DNA polymerase 037L

<p>Provides any useful information about the protein, mostly biological knowledge.</p><p><a href='../manual/function_section' target='_top'>More...</a></p>Functionⁱ

<p>Describes the catalytic activity of an enzyme, i.e. the chemical reaction it catalyzes. This information usually correlates with the presence of an EC (Enzyme Commission) number in the ‘Names and taxonomy’ section.</p><p><a href='../manual/catalytic_activity' target='_top'>More...</a></p>Catalytic activityⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• 3'-5' exonuclease activity Source: InterPro
• DNA binding Source: UniProtKB-KW
• DNA-directed DNA polymerase activity Source: UniProtKB-KW
• nucleotide binding Source: InterPro

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Biological processⁱ

• DNA replication Source: UniProtKB-KW

<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Molecular functionⁱ

<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Biological processⁱ

<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Ligandⁱ

<p>Provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.</p><p><a href='../manual/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

<p>Describes post-translational modifications (PTMs) and/or processing events.</p><p><a href='../manual/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	Length	Description	Graphical view	Feature identifier	Actions
<p>Describes the extent of a polypeptide chain in the mature protein following processing.</p><p><a href='../manual/chain' target='_top'>More...</a></p>Chaini	1 – 1273	1273	DNA polymerase 037L		PRO_0000376943	Add BLAST

Proteomic databases

<p>Provides information on the tertiary and secondary structure of a protein.</p><p><a href='../manual/structure_section' target='_top'>More...</a></p>Structureⁱ

3D structure databases

<p>Provides information on sequence similarities with other proteins and the domain(s) present in a protein.</p><p><a href='../manual/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Coiled coil

Feature key	Position(s)	Length	Description	Graphical view	Feature identifier	Actions
<p>Denotes the positions of regions of coiled coil within the protein.</p><p><a href='../manual/coiled' target='_top'>More...</a></p>Coiled coili	679 – 837	159	Sequence analysis			Add BLAST

<p>Provides information about the sequence similarity with other proteins.</p><p><a href='../manual/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesⁱ

<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

<p>Displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.</p><p><a href='../manual/sequences_section' target='_top'>More...</a></p>Sequenceⁱ

<p>Indicates if the <a href="/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.</p><p><a href='../manual/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

        10         20         30         40         50
MEKTMFAYSW HQTDDETKNW SKSKESLRIY GITDDGKTIC LIVNDFKPFV 
        60         70         80         90        100
HVELPSSINW RQKIGGQPKV QKIMDYLNFI LGDLKPVKNR TIFIDKYKLY 
       110        120        130        140        150
GSNYVQTSPG VFQRKKFPYL VLFFESRKHI KNLEYKLKNT VDVPGFGKIK 
       160        170        180        190        200
LNVRETNVSP ILQLCVERNL PSAGWIGFKV EGRGALAGYG ELVEEKKKFT 
       210        220        230        240        250
DCDEEYVISK NYIYSIDKHV PVKAKVMAWD IEVYSEDGNF PDAMKPGNVV 
       260        270        280        290        300
FQISCIFFIV GTSYKQKYLL TLGDPLEYTT TPINEEGCGK DTIVCKFKTE 
       310        320        330        340        350
EDLIIAFSSL QKREKPHITT GWNIFNFDTT FLLKRAKLHR CLPNFLLQGF 
       360        370        380        390        400
PKDQLGKEKE IKWQSKAYGT TDLKFIDCEG ILCIDLMDVV QKEHKLDSYS 
       410        420        430        440        450
LNFVAKHFLG SKKDDLKPKE IFICYREGIK KEVKNIVIHP LSNNLNIYLG 
       460        470        480        490        500
KEEIMIENKK FKKPLKPFFR IQNTGKLVSD EDDSVFHVNY RGEVFSFLIA 
       510        520        530        540        550
VHNEEKYEIK TVSEFNNYKN AYGTYTLSAQ KAMAKVGKYC VQDSVLVADI 
       560        570        580        590        600
FEHLQTWLSF SEMSRTCTTP IMTIHVHGQQ VKFFNQVYKY CYDHKTVTDK 
       610        620        630        640        650
ETYKVDEKER YRGAEVFDPV PGLKRNVVPL DFASLYPSLI IARNMCYSTF 
       660        670        680        690        700
VDNDDIPDEM CHVMEWDDHV ACSHDPKVIR KNAITEELEK LKKIANAKKM 
       710        720        730        740        750
YTQGTRTYKK MMCSYLVMEN TKEKTEMSKH LKDLDRENNE LLNIVNKQTP 
       760        770        780        790        800
GYIESIKKKI SDLTSERSEI TKKLSKSVMC VSNRRYRFLK EPKGILPTII 
       810        820        830        840        850
QNLLDARKNT RTEIKNYKSR LALLMEKENK SKEDIDEITS IENLLPILDK 
       860        870        880        890        900
RQNSYKISAN SMYGATGVRV GALPFMPIAM CTTYMGRKSI VEVSQYLKEL 
       910        920        930        940        950
GGRVVYGDTD SNYVTFDDVV DKNVKVGTEE FSREMKKLWN HAIEIAKTIS 
       960        970        980        990       1000
KKFDNPITLE FENAIYFKFL ILTKKRYMYY TCGKDGNILM DANGKPKMGQ 
      1010       1020       1030       1040       1050
RGVILSRRDN CKYMKDVYAN VIDKIFDEQS ENEILNGVVE KMLNLYTRQI 
      1060       1070       1080       1090       1100
EFTSCEKDEN YLKNLIVTKS VGDYGGDKAT FEPILGKNEK GEDKWKIGNY 
      1110       1120       1130       1140       1150
VVPLITDEII KTCGTNGLPM TQNEIKDWYL ERLPCQVQLE VKIKRRGHNK 
      1160       1170       1180       1190       1200
EEGQRLSYVV TDIGCKGKQS EKIESVEYFK THSKVLKLDY GYYIERLIEP 
      1210       1220       1230       1240       1250
LDQVFQAVFK NCQEKETIYS DNFRKTKLFS IFEKRGKHSQ ANFTKELHKL 
      1260       1270 
CSVTKPKLIN EIKSFSKPDL VFV                       

Sequence databases

Genome annotation databases

<p>Is used to point to information related to entries and found in data collections other than UniProtKB.</p><p><a href='../manual/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Family and domain databases

<p>Provides general information on the entry.</p><p><a href='../manual/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>Contains any relevant information that doesn’t fit in any other defined sections</p><p><a href='../manual/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termⁱ

Documents

1. SIMILARITY comments
   Index of protein domains and families

<p>Provides links to the UniProt Reference Clusters (<a href="/help/uniref">UniRef</a>). UniRef consists of clusters for UniProtKB sequences (including isoforms) and selected UniParc sequences, in order to obtain complete coverage of the sequence space at resolutions of 100%, 90% and 50% identity.</p><p><a href='../manual/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ