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Protein

Non-structural protein 3

Gene
N/A
Organism
Rotavirus C (isolate RVC/Human/United Kingdom/Bristol/1989) (RV-C)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

May play a role in stimulating the translation of viral mRNAs.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRNA-binding
Biological processTranslation regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Non-structural protein 3UniRule annotation
Short name:
NSP3UniRule annotation
Alternative name(s):
NCVP4UniRule annotation
Non-structural RNA-binding protein 34UniRule annotation
Short name:
NS34UniRule annotation
Cleaved into the following 2 chains:
OrganismiRotavirus C (isolate RVC/Human/United Kingdom/Bristol/1989) (RV-C)
Taxonomic identifieri31567 [NCBI]
Taxonomic lineageiVirusesdsRNA virusesReoviridaeSedoreovirinaeRotavirus
Virus hostiHomo sapiens (Human) [TaxID: 9606]
Proteomesi

Subcellular locationi

  • Host cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Host cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003698851 – 402Non-structural protein 3Add BLAST402
ChainiPRO_00003698861 – 333p38By similarityAdd BLAST333
ChainiPRO_0000369887334 – 402p8By similarityAdd BLAST69

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei333 – 334Cleavage; by autolysisSequence analysis2

Proteomic databases

PRIDEiQ9PY95

Structurei

3D structure databases

ProteinModelPortaliQ9PY95
SMRiQ9PY95
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini334 – 402DRBMPROSITE-ProRule annotationAdd BLAST69

Sequence similaritiesi

Belongs to the rotavirus NSP3 family.UniRule annotation

Phylogenomic databases

OrthoDBiVOG0900009V

Family and domain databases

HAMAPiMF_04090 ROTA_NSP3, 1 hit
InterProiView protein in InterPro
IPR014720 dsRBD_dom
IPR036082 NSP3_sf
IPR002873 Rotavirus_NSP3
PfamiView protein in Pfam
PF00035 dsrm, 1 hit
PF01665 Rota_NSP3, 1 hit
SMARTiView protein in SMART
SM00358 DSRM, 1 hit
SUPFAMiSSF69903 SSF69903, 1 hit
PROSITEiView protein in PROSITE
PS50137 DS_RBD, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9PY95-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATQASVEWI FNVAGSAASS SLDKAIKDAG GSENFSKYVI TKFYDNYKDC
60 70 80 90 100
IDDSGVYNAC IGRAKTIDKA LNDPKVAERN EEWYTNVATI SRLDLELAEL
110 120 130 140 150
KLMLSNLGIK REERVLNSMF SVVREKGRSS NVIMMKQNAV KMIEEGKLKI
160 170 180 190 200
KVERNETYTE SLKNKIEELE CIIDAFEKGK DITIDLDAMN GEVKLDGNSC
210 220 230 240 250
SYNSTAALVS TILGTPIKMY NESGQPLFDV GNYMNPKNII EKMIELEIPI
260 270 280 290 300
FKSDYRNNES PDFDSWNERS NLKIVSVNDC HAICIFKFEN NWWCFDDGRL
310 320 330 340 350
KKHNGAGYPL IVANSKFQID KILISGDIEL NPGPDILVTL NDYITKYQLK
360 370 380 390 400
LECTFDIFLE DDGSITYTCY MKLESAEAIG SGRSKKEAKR IAAYDILDQL

GI
Length:402
Mass (Da):45,328
Last modified:May 1, 2000 - v1
Checksum:iD2E3D7F14B6E2E23
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ132203 Genomic RNA Translation: CAB52751.1
RefSeqiYP_392486.1, NC_007543.1

Genome annotation databases

GeneIDi3773128
KEGGivg:3773128

Entry informationi

Entry nameiNSP3_ROTHC
AccessioniPrimary (citable) accession number: Q9PY95
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: May 1, 2000
Last modified: May 23, 2018
This is version 65 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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