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Protein
Submitted name:

Basic-helix-loop-helix protein (BHLH)

Gene

Hey1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Basic-helix-loop-helix protein (BHLH)Imported
Submitted name:
Brain cDNA, clone MNCb-2686, similar to Mus musculus hairy/enhancer-of-split related with YRPW motif1(Hey1), mRNAImported
Submitted name:
Cardiovascular helix-loop-helix factor 2Imported
Submitted name:
HES-related repressor protein 2 HERP2Imported
Submitted name:
Hairy-related transcription factor 1Imported
Submitted name:
Hairy/enhancer-of-split related with YRPW motif 1Imported
Submitted name:
Hairy/enhancer-of-split related with YRPW motif 1, isoform CRA_aImported
Submitted name:
Hairy/enhancer-of-split-related with YRPW motif protein 1Imported
Gene namesi
Name:Hey1Imported
Synonyms:Hrt1Imported
ORF Names:mCG_10136Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 3

Organism-specific databases

MGIiMGI:1341800. Hey1.

Subcellular locationi

  • Nucleus SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000040289.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000038014.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini49 – 10456BHLH (basic helix-loop-helix)InterPro annotationAdd
BLAST
Domaini122 – 15837OrangeInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 1 basic helix-loop-helix (bHLH) domain.UniRule annotation
Contains Orange domain.SAAS annotation
Contains bHLH (basic helix-loop-helix) domain.SAAS annotation

Phylogenomic databases

eggNOGiKOG4304. Eukaryota.
ENOG4111F0X. LUCA.
GeneTreeiENSGT00700000104130.
HOVERGENiHBG003275.
KOiK09091.
OMAiIPWGTAF.
OrthoDBiEOG091G0HWC.
TreeFamiTF323617.

Family and domain databases

Gene3Di4.10.280.10. 1 hit.
InterProiIPR011598. bHLH_dom.
IPR003650. Orange_dom.
[Graphical view]
PfamiPF07527. Hairy_orange. 1 hit.
PF00010. HLH. 1 hit.
[Graphical view]
SMARTiSM00353. HLH. 1 hit.
SM00511. ORANGE. 1 hit.
[Graphical view]
SUPFAMiSSF47459. SSF47459. 1 hit.
PROSITEiPS50888. BHLH. 1 hit.
PS51054. ORANGE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9QUM5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKRAHPDYSS SDSELDETIE VEKESADENG NLSSALCSMS PTTSSQVLAR
60 70 80 90 100
KRRRGIIEKR RRDRINNSLS ELRRLVPSAF EKQGSAKLEK AEILQMTVDH
110 120 130 140 150
LKMLHTAGGK GYFDAHALAM DYRSLGFREC LAEVARYLSI IEGLDASDPL
160 170 180 190 200
RVRLVSHLNN YASQREAASG AHGGLGHIPW GSAFGHHPHI AHPLLLPQNG
210 220 230 240 250
HGNAGTAASP TEPHHQGRLA SAHPEAPALR APPSGGLGPV LPVVTSASKL
260 270 280 290
SPPLLSSVAS LSAFPFSFSS FHLLSPSTPT QAANLGKPYR PWGTEIGAF
Length:299
Mass (Da):32,106
Last modified:May 1, 2000 - v1
Checksum:i77110233BC98A1AE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC132225 Genomic DNA. No translation available.
AF176423 mRNA. Translation: AAD51750.1.
AF172286 mRNA. Translation: AAF14545.1.
AF232241 mRNA. Translation: AAF37299.1.
BC086635 mRNA. Translation: AAH86635.1.
AB041590 mRNA. Translation: BAA95073.1.
AK140212 mRNA. Translation: BAE24283.1.
AJ243895 mRNA. Translation: CAB51321.1.
CH466577 Genomic DNA. Translation: EDL05197.1.
RefSeqiNP_034553.2. NM_010423.2.
UniGeneiMm.29581.

Genome annotation databases

EnsembliENSMUST00000042412; ENSMUSP00000038014; ENSMUSG00000040289.
GeneIDi15213.
KEGGimmu:15213.
UCSCiuc008oop.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC132225 Genomic DNA. No translation available.
AF176423 mRNA. Translation: AAD51750.1.
AF172286 mRNA. Translation: AAF14545.1.
AF232241 mRNA. Translation: AAF37299.1.
BC086635 mRNA. Translation: AAH86635.1.
AB041590 mRNA. Translation: BAA95073.1.
AK140212 mRNA. Translation: BAE24283.1.
AJ243895 mRNA. Translation: CAB51321.1.
CH466577 Genomic DNA. Translation: EDL05197.1.
RefSeqiNP_034553.2. NM_010423.2.
UniGeneiMm.29581.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000038014.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000042412; ENSMUSP00000038014; ENSMUSG00000040289.
GeneIDi15213.
KEGGimmu:15213.
UCSCiuc008oop.1. mouse.

Organism-specific databases

CTDi23462.
MGIiMGI:1341800. Hey1.

Phylogenomic databases

eggNOGiKOG4304. Eukaryota.
ENOG4111F0X. LUCA.
GeneTreeiENSGT00700000104130.
HOVERGENiHBG003275.
KOiK09091.
OMAiIPWGTAF.
OrthoDBiEOG091G0HWC.
TreeFamiTF323617.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000040289.

Family and domain databases

Gene3Di4.10.280.10. 1 hit.
InterProiIPR011598. bHLH_dom.
IPR003650. Orange_dom.
[Graphical view]
PfamiPF07527. Hairy_orange. 1 hit.
PF00010. HLH. 1 hit.
[Graphical view]
SMARTiSM00353. HLH. 1 hit.
SM00511. ORANGE. 1 hit.
[Graphical view]
SUPFAMiSSF47459. SSF47459. 1 hit.
PROSITEiPS50888. BHLH. 1 hit.
PS51054. ORANGE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9QUM5_MOUSE
AccessioniPrimary (citable) accession number: Q9QUM5
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: September 7, 2016
This is version 130 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.