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Q9Q944 (PAP1_RFVKA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Poly(A) polymerase catalytic subunit

EC=2.7.7.19
Alternative name(s):
Poly(A) polymerase large subunit
Short name=PAP-L
Gene names
Name:PAPL
Ordered Locus Names:s027L
OrganismRabbit fibroma virus (strain Kasza) (RFV) (Shope fibroma virus (strain Kasza)) [Reference proteome]
Taxonomic identifier10272 [NCBI]
Taxonomic lineageVirusesdsDNA viruses, no RNA stagePoxviridaeChordopoxvirinaeLeporipoxvirus
Virus hostOryctolagus cuniculus (Rabbit) [TaxID: 9986]

Protein attributes

Sequence length470 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Polymerase that creates the 3'-poly(A) tail of mRNA's.

Catalytic activity

ATP + RNA(n) = diphosphate + RNA(n+1).

Subunit structure

Heterodimer of a large (catalytic) subunit and a small (regulatory) subunit By similarity.

Sequence similarities

Belongs to the poxviridae poly(A) polymerase catalytic subunit family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 470470Poly(A) polymerase catalytic subunit
PRO_0000308939

Sites

Active site1921 By similarity
Active site1941 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9Q944 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 52E6BC4F2F215A9E

FASTA47053,841
        10         20         30         40         50         60 
MNARIADLLY NYLGRPPSLS EYHMLKLQHR NIQKIIAFNK DIFISLIKKN KKKFFSDIDL 

        70         80         90        100        110        120 
TSSEIKTSVL SYFSKQRDTY SIGKLYTIIE LQTILVSTYT DVLGVLTLKG PDMFPSSTRY 

       130        140        150        160        170        180 
DIKSIKQIAT SALHAMNVAV ISDKVMGRHN VSPLVSNVNA LMEEYLRRHN KNCICYGSYS 

       190        200        210        220        230        240 
LYLLNPEVKY GDIDILQTNS RTFLIDLAFL IKFITGSNVV LLKVPYLKNY MVLKDKDDNH 

       250        260        270        280        290        300 
IIDSFNIRQE TMQVIPKVLI DNIYIVDPAL QLMSMFKMFS QIDRLEDLAR NPEKLTVRLA 

       310        320        330        340        350        360 
TLMEYVRVKY GIILNGESNH MPMKGVLDKD KRIIDVDTSG YNFSFKKCYV YLDESSLSSD 

       370        380        390        400        410        420 
ILDLNADDAV DFENVSNSAY LINGDVLYTY FSNTILLSDP DTIHEISNKA MSAHILIYQI 

       430        440        450        460        470 
LTGNDIRQPL SDLVNSLMYN EKVLIHEVIP RDKKTGKHGI VDIEKDIITH 

« Hide

References

[1]"The complete genome sequence of shope (Rabbit) fibroma virus."
Willer D.O., McFadden G., Evans D.H.
Virology 264:319-343(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF170722 Genomic DNA. Translation: AAF17910.1.
RefSeqNP_051916.1. NC_001266.1.

3D structure databases

ProteinModelPortalQ9Q944.
SMRQ9Q944. Positions 8-468.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1486871.

Family and domain databases

InterProIPR024231. Pox_polyA_pol_nucTrfase.
IPR004976. Poxvirus_polyA_pol_cat.
IPR024397. Poxvirus_polyA_pol_cat_C.
IPR024398. Poxvirus_polyA_pol_cat_N.
[Graphical view]
PfamPF03296. Pox_polyA_pol. 1 hit.
PF12629. Pox_polyA_pol_C. 1 hit.
PF12630. Pox_polyA_pol_N. 1 hit.
[Graphical view]
PIRSFPIRSF015693. VAC-48L_nuct. 1 hit.
ProtoNetSearch...

Entry information

Entry namePAP1_RFVKA
AccessionPrimary (citable) accession number: Q9Q944
Entry history
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: May 1, 2000
Last modified: May 14, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families