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Protein

Poly(A) polymerase catalytic subunit

Gene

PAPL

Organism
Myxoma virus (strain Lausanne) (MYXV)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Polymerase that creates the 3'-poly(A) tail of mRNA's.

Catalytic activityi

ATP + RNA(n) = diphosphate + RNA(n+1).

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei192By similarity1
Active sitei194By similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase
Biological processmRNA processing, Transcription
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Poly(A) polymerase catalytic subunit (EC:2.7.7.19)
Alternative name(s):
Poly(A) polymerase large subunit
Short name:
PAP-L
Gene namesi
Name:PAPL
Ordered Locus Names:m027L
OrganismiMyxoma virus (strain Lausanne) (MYXV)
Taxonomic identifieri31530 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stagePoxviridaeChordopoxvirinaeLeporipoxvirus
Virus hostiOryctolagus cuniculus (Rabbit) [TaxID: 9986]
Proteomesi
  • UP000000867 Componenti: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003089361 – 470Poly(A) polymerase catalytic subunitAdd BLAST470

Proteomic databases

PRIDEiQ9Q8R9

Interactioni

Subunit structurei

Heterodimer of a large (catalytic) subunit and a small (regulatory) subunit.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ9Q8R9
SMRiQ9Q8R9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK21315
OrthoDBiVOG0900007K

Family and domain databases

Gene3Di1.20.1270.320, 1 hit
3.30.460.60, 1 hit
InterProiView protein in InterPro
IPR037265 PolyA_pol_cat_sf
IPR024231 Pox_polyA_pol_nucTrfase
IPR038419 Pox_polyA_pol_nucTrfase_sf
IPR004976 Poxviridae_polyA_pol_cat
IPR024397 Poxvirus_polyA_pol_cat_C
IPR024398 Poxvirus_polyA_pol_cat_N
IPR038337 Poxvirus_polyA_pol_cat_N_sf
PfamiView protein in Pfam
PF03296 Pox_polyA_pol, 1 hit
PF12629 Pox_polyA_pol_C, 1 hit
PF12630 Pox_polyA_pol_N, 1 hit
PIRSFiPIRSF015693 VAC-48L_nuct, 1 hit
SUPFAMiSSF160957 SSF160957, 1 hit

Sequencei

Sequence statusi: Complete.

Q9Q8R9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNARIAELLH NYLGRPPSLS EYHMLKLQHR NIQKIIAFNK DIFISLIKKN
60 70 80 90 100
KKKFFSDIDL TSSEIKTSVL SYFSKQRDTY SIGKLYTIIE LQTILVSTYT
110 120 130 140 150
DVLGVLTLKG PDMFPSSTRY DIKSIKQIAT SALHAMNVAV LSDKVMGRHN
160 170 180 190 200
VSPLVSNVNA LMEEYLRRHN KNCICYGSYS LHLLNPEVKY GDIDILQTNS
210 220 230 240 250
RTFLIDLAFL IKFITGSNVI LLKVPYLKNY MVLKDKDDNH IIDSFNIRQE
260 270 280 290 300
TMQVIPKVLI DNIYIVDPAL QLMSMFKMFS QIDRLEDLAR NPEKLTVRLA
310 320 330 340 350
TLMEYVRVKY GVILNGESNH MPMKGVLDKD KRIIVMDTSG YNFSFKKCFV
360 370 380 390 400
YMDESSLSSD ILDLNADDAV DFENVSNSAY LVKGDVLYTY FSNTILLSDP
410 420 430 440 450
DTIHEISNKA MSAHILIYQI LTGNDIRQPL SDLVNSLMYN EKVLIHEVIP
460 470
RDKKTGKHGI IDIEKDIITH
Length:470
Mass (Da):53,836
Last modified:May 1, 2000 - v1
Checksum:i65A8F42653A85D0F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF170726 Genomic DNA Translation: AAF14915.1
RefSeqiNP_051741.1, NC_001132.2

Genome annotation databases

GeneIDi932202
KEGGivg:932202

Similar proteinsi

Entry informationi

Entry nameiPAP1_MYXVL
AccessioniPrimary (citable) accession number: Q9Q8R9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: May 1, 2000
Last modified: May 23, 2018
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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