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Protein
Submitted name:

V-1 protease

Gene

ORF

Organism
Human immunodeficiency virus 1
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, ProteaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
V-1 proteaseImported
Gene namesi
Name:ORFImported
OrganismiHuman immunodeficiency virus 1Imported
Taxonomic identifieri11676 [NCBI]
Taxonomic lineageiVirusesRetro-transcribing virusesRetroviridaeOrthoretrovirinaeLentivirusPrimate lentivirus group
Virus hostiHomo sapiens (Human) [TaxID: 9606]

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
ANKZF1Q9H8Y52EBI-6248094,EBI-724848From a different organism.
ARRB2P321213EBI-6248094,EBI-714559From a different organism.
CCAR2Q8N1635EBI-6248094,EBI-355410From a different organism.
DIAPH1O606102EBI-6248094,EBI-3959709From a different organism.
DOK1Q997042EBI-6248094,EBI-1384360From a different organism.
EIF3AQ141525EBI-6248094,EBI-366617From a different organism.
EIF3CQ996135EBI-6248094,EBI-353741From a different organism.
EIF3DO153715EBI-6248094,EBI-353818From a different organism.
EIF3EP602285EBI-6248094,EBI-347740From a different organism.
EIF3FO003033EBI-6248094,EBI-711990From a different organism.
EIF3HO153723EBI-6248094,EBI-709735From a different organism.
EIF3KQ9UBQ55EBI-6248094,EBI-354344From a different organism.
EIF3LQ9Y2625EBI-6248094,EBI-373519From a different organism.
EIF3MQ7L2H72EBI-6248094,EBI-353901From a different organism.
FNIP1Q8TF403EBI-6248094,EBI-2946919From a different organism.
FOXC1Q129483EBI-6248094,EBI-1175253From a different organism.
IFT122Q9HBG63EBI-6248094,EBI-2805994From a different organism.
LIMD1Q9UGP45EBI-6248094,EBI-2652871From a different organism.
MCM4P339913EBI-6248094,EBI-374938From a different organism.
NFU1Q9UMS03EBI-6248094,EBI-725252From a different organism.
OSBPL3Q9H4L55EBI-6248094,EBI-1051317From a different organism.
OSBPL6Q9BZF33EBI-6248094,EBI-2372709From a different organism.
PARP4Q9UKK33EBI-6248094,EBI-2623021From a different organism.
POLE3Q9NRF95EBI-6248094,EBI-744901From a different organism.
POLE4Q9NR332EBI-6248094,EBI-867034From a different organism.
PUM2Q8TB723EBI-6248094,EBI-311190From a different organism.
SF3A3Q128743EBI-6248094,EBI-1051880From a different organism.
SSSCA1O602324EBI-6248094,EBI-741415From a different organism.
TRPS1Q9UHF73EBI-6248094,EBI-2556151From a different organism.
VBP1P617583EBI-6248094,EBI-357430From a different organism.

Protein-protein interaction databases

IntActiQ9Q2G4. 55 interactions.

Structurei

3D structure databases

ProteinModelPortaliQ9Q2G4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini20 – 8970Peptidase A2InterPro annotationAdd
BLAST

Sequence similaritiesi

Contains peptidase A2 domain.SAAS annotation

Family and domain databases

Gene3Di2.40.70.10. 1 hit.
InterProiIPR001969. Aspartic_peptidase_AS.
IPR001995. Peptidase_A2_cat.
IPR021109. Peptidase_aspartic_dom.
IPR018061. Retropepsins.
[Graphical view]
PfamiPF00077. RVP. 1 hit.
[Graphical view]
SUPFAMiSSF50630. SSF50630. 1 hit.
PROSITEiPS50175. ASP_PROT_RETROV. 1 hit.
PS00141. ASP_PROTEASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q9Q2G4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
PQITLWQRPL VTIKIGGQLK EALLDTGADD TVLEEMNLPG RWKPKMIGGI
60 70 80 90
GGFIKVRQYD QILIEICGHK AIGTVLVGPT PVNIIGRNLL TQIGCTLNF
Length:99
Mass (Da):10,820
Last modified:May 1, 2000 - v1
Checksum:i189F5EE42D82533D
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei99 – 991Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ279608 mRNA. Translation: CAB66021.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ279608 mRNA. Translation: CAB66021.1.

3D structure databases

ProteinModelPortaliQ9Q2G4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9Q2G4. 55 interactions.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di2.40.70.10. 1 hit.
InterProiIPR001969. Aspartic_peptidase_AS.
IPR001995. Peptidase_A2_cat.
IPR021109. Peptidase_aspartic_dom.
IPR018061. Retropepsins.
[Graphical view]
PfamiPF00077. RVP. 1 hit.
[Graphical view]
SUPFAMiSSF50630. SSF50630. 1 hit.
PROSITEiPS50175. ASP_PROT_RETROV. 1 hit.
PS00141. ASP_PROTEASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9Q2G4_9HIV1
AccessioniPrimary (citable) accession number: Q9Q2G4
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: September 7, 2016
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.