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Protein
Submitted name:

MCG15083

Gene

Try5

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protease, Serine proteaseUniRule annotation

Enzyme and pathway databases

ReactomeiR-MMU-1442490 Collagen degradation
R-MMU-1592389 Activation of Matrix Metalloproteinases
R-MMU-196741 Cobalamin (Cbl, vitamin B12) transport and metabolism
R-MMU-6798695 Neutrophil degranulation
R-MMU-6803157 Antimicrobial peptides

Protein family/group databases

MEROPSiS01.057

Names & Taxonomyi

Protein namesi
Submitted name:
MCG15083Imported
Submitted name:
TESP4Imported
Submitted name:
Trypsin 5Imported
Submitted name:
Trypsinogen 9Imported
Gene namesi
Name:Try5Imported
Synonyms:1810049H19RikImported, trypsinogenImported
ORF Names:mCG_15083Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 6

Organism-specific databases

MGIiMGI:102756 Try5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 15Sequence analysisAdd BLAST15
ChainiPRO_501458949116 – 246Sequence analysisAdd BLAST231

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000036938

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000064498

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini24 – 244Peptidase S1InterPro annotationAdd BLAST221

Sequence similaritiesi

Belongs to the peptidase S1 family.SAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3627 Eukaryota
COG5640 LUCA
GeneTreeiENSGT00760000118862
HOGENOMiHOG000251820
HOVERGENiHBG013304
KOiK01312
OMAiCALKRRP
OrthoDBiEOG091G0DF7

Family and domain databases

CDDicd00190 Tryp_SPc, 1 hit
InterProiView protein in InterPro
IPR009003 Peptidase_S1_PA
IPR001314 Peptidase_S1A
IPR001254 Trypsin_dom
IPR018114 TRYPSIN_HIS
IPR033116 TRYPSIN_SER
PfamiView protein in Pfam
PF00089 Trypsin, 1 hit
PRINTSiPR00722 CHYMOTRYPSIN
SMARTiView protein in SMART
SM00020 Tryp_SPc, 1 hit
SUPFAMiSSF50494 SSF50494, 1 hit
PROSITEiView protein in PROSITE
PS50240 TRYPSIN_DOM, 1 hit
PS00134 TRYPSIN_HIS, 1 hit
PS00135 TRYPSIN_SER, 1 hit

Sequencei

Sequence statusi: Complete.

Q9QUK9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSLLFLALV GAAVAFPVDD DDKIVGGYTC RENSIPYQVS LNSGYHFCGG
60 70 80 90 100
SLINDQWVVS AAHCYKTRIQ VRLGEHNINV LEGNEQFVNS AKIIKHPNFN
110 120 130 140 150
SRTLNNDIML IKLASPVTLN ARVATVALPS SCAPAGTQCL ISGWGNTLSF
160 170 180 190 200
GVNNPDLLQC LDAPLLPQAD CEASYPGKIT NNMICVGFLE GGKDSCQGDS
210 220 230 240
GGPVVCNGQL QGIVSWGYGC ALKDNPGVYT KVCNYVDWIQ DTIAAN
Length:246
Mass (Da):26,277
Last modified:May 1, 2000 - v1
Checksum:i915C92353EC42809
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC125228 Genomic DNA No translation available.
AE000664 Genomic DNA Translation: AAB69057.1
BC139220 mRNA Translation: AAI39221.1
BC139223 mRNA Translation: AAI39224.1
AB017031 Genomic DNA Translation: BAA74760.1
AB009661 mRNA Translation: BAA85187.1
AK007843 mRNA Translation: BAB25300.1
AK160484 mRNA Translation: BAE35815.1
CH466533 Genomic DNA Translation: EDL13536.1
RefSeqiNP_001003405.1, NM_001003405.4
UniGeneiMm.333022

Genome annotation databases

EnsembliENSMUST00000064324; ENSMUSP00000064498; ENSMUSG00000036938
GeneIDi103964
KEGGimmu:103964
UCSCiuc009bot.2 mouse

Similar proteinsi

Entry informationi

Entry nameiQ9QUK9_MOUSE
AccessioniPrimary (citable) accession number: Q9QUK9
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: May 23, 2018
This is version 149 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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