Q9PW72 (PDLI4_CHICK) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
PDZ and LIM domain protein 4

Alternative name(s):
LIM protein RIL
Reversion-induced LIM protein

Gene names

Name:	PDLIM4
Synonyms:	RIL

Organism

Gallus gallus (Chicken) [Reference proteome]

Taxonomic identifier

9031 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Sauropsida › Sauria › Archosauria › Dinosauria › Saurischia › Theropoda › Coelurosauria › Aves › Neognathae › Galliformes › Phasianidae › Phasianinae › Gallus

Protein attributes

Sequence length	330 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Negative regulator of cell growth.
Sequence similarities	Contains 1 LIM zinc-binding domain. Contains 1 PDZ (DHR) domain.

Ontologies

Keywords
Domain	LIM domain
Ligand	Metal-binding Zinc
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular_function	zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 330	330	PDZ and LIM domain protein 4		PRO_0000075876
Regions
	Domain	8 – 84	77	PDZ
	Domain	255 – 305	51	LIM zinc-binding

Sequences

	Sequence		Length	Mass (Da)
	Q9PW72 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 2C0E0B404301E404	FASTA	330	35,839
	10 20 30 40 50 60 MPHSVALRGP SPWGFRLVGG KDFSTPLTIS RINPGSKAAL ANLCPGDIIL AINGESTEAM 70 80 90 100 110 120 THLEAQNKIK ACVEQLLLSV SRAEERSWSP PILEDGKAQA YRINIEPEPQ DNGPAVGKRP 130 140 150 160 170 180 MPHAAGGSPV DSRPALSLQH PQPSRPHASS SADAALPLQL SGLHISPSQS TDPLKSLPRN 190 200 210 220 230 240 RNGIDVESDV YKMLQDYERP ASEPKQSGSF RYLQGMLEAG ENGEKLDRLS NPRSIKPAGP 250 260 270 280 290 300 KLGAAMSGLQ MLPECTRCGN GIVGTIVKAR DKLYHPECFM CDDCGLNLKQ RGYFFIEEQL 310 320 330 YCETHAKERV KPPEGYDVVA VYPNAKVELV

References

[1]	"Identification and characterization of genes upregulated in cells transformed by v-Jun." Fu S.-L., Waha A., Vogt P.K. Oncogene 19:3537-3545(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: White leghorn.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF167295 mRNA. Translation: AAD46655.1.
IPI	IPI00571915.
RefSeq	NP_990170.1. NM_204839.2.
UniGene	Gga.7467.
3D structure databases
ProteinModelPortal	Q9PW72.
SMR	Q9PW72. Positions 1-87, 250-313.
ModBase	Search...
Proteomic databases
PaxDb	Q9PW72.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSGALT00000010806; ENSGALP00000010792; ENSGALG00000006683.
GeneID	395643.
KEGG	gga:395643.
Organism-specific databases
CTD	8572.
Phylogenomic databases
eggNOG	NOG297766.
GeneTree	ENSGT00590000082980.
HOGENOM	HOG000290704.
HOVERGEN	HBG061371.
InParanoid	Q9PW72.
OMA	RSRDCGV.
OrthoDB	EOG48KRBW.
Gene expression databases
ArrayExpress	Q9PW72.
Family and domain databases
Gene3D	2.10.110.10. 1 hit.
InterPro	IPR001478. PDZ. IPR001781. Znf_LIM. [Graphical view]
Pfam	PF00412. LIM. 1 hit. PF00595. PDZ. 1 hit. [Graphical view]
SMART	SM00132. LIM. 1 hit. SM00228. PDZ. 1 hit. [Graphical view]
SUPFAM	SSF50156. PDZ. 1 hit.
PROSITE	PS00478. LIM_DOMAIN_1. 1 hit. PS50023. LIM_DOMAIN_2. 1 hit. PS50106. PDZ. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	20815716.

Entry information

Entry name

PDLI4_CHICK

Accession

Primary (citable) accession number: Q9PW72

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 21, 2001
Last sequence update:	May 1, 2000
Last modified:	April 3, 2013
This is version 70 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program