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Q9PY94

- NSP1_ROTHC

UniProt

Q9PY94 - NSP1_ROTHC

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Protein

Non-structural protein 1

Gene
N/A
Organism
Rotavirus C (isolate Human/United Kingdom/Bristol/1989) (RV-C)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri40 – 6930 Reviewed predictionAdd
BLAST

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. RNA binding Source: UniProtKB-KW

GO - Biological processi

  1. suppression by virus of host IRF3 activity Source: UniProtKB-KW
  2. suppression by virus of host IRF7 activity Source: UniProtKB-KW
  3. suppression by virus of host NF-kappaB transcription factor activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Host-virus interaction, Inhibition of host innate immune response by virus, Inhibition of host IRF3 by virus, Inhibition of host IRF7 by virus, Inhibition of host NF-kappa-B by virus, Inhibition of host RLR pathway by virus, Viral immunoevasion

Keywords - Ligandi

Metal-binding, RNA-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Non-structural protein 1
Short name:
NSP1
Alternative name(s):
NCVP2
Non-structural RNA-binding protein 53
Short name:
NS53
OrganismiRotavirus C (isolate Human/United Kingdom/Bristol/1989) (RV-C)
Taxonomic identifieri31567 [NCBI]
Taxonomic lineageiVirusesdsRNA virusesReoviridaeSedoreovirinaeRotavirus
Virus hostiHomo sapiens (Human) [TaxID: 9606]
ProteomesiUP000007664: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 394394Non-structural protein 1PRO_0000369881Add
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the rotavirus C NSP1 family.

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri40 – 6930 Reviewed predictionAdd
BLAST

Keywords - Domaini

Zinc-finger

Family and domain databases

InterProiIPR002148. Rotavirus_NSP1.
[Graphical view]
PfamiPF00981. Rota_NS53. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9PY94-1 [UniParc]FASTAAdd to Basket

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MANSFREMLY WYRKIIDRKL PCVNVNIWRR EIAYKANGIC LNCLNECKVC    50
PCDYCGIRHK CENCLNSDCF MNTNNEFNSH RWITFDEEPS QMVLFEYWIM 100
YKDYFLSKFN YNYKAQLKIL NMNKNRRFHI NESKKKALSV PITSQYLKFK 150
FNNKIYIMFG TFLTSKIQPW IQLKSLKVGY IQSLNVDRCA KLIATKGMFA 200
TNSFKSSCIT EINARRPISE CDYLIEACLC NENNEWKFSA VMGRDKIPVT 250
KSLAMKYFCK NINTELFYYG HSKCHVVSEC PRWNQQLRVL NASTLNIIFR 300
RQFMNEVVEW FENFTQLTGM HYDFIKTCVY NKVIISHFRK EIEDYINSGK 350
KISLSSVIPD GHALYTNIDI LRISLMLAID VALNRIESQQ MDVL 394
Length:394
Mass (Da):46,642
Last modified:May 1, 2000 - v1
Checksum:i4FAB1BB841EDCF29
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ132204 Genomic RNA. Translation: CAB52752.1.
RefSeqiYP_392487.1. NC_007544.1.

Genome annotation databases

GeneIDi3773134.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ132204 Genomic RNA. Translation: CAB52752.1 .
RefSeqi YP_392487.1. NC_007544.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3773134.

Family and domain databases

InterProi IPR002148. Rotavirus_NSP1.
[Graphical view ]
Pfami PF00981. Rota_NS53. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Molecular characterization of human group C rotavirus genes 6, 7 and 9."
    James V.L., Lambden P.R., Deng Y., Caul E.O., Clarke I.N.
    J. Gen. Virol. 80:3181-3187(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Entry informationi

Entry nameiNSP1_ROTHC
AccessioniPrimary (citable) accession number: Q9PY94
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: May 1, 2000
Last modified: February 19, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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