Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Genome polyprotein

Gene

ns3

Organism
Hepatitis C virus
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHelicaseSAAS annotation, Hydrolase, Nucleotidyltransferase, RNA-directed RNA polymeraseSAAS annotation, Transferase
Biological processViral RNA replicationSAAS annotation
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Genome polyproteinSAAS annotation
Gene namesi
Name:ns3Imported
OrganismiHepatitis C virusImported
Taxonomic identifieri11103 [NCBI]
Taxonomic lineageiVirusesssRNA virusesssRNA positive-strand viruses, no DNA stageFlaviviridaeHepacivirus

Subcellular locationi

  • Virion SAAS annotation

GO - Cellular componenti

  • virion Source: UniProtKB-SubCell

Keywords - Cellular componenti

VirionSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliQ9QP07.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini175 – 327Helicase ATP-bindingInterPro annotationAdd BLAST153
Domaini319 – 496Helicase C-terminalInterPro annotationAdd BLAST178

Family and domain databases

InterProiView protein in InterPro
IPR011492. DEAD_Flavivir.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR009003. Peptidase_S1_PA.
IPR004109. Peptidase_S29.
PfamiView protein in Pfam
PF07652. Flavi_DEAD. 1 hit.
PF02907. Peptidase_S29. 1 hit.
SMARTiView protein in SMART
SM00487. DEXDc. 1 hit.
SUPFAMiSSF50494. SSF50494. 1 hit.
SSF52540. SSF52540. 2 hits.
PROSITEiView protein in PROSITE
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q9QP07-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
IITSLTGRDK NQVEGEVQVV STATQSFLAT CINGVCWTVF HGAGTKTLAG
60 70 80 90 100
PKGPITQMYT NVDQDLVGWQ APPGARSMTP CTCGSSDPYL VTRHADVIPV
110 120 130 140 150
RRRGDCRGSL LSPRPISYLK GSSGGPLLCP SGHAVGNFRA AVCTRGVAKA
160 170 180 190 200
VDFIPVESME TTMRSPVFTD NSSPPAVPQT FQVAHLHAPT GSGKSTKVPA
210 220 230 240 250
AYATQGYKVL VLNPSVAATL GFGAYMSKAY GTDPNIRTGV RTITTGAPIT
260 270 280 290 300
YSTYGKFLAD GGCSGGAYDI IICDECHSTD STTILGIGTV LDQAETAGAR
310 320 330 340 350
LVVLATATPP GSVTVPHPNI EEVALSNTGE IPFYGKAIPI EAIKGGRHLI
360 370 380 390 400
FCHSKKKCDE LAAKLSALGL NAVAYYRGLD VSVIPTSGDV VAVATDALMT
410 420 430 440 450
GFTGDFDSVI DCNTCVAQTV DFSLDPTFTI ETTTVPQDAV SRSQRRGRTG
460 470 480 490 500
RGRRGIYRFV TPGERPLGMF DSSVLCECYD AGCAWYELTP AETSVRLRAY
510 520 530 540 550
LNTPGLPVCQ DHLEFWESVF TGLTHIDAHF LSQTKQAGDN FPYLVAYQAT
560 570 580 590
VCARAQAPPP SWDQMWKCLT RLKPTLHGPT PLLYRLGAVQ NEV
Length:593
Mass (Da):63,136
Last modified:May 1, 2000 - v1
Checksum:iE2A5860CF1C894BA
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei593Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ238652 mRNA. Translation: CAB51915.1.
PIRiPS0329.

Similar proteinsi

Entry informationi

Entry nameiQ9QP07_9HEPC
AccessioniPrimary (citable) accession number: Q9QP07
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: April 12, 2017
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)