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Protein

DNA polymerase 037L

Gene

DPOL

Organism
Invertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

DNA-directed DNA polymerase involved in viral DNA replication.

Catalytic activityi

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. DNA-directed DNA polymerase activity Source: UniProtKB-KW
  3. nucleotide binding Source: InterPro

GO - Biological processi

  1. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase

Keywords - Biological processi

DNA replication

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA polymerase 037L (EC:2.7.7.7)
Gene namesi
Name:DPOL
ORF Names:IIV6-037L
OrganismiInvertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus)
Taxonomic identifieri176652 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageIridoviridaeIridovirus
Virus hostiAcheta domesticus (House cricket) [TaxID: 6997]
Chilo suppressalis (striped riceborer) [TaxID: 168631]
Gryllus bimaculatus (Two-spotted cricket) [TaxID: 6999]
Gryllus campestris [TaxID: 58607]
Spodoptera frugiperda (Fall armyworm) [TaxID: 7108]
ProteomesiUP000001359 Componenti: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 12731273DNA polymerase 037LPRO_0000376943Add
BLAST

Proteomic databases

PRIDEiQ9QSK2.

Structurei

3D structure databases

ProteinModelPortaliQ9QSK2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili679 – 837159Sequence AnalysisAdd
BLAST

Sequence similaritiesi

Belongs to the DNA polymerase type-B family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

KOiK18964.

Family and domain databases

Gene3Di3.30.420.10. 2 hits.
3.90.1600.10. 2 hits.
InterProiIPR006172. DNA-dir_DNA_pol_B.
IPR006133. DNA-dir_DNA_pol_B_exonuc.
IPR006134. DNA-dir_DNA_pol_B_multi_dom.
IPR023211. DNA_pol_palm_dom.
IPR012337. RNaseH-like_dom.
[Graphical view]
PfamiPF00136. DNA_pol_B. 1 hit.
PF03104. DNA_pol_B_exo1. 1 hit.
[Graphical view]
SMARTiSM00486. POLBc. 1 hit.
[Graphical view]
SUPFAMiSSF53098. SSF53098. 3 hits.

Sequencei

Sequence statusi: Complete.

Q9QSK2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKTMFAYSW HQTDDETKNW SKSKESLRIY GITDDGKTIC LIVNDFKPFV
60 70 80 90 100
HVELPSSINW RQKIGGQPKV QKIMDYLNFI LGDLKPVKNR TIFIDKYKLY
110 120 130 140 150
GSNYVQTSPG VFQRKKFPYL VLFFESRKHI KNLEYKLKNT VDVPGFGKIK
160 170 180 190 200
LNVRETNVSP ILQLCVERNL PSAGWIGFKV EGRGALAGYG ELVEEKKKFT
210 220 230 240 250
DCDEEYVISK NYIYSIDKHV PVKAKVMAWD IEVYSEDGNF PDAMKPGNVV
260 270 280 290 300
FQISCIFFIV GTSYKQKYLL TLGDPLEYTT TPINEEGCGK DTIVCKFKTE
310 320 330 340 350
EDLIIAFSSL QKREKPHITT GWNIFNFDTT FLLKRAKLHR CLPNFLLQGF
360 370 380 390 400
PKDQLGKEKE IKWQSKAYGT TDLKFIDCEG ILCIDLMDVV QKEHKLDSYS
410 420 430 440 450
LNFVAKHFLG SKKDDLKPKE IFICYREGIK KEVKNIVIHP LSNNLNIYLG
460 470 480 490 500
KEEIMIENKK FKKPLKPFFR IQNTGKLVSD EDDSVFHVNY RGEVFSFLIA
510 520 530 540 550
VHNEEKYEIK TVSEFNNYKN AYGTYTLSAQ KAMAKVGKYC VQDSVLVADI
560 570 580 590 600
FEHLQTWLSF SEMSRTCTTP IMTIHVHGQQ VKFFNQVYKY CYDHKTVTDK
610 620 630 640 650
ETYKVDEKER YRGAEVFDPV PGLKRNVVPL DFASLYPSLI IARNMCYSTF
660 670 680 690 700
VDNDDIPDEM CHVMEWDDHV ACSHDPKVIR KNAITEELEK LKKIANAKKM
710 720 730 740 750
YTQGTRTYKK MMCSYLVMEN TKEKTEMSKH LKDLDRENNE LLNIVNKQTP
760 770 780 790 800
GYIESIKKKI SDLTSERSEI TKKLSKSVMC VSNRRYRFLK EPKGILPTII
810 820 830 840 850
QNLLDARKNT RTEIKNYKSR LALLMEKENK SKEDIDEITS IENLLPILDK
860 870 880 890 900
RQNSYKISAN SMYGATGVRV GALPFMPIAM CTTYMGRKSI VEVSQYLKEL
910 920 930 940 950
GGRVVYGDTD SNYVTFDDVV DKNVKVGTEE FSREMKKLWN HAIEIAKTIS
960 970 980 990 1000
KKFDNPITLE FENAIYFKFL ILTKKRYMYY TCGKDGNILM DANGKPKMGQ
1010 1020 1030 1040 1050
RGVILSRRDN CKYMKDVYAN VIDKIFDEQS ENEILNGVVE KMLNLYTRQI
1060 1070 1080 1090 1100
EFTSCEKDEN YLKNLIVTKS VGDYGGDKAT FEPILGKNEK GEDKWKIGNY
1110 1120 1130 1140 1150
VVPLITDEII KTCGTNGLPM TQNEIKDWYL ERLPCQVQLE VKIKRRGHNK
1160 1170 1180 1190 1200
EEGQRLSYVV TDIGCKGKQS EKIESVEYFK THSKVLKLDY GYYIERLIEP
1210 1220 1230 1240 1250
LDQVFQAVFK NCQEKETIYS DNFRKTKLFS IFEKRGKHSQ ANFTKELHKL
1260 1270
CSVTKPKLIN EIKSFSKPDL VFV
Length:1,273
Mass (Da):147,663
Last modified:April 30, 2000 - v1
Checksum:iCC514AD83F7299A3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF303741 Genomic DNA. Translation: AAD48150.1.
AJ279816 Genomic DNA. Translation: CAC19195.1.
RefSeqiNP_149500.1. NC_003038.1.

Genome annotation databases

GeneIDi921680.
KEGGivg:921680.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF303741 Genomic DNA. Translation: AAD48150.1.
AJ279816 Genomic DNA. Translation: CAC19195.1.
RefSeqiNP_149500.1. NC_003038.1.

3D structure databases

ProteinModelPortaliQ9QSK2.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ9QSK2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi921680.
KEGGivg:921680.

Phylogenomic databases

KOiK18964.

Family and domain databases

Gene3Di3.30.420.10. 2 hits.
3.90.1600.10. 2 hits.
InterProiIPR006172. DNA-dir_DNA_pol_B.
IPR006133. DNA-dir_DNA_pol_B_exonuc.
IPR006134. DNA-dir_DNA_pol_B_multi_dom.
IPR023211. DNA_pol_palm_dom.
IPR012337. RNaseH-like_dom.
[Graphical view]
PfamiPF00136. DNA_pol_B. 1 hit.
PF03104. DNA_pol_B_exo1. 1 hit.
[Graphical view]
SMARTiSM00486. POLBc. 1 hit.
[Graphical view]
SUPFAMiSSF53098. SSF53098. 3 hits.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Analysis of the first complete DNA sequence of an invertebrate iridovirus: coding strategy of the genome of Chilo iridescent virus."
    Jakob N.J., Mueller K., Bahr U., Darai G.
    Virology 286:182-196(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "Phylogenetic position of the Diadromus pulchellus ascovirus DNA polymerase among viruses with large double-stranded DNA genomes."
    Stasiak K., Demattei M.V., Federici B.A., Bigot Y.
    J. Gen. Virol. 81:3059-3072(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 636-910.
  3. "Comparative genomic analysis of the family Iridoviridae: re-annotating and defining the core set of iridovirus genes."
    Eaton H.E., Metcalf J., Penny E., Tcherepanov V., Upton C., Brunetti C.R.
    Virol. J. 4:11-11(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.

Entry informationi

Entry nameiDPOL_IIV6
AccessioniPrimary (citable) accession number: Q9QSK2
Secondary accession number(s): Q9DIE2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 15, 2009
Last sequence update: April 30, 2000
Last modified: March 31, 2015
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.