimary (citable) accession number: Q9QUN4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 1, 2000
    Last sequence update: May 1, 2000
    Last modified: October 1, 2014
    This is version 85 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)