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Q9Q8R9 (PAP1_MYXVL) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Poly(A) polymerase catalytic subunit

EC=2.7.7.19
Alternative name(s):
Poly(A) polymerase large subunit
Short name=PAP-L
Gene names
Name:PAPL
Ordered Locus Names:m027L
OrganismMyxoma virus (strain Lausanne) (MYXV) [Reference proteome]
Taxonomic identifier31530 [NCBI]
Taxonomic lineageVirusesdsDNA viruses, no RNA stagePoxviridaeChordopoxvirinaeLeporipoxvirus
Virus hostOryctolagus cuniculus (Rabbit) [TaxID: 9986]

Protein attributes

Sequence length470 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Polymerase that creates the 3'-poly(A) tail of mRNA's.

Catalytic activity

ATP + RNA(n) = diphosphate + RNA(n+1).

Subunit structure

Heterodimer of a large (catalytic) subunit and a small (regulatory) subunit By similarity.

Sequence similarities

Belongs to the poxviridae poly(A) polymerase catalytic subunit family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 470470Poly(A) polymerase catalytic subunit
PRO_0000308936

Sites

Active site1921 By similarity
Active site1941 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9Q8R9 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 65A8F42653A85D0F

FASTA47053,836
        10         20         30         40         50         60 
MNARIAELLH NYLGRPPSLS EYHMLKLQHR NIQKIIAFNK DIFISLIKKN KKKFFSDIDL 

        70         80         90        100        110        120 
TSSEIKTSVL SYFSKQRDTY SIGKLYTIIE LQTILVSTYT DVLGVLTLKG PDMFPSSTRY 

       130        140        150        160        170        180 
DIKSIKQIAT SALHAMNVAV LSDKVMGRHN VSPLVSNVNA LMEEYLRRHN KNCICYGSYS 

       190        200        210        220        230        240 
LHLLNPEVKY GDIDILQTNS RTFLIDLAFL IKFITGSNVI LLKVPYLKNY MVLKDKDDNH 

       250        260        270        280        290        300 
IIDSFNIRQE TMQVIPKVLI DNIYIVDPAL QLMSMFKMFS QIDRLEDLAR NPEKLTVRLA 

       310        320        330        340        350        360 
TLMEYVRVKY GVILNGESNH MPMKGVLDKD KRIIVMDTSG YNFSFKKCFV YMDESSLSSD 

       370        380        390        400        410        420 
ILDLNADDAV DFENVSNSAY LVKGDVLYTY FSNTILLSDP DTIHEISNKA MSAHILIYQI 

       430        440        450        460        470 
LTGNDIRQPL SDLVNSLMYN EKVLIHEVIP RDKKTGKHGI IDIEKDIITH 

« Hide

References

[1]"The complete DNA sequence of myxoma virus."
Cameron C., Hota-Mitchell S., Chen L., Barrett J.W., Cao J.-X., Macaulay C., Willer D.O., Evans D.H., McFadden G.
Virology 264:298-318(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF170726 Genomic DNA. Translation: AAF14915.1.
RefSeqNP_051741.1. NC_001132.2.

3D structure databases

ProteinModelPortalQ9Q8R9.
SMRQ9Q8R9. Positions 7-468.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID932202.

Family and domain databases

InterProIPR024231. Pox_polyA_pol_nucTrfase.
IPR004976. Poxvirus_polyA_pol_cat.
IPR024397. Poxvirus_polyA_pol_cat_C.
IPR024398. Poxvirus_polyA_pol_cat_N.
[Graphical view]
PfamPF03296. Pox_polyA_pol. 1 hit.
PF12629. Pox_polyA_pol_C. 1 hit.
PF12630. Pox_polyA_pol_N. 1 hit.
[Graphical view]
PIRSFPIRSF015693. VAC-48L_nuct. 1 hit.
ProtoNetSearch...

Entry information

Entry namePAP1_MYXVL
AccessionPrimary (citable) accession number: Q9Q8R9
Entry history
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: May 1, 2000
Last modified: May 14, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families