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Q9PY95

- NSP3_ROTHC

UniProt

Q9PY95 - NSP3_ROTHC

Protein

Non-structural protein 3

Gene
N/A
Organism
Rotavirus C (isolate Human/United Kingdom/Bristol/1989) (RV-C)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 52 (01 Oct 2014)
      Sequence version 1 (01 May 2000)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sitei333 – 3342Cleavage; by autolysisSequence Analysis

    GO - Molecular functioni

    1. RNA binding Source: UniProtKB-KW

    Keywords - Ligandi

    RNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Non-structural protein 3
    Short name:
    NSP3
    Cleaved into the following 2 chains:
    OrganismiRotavirus C (isolate Human/United Kingdom/Bristol/1989) (RV-C)
    Taxonomic identifieri31567 [NCBI]
    Taxonomic lineageiVirusesdsRNA virusesReoviridaeSedoreovirinaeRotavirus
    Virus hostiHomo sapiens (Human) [TaxID: 9606]
    ProteomesiUP000007664: Genome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 402402Non-structural protein 3PRO_0000369885Add
    BLAST
    Chaini1 – 333333p38By similarityPRO_0000369886Add
    BLAST
    Chaini334 – 40269p8By similarityPRO_0000369887Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliQ9PY95.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini334 – 40269DRBMPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the rotavirus C NSP3 family.Curated
    Contains 1 DRBM (double-stranded RNA-binding) domain.PROSITE-ProRule annotation

    Family and domain databases

    Gene3Di3.30.160.20. 1 hit.
    InterProiIPR014720. dsRNA-bd_dom.
    IPR002873. Rotavirus_NSP3.
    [Graphical view]
    PfamiPF00035. dsrm. 1 hit.
    PF01665. Rota_NSP3. 1 hit.
    [Graphical view]
    SMARTiSM00358. DSRM. 1 hit.
    [Graphical view]
    SUPFAMiSSF69903. SSF69903. 1 hit.
    PROSITEiPS50137. DS_RBD. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q9PY95-1 [UniParc]FASTAAdd to Basket

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    MATQASVEWI FNVAGSAASS SLDKAIKDAG GSENFSKYVI TKFYDNYKDC    50
    IDDSGVYNAC IGRAKTIDKA LNDPKVAERN EEWYTNVATI SRLDLELAEL 100
    KLMLSNLGIK REERVLNSMF SVVREKGRSS NVIMMKQNAV KMIEEGKLKI 150
    KVERNETYTE SLKNKIEELE CIIDAFEKGK DITIDLDAMN GEVKLDGNSC 200
    SYNSTAALVS TILGTPIKMY NESGQPLFDV GNYMNPKNII EKMIELEIPI 250
    FKSDYRNNES PDFDSWNERS NLKIVSVNDC HAICIFKFEN NWWCFDDGRL 300
    KKHNGAGYPL IVANSKFQID KILISGDIEL NPGPDILVTL NDYITKYQLK 350
    LECTFDIFLE DDGSITYTCY MKLESAEAIG SGRSKKEAKR IAAYDILDQL 400
    GI 402
    Length:402
    Mass (Da):45,328
    Last modified:May 1, 2000 - v1
    Checksum:iD2E3D7F14B6E2E23
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ132203 Genomic RNA. Translation: CAB52751.1.
    RefSeqiYP_392486.1. NC_007543.1.

    Genome annotation databases

    GeneIDi3773128.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ132203 Genomic RNA. Translation: CAB52751.1 .
    RefSeqi YP_392486.1. NC_007543.1.

    3D structure databases

    ProteinModelPortali Q9PY95.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 3773128.

    Family and domain databases

    Gene3Di 3.30.160.20. 1 hit.
    InterProi IPR014720. dsRNA-bd_dom.
    IPR002873. Rotavirus_NSP3.
    [Graphical view ]
    Pfami PF00035. dsrm. 1 hit.
    PF01665. Rota_NSP3. 1 hit.
    [Graphical view ]
    SMARTi SM00358. DSRM. 1 hit.
    [Graphical view ]
    SUPFAMi SSF69903. SSF69903. 1 hit.
    PROSITEi PS50137. DS_RBD. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Molecular characterization of human group C rotavirus genes 6, 7 and 9."
      James V.L., Lambden P.R., Deng Y., Caul E.O., Clarke I.N.
      J. Gen. Virol. 80:3181-3187(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

    Entry informationi

    Entry nameiNSP3_ROTHC
    AccessioniPrimary (citable) accession number: Q9PY95
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: May 1, 2000
    Last modified: October 1, 2014
    This is version 52 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3