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Protein

Heat shock protein beta-7

Gene

Hspb7

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  • response to heat Source: RGD

Keywordsi

Molecular functionChaperone
Biological processStress response

Names & Taxonomyi

Protein namesi
Recommended name:
Heat shock protein beta-7
Short name:
HspB7
Alternative name(s):
Cardiovascular heat shock protein
Short name:
cvHsp
Gene namesi
Name:Hspb7
Synonyms:Cvhsp
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi62021 Hspb7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000125943‹1 – ›90Heat shock protein beta-7Add BLAST›90

Proteomic databases

PaxDbiQ9QUK5

Expressioni

Tissue specificityi

Found in both cardiac and skeletal muscle.

Interactioni

Subunit structurei

Interacts with C-terminal domain of actin-binding protein 280.By similarity

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000042240

Structurei

3D structure databases

SMRiQ9QUK5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini39 – ›90sHSPPROSITE-ProRule annotationAdd BLAST›52

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi1 – 8Poly-Ser8

Sequence similaritiesi

Belongs to the small heat shock protein (HSP20) family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG3591 Eukaryota
ENOG410YERS LUCA
InParanoidiQ9QUK5

Family and domain databases

Gene3Di2.60.40.790, 1 hit
InterProiView protein in InterPro
IPR002068 A-crystallin/Hsp20_dom
IPR031107 HSP20
IPR008978 HSP20-like_chaperone
PANTHERiPTHR11527 PTHR11527, 1 hit
PfamiView protein in Pfam
PF00011 HSP20, 1 hit
SUPFAMiSSF49764 SSF49764, 1 hit
PROSITEiView protein in PROSITE
PS01031 SHSP, 1 hit

Sequencei

Sequence statusi: Fragment.

Q9QUK5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
SSSSSSASRA LPAQDPPMEK ALSMFSEDFG SFMLPHSEPL TFPARPGGQG
60 70 80 90
NIKTLGDAYE FTVDMRDFSP EDIIVTTSNN HIEVRAEKKP
Length:90
Mass (Da):9,804
Last modified:May 1, 2000 - v1
Checksum:i9D122DB6443ED1FE
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei11
Non-terminal residuei901

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ243193 mRNA Translation: CAB63268.1
AF155910 mRNA Translation: AAF20024.1
UniGeneiRn.21809

Genome annotation databases

UCSCiRGD:62021 rat

Entry informationi

Entry nameiHSPB7_RAT
AccessioniPrimary (citable) accession number: Q9QUK5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: May 1, 2000
Last modified: May 23, 2018
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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