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Protein
Submitted name:

Cell surface glycoprotein

Gene

MHC II H2-IE-beta

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Enzyme and pathway databases

ReactomeiREACT_280649. Downstream TCR signaling.
REACT_309115. PD-1 signaling.
REACT_316383. MHC class II antigen presentation.
REACT_334692. Generation of second messenger molecules.
REACT_345130. Translocation of ZAP-70 to Immunological synapse.
REACT_345471. Phosphorylation of CD3 and TCR zeta chains.
REACT_349056. Interferon gamma signaling.

Names & Taxonomyi

Protein namesi
Submitted name:
Cell surface glycoproteinImported
Gene namesi
Name:MHC II H2-IE-betaImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Expressioni

Gene expression databases

BgeeiQ9QUH8.
ExpressionAtlasiQ9QUH8. baseline and differential.
GenevestigatoriQ9QUH8.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000075654.

Family & Domainsi

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
[Graphical view]
PfamiPF07654. C1-set. 1 hit.
[Graphical view]
SMARTiSM00407. IGc1. 1 hit.
[Graphical view]
PROSITEiPS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q9QUH8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
EPTVTVYPTK TQPLEHHNLL VCSVSDFYPG NIEVRWFRNG KEEKTGIVST
60 70 80 90
GLVRNGDWTF QTLVMLETVP QSGEVYTCQV EHPSLTDPVT VEW
Length:93
Mass (Da):10,564
Last modified:May 1, 2000 - v1
Checksum:iCA9CC8B6D9F67256
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei93 – 931Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M14234 Genomic DNA. Translation: AAA39640.1.
M14235 Genomic DNA. Translation: AAA39641.1.
M14236 Genomic DNA. Translation: AAA39642.1.
UniGeneiMm.22564.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M14234 Genomic DNA. Translation: AAA39640.1.
M14235 Genomic DNA. Translation: AAA39641.1.
M14236 Genomic DNA. Translation: AAA39642.1.
UniGeneiMm.22564.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000075654.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

ReactomeiREACT_280649. Downstream TCR signaling.
REACT_309115. PD-1 signaling.
REACT_316383. MHC class II antigen presentation.
REACT_334692. Generation of second messenger molecules.
REACT_345130. Translocation of ZAP-70 to Immunological synapse.
REACT_345471. Phosphorylation of CD3 and TCR zeta chains.
REACT_349056. Interferon gamma signaling.

Gene expression databases

BgeeiQ9QUH8.
ExpressionAtlasiQ9QUH8. baseline and differential.
GenevestigatoriQ9QUH8.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
[Graphical view]
PfamiPF07654. C1-set. 1 hit.
[Graphical view]
SMARTiSM00407. IGc1. 1 hit.
[Graphical view]
PROSITEiPS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Molecular analysis of the hotspot of recombination in the murine major histocompatibility complex."
    Kobori J.A., Strauss E., Minard K., Hood L.
    Science 234:173-179(1986) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: B10.AImported.

Entry informationi

Entry nameiQ9QUH8_MOUSE
AccessioniPrimary (citable) accession number: Q9QUH8
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: April 1, 2015
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.