Unreviewed, UniProtKB/TrEMBL Q9PZM6 (Q9PZM6_9INFA)

Names and origin

Protein names	Submitted name:     Neuraminidase EMBL AAF02314.1
Organism	Influenza A virus (A/Aquatic bird/Hong Kong/M603/98(H11N1)) EMBL AAF02314.1
Taxonomic identifier	129775 [NCBI]
Taxonomic lineage	Viruses › ssRNA negative-strand viruses › Orthomyxoviridae › Influenzavirus A

Protein attributes

Sequence length	454 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic linkages of terminal sialic acid residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates. Spearmint SPM001860
Subunit structure	Homotetramer By similarity. Spearmint SPM001860

Ontologies

Keywords
Cellular component	Cell membrane Spearmint SPM001860 Membrane Virion Spearmint SPM001860
Domain	Transmembrane Spearmint SPM001860
Molecular function	Glycosidase Spearmint SPM001860 Hydrolase
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	apical plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW virion membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	exo-alpha-sialidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAF02314.1

Sequences

	Sequence		Length	Mass (Da)
	Q9PZM6-1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: FEC0FB03F35849AC	FASTA	454	49,847
	10 20 30 40 50 60 VIGIVSLMLQ IGNIISIWVS HSIQTGNQHQ PEPCNQSIIT YENNTWVNQT YVNISNTNFL 70 80 90 100 110 120 TEQAVTSVTL AGNSSLCPIS GWAIHSKDNG IRIGSKGDVF VIREPFISCS HLECRTFFLT 130 140 150 160 170 180 QGALLNDKHS NGTVKDRSPY RTLMSCPVGE APSPYNSRFE SVAWSASACH DGISWLTIGI 190 200 210 220 230 240 SGPDNGAVAV LKYNGIITDT IKSWRNNILR TQESECACVN GSCFTVMTDG PSNGQASYKI 250 260 270 280 290 300 FKIEKGKVVK SVELNAPNYH YEECSCYPDA GEITCVCRDN WHGSNRPWVS FNQNLEYQIG 310 320 330 340 350 360 YICSGVFGDN PRPNDGTGSC GPVSSNGAYG VKGFSFKYGN GVWIGRTKST SSRSGFEMIW 370 380 390 400 410 420 DPNGWTETDS SFSMKQDIVA ITDWSGYSGS FVQHPELTGL NCMRPCFWVE LIRGRPKENT 430 440 450 IWTSGSSISF CGVNSDTVGW SWPDGAELPF TIDK

References

[1]	"Rapid evolution of H5N1 influenza viruses in chickens in Hong Kong." Zhou N.N., Shortridge K.F., Claas E.C.J., Krauss S.L., Webster R.G. J. Virol. 73:3366-3374(1999) [PubMed: 10074191] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: A/Aquatic Bird/Hong Kong/m603/98 EMBL AAF02314.1.
[2]	"Evolution of H5N1 avian influenza viruses in Asia." World Health Organization Global Influenza Program Surveillance Network Emerg. Infect. Dis. 11:1515-1521(2005) [PubMed: 16318689] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: A/Aquatic Bird/Hong Kong/m603/98 EMBL AAF02314.1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF098551 Viral cRNA. Translation: AAF02314.1.
3D structure databases
HSSP	HSSP built from PDB template 1F8E based on UniProtKB P03472.
SMR	Q9PZM6. Positions 68-452.
ModBase	Search...
Protein family/group databases
CAZy	GH34. Glycoside Hydrolase Family 34.
Family and domain databases
InterPro	IPR001860. Glyco_hydro_34. [Graphical view]
Pfam	PF00064. Neur. 1 hit. [Graphical view]
ProDom	PD000431. Glyco_hydro_34. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

Q9PZM6_9INFA

Accession

Primary (citable) accession number: Q9PZM6

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	May 5, 2009
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)