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Protein

RNA silencing suppressor p14

Gene

ORF4

Organism
Pothos latent virus (isolate Pigeonpea/India) (PoLV)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs. Binds to dsRNAs without size specificity.1 Publication

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Suppressor of RNA silencing

Keywords - Ligandi

RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
RNA silencing suppressor p14
Gene namesi
ORF Names:ORF4
OrganismiPothos latent virus (isolate Pigeonpea/India) (PoLV)
Taxonomic identifieri652109 [NCBI]
Taxonomic lineageiVirusesssRNA virusesssRNA positive-strand viruses, no DNA stageTombusviridaeAureusvirus
Virus hostiCajanus cajan (Pigeon pea) (Cajanus indicus) [TaxID: 3821]
Pothos [TaxID: 174212]
ProteomesiUP000000572 Componenti: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 130130RNA silencing suppressor p14PRO_0000399483Add
BLAST

Sequencei

Sequence statusi: Complete.

Q9QBU1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENSQTGVLC PNRCQVCSHT TYIRESSGQG GRQACRFTRF VTQPRVVSEQ
60 70 80 90 100
GIQYRSWLSD RGFPATLLST SGGLSTTIRG HGVAVTIQGD SKSLLNFCRV
110 120 130
AYDVFHHPVV QSEVCHGSGP ATSDEITTKF
Length:130
Mass (Da):14,183
Last modified:May 1, 2000 - v1
Checksum:iFF6079F7C895D91F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ243370 Genomic RNA. Translation: CAB59796.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ243370 Genomic RNA. Translation: CAB59796.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

ProtoNetiSearch...

Publicationsi

  1. "Characterization of a virus from pigeonpea with affinities to species in the genus Aureusvirus, family Tombusviridae."
    Lava Kumar P., Jones A.T., Sreenivasulu P., Fenton B., Reddy D.V.R.
    Plant Dis. 85:208-215(2001)
    [AGRICOLA] [Europe PMC]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
  2. "Aureusvirus P14 is an efficient RNA silencing suppressor that binds double-stranded RNAs without size specificity."
    Merai Z., Kerenyi Z., Molnar A., Barta E., Valoczi A., Bisztray G., Havelda Z., Burgyan J., Silhavy D.
    J. Virol. 79:7217-7226(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.

Entry informationi

Entry nameiP14_POLVP
AccessioniPrimary (citable) accession number: Q9QBU1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 5, 2010
Last sequence update: May 1, 2000
Last modified: June 24, 2015
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.