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Q9QSK2

- DPOL_IIV6

UniProt

Q9QSK2 - DPOL_IIV6

Protein

DNA polymerase 037L

Gene

DPOL

Organism
Invertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 72 (01 Oct 2014)
      Sequence version 1 (01 May 2000)
      Previous versions | rss
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    Functioni

    DNA-directed DNA polymerase involved in viral DNA replication.

    Catalytic activityi

    Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW
    2. DNA-directed DNA polymerase activity Source: UniProtKB-KW
    3. nucleotide binding Source: InterPro

    Keywords - Molecular functioni

    DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase

    Keywords - Biological processi

    DNA replication

    Keywords - Ligandi

    DNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA polymerase 037L (EC:2.7.7.7)
    Gene namesi
    Name:DPOL
    ORF Names:IIV6-037L
    OrganismiInvertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus)
    Taxonomic identifieri176652 [NCBI]
    Taxonomic lineageiVirusesdsDNA viruses, no RNA stageIridoviridaeIridovirus
    Virus hostiAcheta domesticus (House cricket) [TaxID: 6997]
    Chilo suppressalis (striped riceborer) [TaxID: 168631]
    Gryllus bimaculatus (Two-spotted cricket) [TaxID: 6999]
    Gryllus campestris [TaxID: 58607]
    Spodoptera frugiperda (Fall armyworm) [TaxID: 7108]
    ProteomesiUP000001359: Genome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 12731273DNA polymerase 037LPRO_0000376943Add
    BLAST

    Proteomic databases

    PRIDEiQ9QSK2.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9QSK2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili679 – 837159Sequence AnalysisAdd
    BLAST

    Sequence similaritiesi

    Belongs to the DNA polymerase type-B family.Curated

    Keywords - Domaini

    Coiled coil

    Family and domain databases

    Gene3Di3.30.420.10. 2 hits.
    3.90.1600.10. 2 hits.
    InterProiIPR006172. DNA-dir_DNA_pol_B.
    IPR006133. DNA-dir_DNA_pol_B_exonuc.
    IPR006134. DNA-dir_DNA_pol_B_multi_dom.
    IPR023211. DNA_pol_palm_dom.
    IPR012337. RNaseH-like_dom.
    [Graphical view]
    PfamiPF00136. DNA_pol_B. 1 hit.
    PF03104. DNA_pol_B_exo1. 1 hit.
    [Graphical view]
    SMARTiSM00486. POLBc. 1 hit.
    [Graphical view]
    SUPFAMiSSF53098. SSF53098. 3 hits.

    Sequencei

    Sequence statusi: Complete.

    Q9QSK2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEKTMFAYSW HQTDDETKNW SKSKESLRIY GITDDGKTIC LIVNDFKPFV     50
    HVELPSSINW RQKIGGQPKV QKIMDYLNFI LGDLKPVKNR TIFIDKYKLY 100
    GSNYVQTSPG VFQRKKFPYL VLFFESRKHI KNLEYKLKNT VDVPGFGKIK 150
    LNVRETNVSP ILQLCVERNL PSAGWIGFKV EGRGALAGYG ELVEEKKKFT 200
    DCDEEYVISK NYIYSIDKHV PVKAKVMAWD IEVYSEDGNF PDAMKPGNVV 250
    FQISCIFFIV GTSYKQKYLL TLGDPLEYTT TPINEEGCGK DTIVCKFKTE 300
    EDLIIAFSSL QKREKPHITT GWNIFNFDTT FLLKRAKLHR CLPNFLLQGF 350
    PKDQLGKEKE IKWQSKAYGT TDLKFIDCEG ILCIDLMDVV QKEHKLDSYS 400
    LNFVAKHFLG SKKDDLKPKE IFICYREGIK KEVKNIVIHP LSNNLNIYLG 450
    KEEIMIENKK FKKPLKPFFR IQNTGKLVSD EDDSVFHVNY RGEVFSFLIA 500
    VHNEEKYEIK TVSEFNNYKN AYGTYTLSAQ KAMAKVGKYC VQDSVLVADI 550
    FEHLQTWLSF SEMSRTCTTP IMTIHVHGQQ VKFFNQVYKY CYDHKTVTDK 600
    ETYKVDEKER YRGAEVFDPV PGLKRNVVPL DFASLYPSLI IARNMCYSTF 650
    VDNDDIPDEM CHVMEWDDHV ACSHDPKVIR KNAITEELEK LKKIANAKKM 700
    YTQGTRTYKK MMCSYLVMEN TKEKTEMSKH LKDLDRENNE LLNIVNKQTP 750
    GYIESIKKKI SDLTSERSEI TKKLSKSVMC VSNRRYRFLK EPKGILPTII 800
    QNLLDARKNT RTEIKNYKSR LALLMEKENK SKEDIDEITS IENLLPILDK 850
    RQNSYKISAN SMYGATGVRV GALPFMPIAM CTTYMGRKSI VEVSQYLKEL 900
    GGRVVYGDTD SNYVTFDDVV DKNVKVGTEE FSREMKKLWN HAIEIAKTIS 950
    KKFDNPITLE FENAIYFKFL ILTKKRYMYY TCGKDGNILM DANGKPKMGQ 1000
    RGVILSRRDN CKYMKDVYAN VIDKIFDEQS ENEILNGVVE KMLNLYTRQI 1050
    EFTSCEKDEN YLKNLIVTKS VGDYGGDKAT FEPILGKNEK GEDKWKIGNY 1100
    VVPLITDEII KTCGTNGLPM TQNEIKDWYL ERLPCQVQLE VKIKRRGHNK 1150
    EEGQRLSYVV TDIGCKGKQS EKIESVEYFK THSKVLKLDY GYYIERLIEP 1200
    LDQVFQAVFK NCQEKETIYS DNFRKTKLFS IFEKRGKHSQ ANFTKELHKL 1250
    CSVTKPKLIN EIKSFSKPDL VFV 1273
    Length:1,273
    Mass (Da):147,663
    Last modified:May 1, 2000 - v1
    Checksum:iCC514AD83F7299A3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF303741 Genomic DNA. Translation: AAD48150.1.
    AJ279816 Genomic DNA. Translation: CAC19195.1.
    RefSeqiNP_149500.1. NC_003038.1.

    Genome annotation databases

    GeneIDi921680.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF303741 Genomic DNA. Translation: AAD48150.1 .
    AJ279816 Genomic DNA. Translation: CAC19195.1 .
    RefSeqi NP_149500.1. NC_003038.1.

    3D structure databases

    ProteinModelPortali Q9QSK2.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q9QSK2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 921680.

    Family and domain databases

    Gene3Di 3.30.420.10. 2 hits.
    3.90.1600.10. 2 hits.
    InterProi IPR006172. DNA-dir_DNA_pol_B.
    IPR006133. DNA-dir_DNA_pol_B_exonuc.
    IPR006134. DNA-dir_DNA_pol_B_multi_dom.
    IPR023211. DNA_pol_palm_dom.
    IPR012337. RNaseH-like_dom.
    [Graphical view ]
    Pfami PF00136. DNA_pol_B. 1 hit.
    PF03104. DNA_pol_B_exo1. 1 hit.
    [Graphical view ]
    SMARTi SM00486. POLBc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53098. SSF53098. 3 hits.
    ProtoNeti Search...

    Publicationsi

    1. "Analysis of the first complete DNA sequence of an invertebrate iridovirus: coding strategy of the genome of Chilo iridescent virus."
      Jakob N.J., Mueller K., Bahr U., Darai G.
      Virology 286:182-196(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. "Phylogenetic position of the Diadromus pulchellus ascovirus DNA polymerase among viruses with large double-stranded DNA genomes."
      Stasiak K., Demattei M.V., Federici B.A., Bigot Y.
      J. Gen. Virol. 81:3059-3072(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 636-910.
    3. "Comparative genomic analysis of the family Iridoviridae: re-annotating and defining the core set of iridovirus genes."
      Eaton H.E., Metcalf J., Penny E., Tcherepanov V., Upton C., Brunetti C.R.
      Virol. J. 4:11-11(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENOME REANNOTATION.

    Entry informationi

    Entry nameiDPOL_IIV6
    AccessioniPrimary (citable) accession number: Q9QSK2
    Secondary accession number(s): Q9DIE2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 16, 2009
    Last sequence update: May 1, 2000
    Last modified: October 1, 2014
    This is version 72 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3