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Protein
Submitted name:

Pepsinogen C

Gene

cPgC

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei91PROSITE-ProRule annotation1
Active sitei276PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAspartyl proteasePROSITE-ProRule annotation, Hydrolase, Protease

Protein family/group databases

MEROPSiA01.003

Names & Taxonomyi

Protein namesi
Submitted name:
Pepsinogen CImported
Gene namesi
Name:cPgCImported
Synonyms:PGCImported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 26

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 16Sequence analysisAdd BLAST16
ChainiPRO_501431315617 – 389Sequence analysisAdd BLAST373

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSGALG00000003435

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000005433

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini73 – 386Peptidase A1InterPro annotationAdd BLAST314

Sequence similaritiesi

Belongs to the peptidase A1 family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG1339 Eukaryota
ENOG410XNV7 LUCA
GeneTreeiENSGT00760000118929
HOGENOMiHOG000197681
HOVERGENiHBG000482
KOiK01377
OMAiFGQNRVG
OrthoDBiEOG091G0JP7
TreeFamiTF314990

Family and domain databases

Gene3Di2.40.70.10, 2 hits
InterProiView protein in InterPro
IPR001461 Aspartic_peptidase_A1
IPR001969 Aspartic_peptidase_AS
IPR012848 Aspartic_peptidase_N
IPR033735 Gastricsin
IPR033121 PEPTIDASE_A1
IPR021109 Peptidase_aspartic_dom_sf
PANTHERiPTHR13683 PTHR13683, 1 hit
PTHR13683:SF292 PTHR13683:SF292, 1 hit
PfamiView protein in Pfam
PF07966 A1_Propeptide, 1 hit
PF00026 Asp, 1 hit
PRINTSiPR00792 PEPSIN
SUPFAMiSSF50630 SSF50630, 1 hit
PROSITEiView protein in PROSITE
PS00141 ASP_PROTEASE, 2 hits
PS51767 PEPTIDASE_A1, 1 hit

Sequencei

Sequence statusi: Complete.

Q9PWK1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKRLILTVLC LHLCEGILRV PLKKGKSIRE AMKESGVLHD YLANHRHYDP
60 70 80 90 100
AYKFFSNFAT AYEPLANNMD MSYYGEISIG TPPQNFLVLF DTGSSNLWVP
110 120 130 140 150
STLCQSQACA NHNEFDPNES STFSTQDEFF SLQYGSGSLT GIFGFDTVTI
160 170 180 190 200
QGISITNQEF GLSETEPGTS FLYSPFDGIL GLAFPSISAG GATTVMQKML
210 220 230 240 250
QENLLDFPVF SFYLSGQEGS QGGELVFGGV DPNLYTGQIT WTPVTQTTYW
260 270 280 290 300
QIGIEDFAVG GQSSGWCSQG CQGIVDTGTS LLTVPNQVFT ELMQYIGAQA
310 320 330 340 350
DDSGQYVASC SNIEYMPTIT FVISGTSFPL PPSAYMLQSN SDYCTVGIES
360 370 380
TYLPSQTGQP LWILGDVFLR VYYSIYDMGN NQVGFATAV
Length:389
Mass (Da):42,526
Last modified:May 1, 2000 - v1
Checksum:iBF95671C3A76ED78
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC164569 Genomic DNA No translation available.
AB025282 mRNA Translation: BAA76893.1
PIRiJE0371
RefSeqiNP_990208.1, NM_204877.2
UniGeneiGga.401

Genome annotation databases

EnsembliENSGALT00000005443; ENSGALP00000005433; ENSGALG00000003435
GeneIDi395690
KEGGigga:395690

Similar proteinsi

Entry informationi

Entry nameiQ9PWK1_CHICK
AccessioniPrimary (citable) accession number: Q9PWK1
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: April 25, 2018
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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