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Q9QBU1 (P14_POLVP) Reviewed, UniProtKB/Swiss-Prot

Last modified February 6, 2013. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
RNA silencing suppressor p14
Gene names
ORF Names:ORF4
OrganismPothos latent virus (isolate Pigeonpea/India) (PoLV) [Reference proteome]
Taxonomic identifier652109 [NCBI]
Taxonomic lineageVirusesssRNA positive-strand viruses, no DNA stageTombusviridaeAureusvirus
Virus hostCajanus cajan (Pigeon pea) (Cajanus indicus) [TaxID: 3821]
Pothos [TaxID: 174212]

Protein attributes

Sequence length130 AA.
Sequence statusComplete.
Protein existencePredicted

General annotation (Comments)

Function

Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs. Binds to dsRNAs without size specificity. Ref.2

Ontologies

Keywords
   LigandRNA-binding
   Molecular functionSuppressor of RNA silencing
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular_functionRNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 130130RNA silencing suppressor p14
PRO_0000399483

Sequences

Sequence LengthMass (Da)Tools
Q9QBU1 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: FF6079F7C895D91F

FASTA13014,183
        10         20         30         40         50         60 
MENSQTGVLC PNRCQVCSHT TYIRESSGQG GRQACRFTRF VTQPRVVSEQ GIQYRSWLSD 

        70         80         90        100        110        120 
RGFPATLLST SGGLSTTIRG HGVAVTIQGD SKSLLNFCRV AYDVFHHPVV QSEVCHGSGP 

       130 
ATSDEITTKF 

« Hide

References

[1]"Characterization of a virus from pigeonpea with affinities to species in the genus Aureusvirus, family Tombusviridae."
Lava Kumar P., Jones A.T., Sreenivasulu P., Fenton B., Reddy D.V.R.
Plant Dis. 85:208-215(2001) [AGRICOLA] [Europe PMC]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
[2]"Aureusvirus P14 is an efficient RNA silencing suppressor that binds double-stranded RNAs without size specificity."
Merai Z., Kerenyi Z., Molnar A., Barta E., Valoczi A., Bisztray G., Havelda Z., Burgyan J., Silhavy D.
J. Virol. 79:7217-7226(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ243370 Genomic RNA. Translation: CAB59796.1.
RefSeqNP_051034.1. NC_000939.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1403810.

Family and domain databases

ProtoNetSearch...

Entry information

Entry nameP14_POLVP
AccessionPrimary (citable) accession number: Q9QBU1
Entry history
Integrated into UniProtKB/Swiss-Prot: October 5, 2010
Last sequence update: May 1, 2000
Last modified: February 6, 2013
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program