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Q9PWD3 (HXA5_MORSA) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Homeobox protein Hox-A5
Gene names
Name:hoxa5
OrganismMorone saxatilis (Striped bass)
Taxonomic identifier34816 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Euteleostei › Neoteleostei › Acanthomorpha › Acanthopterygii › Percomorpha › Perciformes › Percoidei › Moronidae › Morone

Protein attributes

Sequence length281 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis By similarity.

Subcellular location

Nucleus By similarity.

Sequence similarities

Belongs to the Antp homeobox family.

Contains 1 homeobox DNA-binding domain.

Ontologies

Keywords
   Biological processTranscription
Transcription regulation
   Cellular componentNucleus
   DomainHomeobox
   LigandDNA-binding
   Molecular functionDevelopmental protein
Gene Ontology (GO)
   Biological processmulticellular organismal development

Inferred from electronic annotation. Source: UniProtKB-KW

transcription, DNA-dependent

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentnucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionsequence-specific DNA binding

Inferred from electronic annotation. Source: InterPro

sequence-specific DNA binding transcription factor activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 281281Homeobox protein Hox-A5
PRO_0000200064

Regions

DNA binding205 – 26460Homeobox
Motif187 – 1926Antp-type hexapeptide
Compositional bias232 – 2354Poly-Arg
Compositional bias275 – 2784Poly-Gly

Sequences

Sequence LengthMass (Da)Tools
Q9PWD3 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 5726D13D47C8AE35

FASTA28131,124
        10         20         30         40         50         60 
MSSYFVNSFC GRYPNGADFQ LHNYGDHSTA NDQYRDSTAM HSSRYGYGYN GMDLTVGRAG 

        70         80         90        100        110        120 
TGHFVGNERT QGYSPSHSAA TTPSVEPVRY TQSANSTGTS SLSPPPDPLP CSSVASSSPV 

       130        140        150        160        170        180 
TETQSQHRAV KNSITTPCST PCSSSNGGTL LLNRDCVSKA SPLEEEKPAG SAPTTPQNVS 

       190        200        210        220        230        240 
DSTQPQIYPW MRKLHINHDL AGPEGKRART AYTRYQTLEL EKEFHFNRYL TRRRRIEIAH 

       250        260        270        280 
ALCLSERQIK IWFQNRRMKW KKDNKLKSMN MAAAGGGGYR P

« Hide

References

[1]"Genomic organization of the Hoxa4-Hoxa10 region from Morone saxatilis: implications for Hox gene evolution among vertebrates."
Snell E.A., Scemama J.L., Stellwag E.J.
J. Exp. Zool. 285:41-49(1999) [PubMed: 10327649] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AF089743 Genomic DNA. Translation: AAD46398.1.

3D structure databases

ProteinModelPortalQ9PWD3.
SMRQ9PWD3. Positions 185-265.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

HOVERGENHBG016849.

Family and domain databases

InterProIPR001356. Homeobox.
IPR017995. Homeobox_antennapedia.
IPR001827. Homeobox_Antennapedia_CS.
IPR017970. Homeobox_CS.
IPR020479. Homeobox_eu.
IPR009057. Homeodomain-like.
IPR012287. Homeodomain-rel.
[Graphical view]
Gene3DG3DSA:1.10.10.60. Homeodomain-rel. 1 hit.
PfamPF00046. Homeobox. 1 hit.
[Graphical view]
PRINTSPR00025. ANTENNAPEDIA.
PR00024. HOMEOBOX.
SMARTSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMSSF46689. Homeodomain_like. 1 hit.
PROSITEPS00032. ANTENNAPEDIA. 1 hit.
PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameHXA5_MORSA
AccessionPrimary (citable) accession number: Q9PWD3
Entry history
Integrated into UniProtKB/Swiss-Prot: July 11, 2001
Last sequence update: May 1, 2000
Last modified: December 14, 2011
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

Vertebrate homeotic Hox proteins

Nomenclature of vertebrate homeotic Hox proteins and list of entries

SIMILARITY comments

Index of protein domains and families

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