SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9QAZ8

- RDRP_SJNNV

UniProt

Q9QAZ8 - RDRP_SJNNV

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
RNA-directed RNA polymerase
Gene
N/A
Organism
Striped jack nervous necrosis virus (SjNNV)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

RNA-dependent RNA polymerase which replicates the viral genome composed of 2 RNA segments, RNA1 AND RNA2 Reviewed prediction.

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).

GO - Molecular functioni

  1. RNA binding Source: InterPro
  2. RNA-directed RNA polymerase activity Source: UniProtKB-KW
  3. nucleotide binding Source: UniProtKB-KW

GO - Biological processi

  1. transcription, DNA-templated Source: InterPro
  2. viral RNA genome replication Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, RNA-directed RNA polymerase, Transferase

Keywords - Biological processi

Viral RNA replication

Keywords - Ligandi

Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
RNA-directed RNA polymerase (EC:2.7.7.48)
Short name:
RdRp
Alternative name(s):
RNA replicase
Short name:
Protein A
OrganismiStriped jack nervous necrosis virus (SjNNV)
Taxonomic identifieri35297 [NCBI]
Taxonomic lineageiVirusesssRNA positive-strand viruses, no DNA stageNodaviridaeBetanodavirus
Virus hostiDicentrarchus labrax (European seabass) (Morone labrax) [TaxID: 13489]
Epinephelus akaara (Hong Kong grouper) (Serranus akaara) [TaxID: 215347]
Hippoglossus hippoglossus (Atlantic halibut) (Pleuronectes hippoglossus) [TaxID: 8267]
Lates calcarifer (Barramundi) (Holocentrus calcarifer) [TaxID: 8187]
Oplegnathus fasciatus (Barred knifejaw) (Scaradon fasciatus) [TaxID: 163134]
ProteomesiUP000000414: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 983983RNA-directed RNA polymerase
PRO_0000222450Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ9QAZ8.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini579 – 701123RdRp catalytic
Add
BLAST

Sequence similaritiesi

Family and domain databases

InterProiIPR007094. RNA-dir_pol_PSvirus.
IPR001788. Tymovirus_RNA-dep_RNA_pol.
[Graphical view]
PfamiPF00978. RdRP_2. 1 hit.
[Graphical view]
PROSITEiPS50507. RDRP_SSRNA_POS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9QAZ8-1 [UniParc]FASTAAdd to Basket

« Hide

MRRFEFELAR MSGAAFCVVT GYRLLTSKWL ADRVEDYRQR VIADRKQILR    50
DAAVIRTSIQ KQMELVRISV RKGHSHQEAA TERNSATDTM IGVVEKCGYE 100
PYIISPSPRE KEYHGSRQFY SLADFRQDYR RDEITDRHVI VMTDVDYYVD 150
MHELVGLGVP ILLYTFQPST VSGEVKDGYF TITDDHVHYR VAGGKDVRHR 200
IWNYNQDTMF VRSKPRGFWA SLKQILRDIT GITALCGYLY LKLGIAPFGD 250
QVTLFTVDQF KMGEHRNIVS IVPFATCRSN LLKISEYGAE LDYMRYQQRN 300
NNANFNAVTY ISQEGPLISL GLEGNFASVQ LPLQDFENIR TAYELSKNNN 350
LSDTVRRSAR SCKEAAIIHK CLQAGCDLAS EVVHKPGELA RHYQALGDTY 400
DIDPSEQGKC YAREYAPGPL TQTAVFPSES RSNELATIDG RIAGPQAKAK 450
SREHITPKMH KVARDFVRHL VPTAGLGRPY PLTYVEEHQT KPLQRARNDA 500
NRYHDEFTMI VKAFQKKEAY NAPNYPRNIS TVPHTQNVKL SSYTYAFKEA 550
VLQHVPWYMP THTPAEIAEA VQSLAASSTE LVETDYSKFD GTFLRFMREN 600
VEFAIYKRWV HLDHLTELST LLGNELQAPA VTRLGIKYDP DCSRLSGSAL 650
TTDGNSIANA FVSYLAGRQA GMDDDEAWTW IGIVYGDDGL RSGNVSDALL 700
SKTASSLGFD LKIVNRAPRG SPVTFLSRVY LDPWSSPASV QSPLRTLLKL 750
HTTCDTQSDI EDVGWAKTQA YLVTDCLTPF IGHWCRAYQR NCTARVVQYA 800
DYNDIPFWVK NEDHVGNSWP QSDSVDWNDV VANELGLTTA ELLKHLAALD 850
AYTGPVSGLP RLTTSLDLEP KMPVALDGEV QAGPSQQPQT DKDGTSPTGD 900
RSAPRRARTA LQDADGRACR SRRSDRSPGK RDANVRDKRQ RRSTTPPRSR 950
PSVPGPSSSG RRTDGDRVRG GAARQRQRRR SPV 983
Length:983
Mass (Da):110,630
Last modified:May 1, 2000 - v1
Checksum:iF76890AA597F8BE1
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB025018 Genomic RNA. Translation: BAA84210.1.
AB056571 Genomic RNA. Translation: BAB64329.1.
RefSeqiNP_599247.1. NC_003448.1.

Genome annotation databases

GeneIDi991144.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB025018 Genomic RNA. Translation: BAA84210.1 .
AB056571 Genomic RNA. Translation: BAB64329.1 .
RefSeqi NP_599247.1. NC_003448.1.

3D structure databases

ProteinModelPortali Q9QAZ8.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 991144.

Family and domain databases

InterProi IPR007094. RNA-dir_pol_PSvirus.
IPR001788. Tymovirus_RNA-dep_RNA_pol.
[Graphical view ]
Pfami PF00978. RdRP_2. 1 hit.
[Graphical view ]
PROSITEi PS50507. RDRP_SSRNA_POS. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Sequence of the non-structural protein gene encoded by RNA1 of striped jack nervous necrosis virus."
    Nagai T., Nishizawa T.
    J. Gen. Virol. 80:3019-3022(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
  2. "Establishment of an infectious RNA transcription system for striped jack nervous necrosis virus, the type species of the betanodaviruses."
    Iwamoto T., Mise K., Mori K., Arimoto M., Nakai T., Okuno T.
    J. Gen. Virol. 82:2653-2662(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Entry informationi

Entry nameiRDRP_SJNNV
AccessioniPrimary (citable) accession number: Q9QAZ8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 16, 2002
Last sequence update: May 1, 2000
Last modified: April 16, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi