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Q9PY95 (NSP3_ROTHC) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Non-structural protein 3

Short name=NSP3

Cleaved into the following 2 chains:

  1. p38
  2. p8
OrganismRotavirus C (isolate Human/United Kingdom/Bristol/1989) (RV-C) [Reference proteome]
Taxonomic identifier31567 [NCBI]
Taxonomic lineageVirusesdsRNA virusesReoviridaeSedoreovirinaeRotavirus
Virus hostHomo sapiens (Human) [TaxID: 9606]

Protein attributes

Sequence length402 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the rotavirus C NSP3 family.

Contains 1 DRBM (double-stranded RNA-binding) domain.

Ontologies

Keywords
   LigandRNA-binding
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular_functionRNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 402402Non-structural protein 3
PRO_0000369885
Chain1 – 333333p38 By similarity
PRO_0000369886
Chain334 – 40269p8 By similarity
PRO_0000369887

Regions

Domain334 – 40269DRBM

Sites

Site333 – 3342Cleavage; by autolysis Potential

Sequences

Sequence LengthMass (Da)Tools
Q9PY95 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: D2E3D7F14B6E2E23

FASTA40245,328
        10         20         30         40         50         60 
MATQASVEWI FNVAGSAASS SLDKAIKDAG GSENFSKYVI TKFYDNYKDC IDDSGVYNAC 

        70         80         90        100        110        120 
IGRAKTIDKA LNDPKVAERN EEWYTNVATI SRLDLELAEL KLMLSNLGIK REERVLNSMF 

       130        140        150        160        170        180 
SVVREKGRSS NVIMMKQNAV KMIEEGKLKI KVERNETYTE SLKNKIEELE CIIDAFEKGK 

       190        200        210        220        230        240 
DITIDLDAMN GEVKLDGNSC SYNSTAALVS TILGTPIKMY NESGQPLFDV GNYMNPKNII 

       250        260        270        280        290        300 
EKMIELEIPI FKSDYRNNES PDFDSWNERS NLKIVSVNDC HAICIFKFEN NWWCFDDGRL 

       310        320        330        340        350        360 
KKHNGAGYPL IVANSKFQID KILISGDIEL NPGPDILVTL NDYITKYQLK LECTFDIFLE 

       370        380        390        400 
DDGSITYTCY MKLESAEAIG SGRSKKEAKR IAAYDILDQL GI 

« Hide

References

[1]"Molecular characterization of human group C rotavirus genes 6, 7 and 9."
James V.L., Lambden P.R., Deng Y., Caul E.O., Clarke I.N.
J. Gen. Virol. 80:3181-3187(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ132203 Genomic RNA. Translation: CAB52751.1.
RefSeqYP_392486.1. NC_007543.1.

3D structure databases

ProteinModelPortalQ9PY95.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3773128.

Family and domain databases

Gene3D3.30.160.20. 1 hit.
InterProIPR014720. dsRNA-bd_dom.
IPR002873. Rotavirus_NSP3.
[Graphical view]
PfamPF00035. dsrm. 1 hit.
PF01665. Rota_NSP3. 1 hit.
[Graphical view]
SMARTSM00358. DSRM. 1 hit.
[Graphical view]
SUPFAMSSF69903. SSF69903. 1 hit.
PROSITEPS50137. DS_RBD. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameNSP3_ROTHC
AccessionPrimary (citable) accession number: Q9PY95
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: May 1, 2000
Last modified: October 16, 2013
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families