Q9PZM6 (Q9PZM6_9INFA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Neuraminidase EMBL AAF02314.1
Organism	Influenza A virus (A/Aquatic bird/Hong Kong/M603/98(H11N1)) EMBL AAF02314.1
Taxonomic identifier	129775 [NCBI]
Taxonomic lineage	Viruses › ssRNA negative-strand viruses › Orthomyxoviridae › Influenzavirus A

Protein attributes

Sequence length	454 AA.
Sequence status	Fragment.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic linkages of terminal sialic acid residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates. SAAS SAAS011040
Subunit structure	Homotetramer By similarity. SAAS SAAS011040

Ontologies

Keywords
Cellular component	Host cell membrane SAAS SAAS011040 Host membrane Membrane Virion SAAS SAAS011040
Domain	Transmembrane Transmembrane helix SAAS SAAS011040
Molecular function	Glycosidase SAAS SAAS011040 Hydrolase
PTM	Disulfide bond SAAS SAAS011040
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	host cell plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW virion Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	exo-alpha-sialidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAF02314.1

Sequences

	Sequence		Length	Mass (Da)
	Q9PZM6 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: FEC0FB03F35849AC	FASTA	454	49,847
	10 20 30 40 50 60 VIGIVSLMLQ IGNIISIWVS HSIQTGNQHQ PEPCNQSIIT YENNTWVNQT YVNISNTNFL 70 80 90 100 110 120 TEQAVTSVTL AGNSSLCPIS GWAIHSKDNG IRIGSKGDVF VIREPFISCS HLECRTFFLT 130 140 150 160 170 180 QGALLNDKHS NGTVKDRSPY RTLMSCPVGE APSPYNSRFE SVAWSASACH DGISWLTIGI 190 200 210 220 230 240 SGPDNGAVAV LKYNGIITDT IKSWRNNILR TQESECACVN GSCFTVMTDG PSNGQASYKI 250 260 270 280 290 300 FKIEKGKVVK SVELNAPNYH YEECSCYPDA GEITCVCRDN WHGSNRPWVS FNQNLEYQIG 310 320 330 340 350 360 YICSGVFGDN PRPNDGTGSC GPVSSNGAYG VKGFSFKYGN GVWIGRTKST SSRSGFEMIW 370 380 390 400 410 420 DPNGWTETDS SFSMKQDIVA ITDWSGYSGS FVQHPELTGL NCMRPCFWVE LIRGRPKENT 430 440 450 IWTSGSSISF CGVNSDTVGW SWPDGAELPF TIDK

References

[1]	"Rapid evolution of H5N1 influenza viruses in chickens in Hong Kong." Zhou N.N., Shortridge K.F., Claas E.C.J., Krauss S.L., Webster R.G. J. Virol. 73:3366-3374(1999) [PubMed: 10074191] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: A/Aquatic Bird/Hong Kong/m603/98 EMBL AAF02314.1.
[2]	"Evolution of H5N1 avian influenza viruses in Asia." World Health Organization Global Influenza Program Surveillance Network Emerg. Infect. Dis. 11:1515-1521(2005) [PubMed: 16318689] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: A/Aquatic Bird/Hong Kong/m603/98 EMBL AAF02314.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF098551 Viral cRNA. Translation: AAF02314.1.
3D structure databases
HSSP	HSSP built from PDB template 1F8E based on UniProtKB P03472.
ProteinModelPortal	Q9PZM6.
ModBase	Search...
Protein family/group databases
CAZy	GH34. Glycoside Hydrolase Family 34.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR001860. Glyco_hydro_34. IPR011040. Neuraminidase. [Graphical view]
Gene3D	G3DSA:2.120.10.10. Neuraminidase. 1 hit.
Pfam	PF00064. Neur. 1 hit. [Graphical view]
SUPFAM	SSF50939. Sialidase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q9PZM6_9INFA

Accession

Primary (citable) accession number: Q9PZM6

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	January 25, 2012
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)