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Q9PVS4

- HXC4_ORYLA

UniProt

Q9PVS4 - HXC4_ORYLA

Protein

Homeobox protein Hox-C4

Gene

hoxc4

Organism
Oryzias latipes (Medaka fish) (Japanese ricefish)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 91 (01 Oct 2014)
      Sequence version 1 (01 May 2000)
      Previous versions | rss
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    Functioni

    Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.By similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    DNA bindingi154 – 21360HomeoboxPROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. sequence-specific DNA binding Source: InterPro
    2. sequence-specific DNA binding transcription factor activity Source: InterPro

    GO - Biological processi

    1. multicellular organismal development Source: UniProtKB-KW
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Developmental protein

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Homeobox protein Hox-C4
    Gene namesi
    Name:hoxc4
    Synonyms:hoxc4a
    OrganismiOryzias latipes (Medaka fish) (Japanese ricefish)
    Taxonomic identifieri8090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataOvalentariaAtherinomorphaeBeloniformesAdrianichthyidaeOryziinaeOryzias
    ProteomesiUP000001038: Chromosome 7

    Subcellular locationi

    Nucleus PROSITE-ProRule annotation

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 261261Homeobox protein Hox-C4PRO_0000200168Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliQ9PVS4.
    SMRiQ9PVS4. Positions 131-214.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi133 – 1386Antp-type hexapeptide

    Sequence similaritiesi

    Contains 1 homeobox DNA-binding domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Homeobox

    Phylogenomic databases

    eggNOGiNOG314883.
    GeneTreeiENSGT00750000117269.
    HOVERGENiHBG016849.
    InParanoidiQ9PVS4.
    KOiK09304.
    OMAiERQYNCA.
    OrthoDBiEOG780RP4.
    TreeFamiTF352857.

    Family and domain databases

    Gene3Di1.10.10.60. 1 hit.
    InterProiIPR017995. Homeobox_antennapedia.
    IPR001827. Homeobox_Antennapedia_CS.
    IPR017970. Homeobox_CS.
    IPR001356. Homeobox_dom.
    IPR020479. Homeobox_metazoa.
    IPR009057. Homeodomain-like.
    [Graphical view]
    PfamiPF00046. Homeobox. 1 hit.
    [Graphical view]
    PRINTSiPR00025. ANTENNAPEDIA.
    PR00024. HOMEOBOX.
    SMARTiSM00389. HOX. 1 hit.
    [Graphical view]
    SUPFAMiSSF46689. SSF46689. 1 hit.
    PROSITEiPS00032. ANTENNAPEDIA. 1 hit.
    PS00027. HOMEOBOX_1. 1 hit.
    PS50071. HOMEOBOX_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9PVS4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIMSSYLMES NYIDPKFPPC EEYSQNNYIP DSPEYYSRAR DTGYQHHHQE    50
    LYPPRASYQE RQYNCASIPE PDTPRGHGIP HSAHLLAGKG QPASCETPQL 100
    SMSPATPPAA ASACNQATPE HPNSTASSKQ PVVYPWMKKI HVSTVNSGYN 150
    GTEPKRSRTA YTRQQVLELE KEFHYNRYLT RRRRIEIAHT LVLSERQIKI 200
    WFQNRRMKWK KDHRLPNTKV RSSSSGSNTS SAAGGVAAAS ATNSGPDELS 250
    GAQHGEDITR L 261
    Length:261
    Mass (Da):29,373
    Last modified:May 1, 2000 - v1
    Checksum:i01890A19997E2B94
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB026955 mRNA. Translation: BAA86238.1.
    RefSeqiNP_001098348.1. NM_001104878.2.
    UniGeneiOla.24.

    Genome annotation databases

    EnsembliENSORLT00000009979; ENSORLP00000009978; ENSORLG00000007955.
    GeneIDi100125418.
    KEGGiola:100125418.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB026955 mRNA. Translation: BAA86238.1 .
    RefSeqi NP_001098348.1. NM_001104878.2.
    UniGenei Ola.24.

    3D structure databases

    ProteinModelPortali Q9PVS4.
    SMRi Q9PVS4. Positions 131-214.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSORLT00000009979 ; ENSORLP00000009978 ; ENSORLG00000007955 .
    GeneIDi 100125418.
    KEGGi ola:100125418.

    Organism-specific databases

    CTDi 30345.

    Phylogenomic databases

    eggNOGi NOG314883.
    GeneTreei ENSGT00750000117269.
    HOVERGENi HBG016849.
    InParanoidi Q9PVS4.
    KOi K09304.
    OMAi ERQYNCA.
    OrthoDBi EOG780RP4.
    TreeFami TF352857.

    Family and domain databases

    Gene3Di 1.10.10.60. 1 hit.
    InterProi IPR017995. Homeobox_antennapedia.
    IPR001827. Homeobox_Antennapedia_CS.
    IPR017970. Homeobox_CS.
    IPR001356. Homeobox_dom.
    IPR020479. Homeobox_metazoa.
    IPR009057. Homeodomain-like.
    [Graphical view ]
    Pfami PF00046. Homeobox. 1 hit.
    [Graphical view ]
    PRINTSi PR00025. ANTENNAPEDIA.
    PR00024. HOMEOBOX.
    SMARTi SM00389. HOX. 1 hit.
    [Graphical view ]
    SUPFAMi SSF46689. SSF46689. 1 hit.
    PROSITEi PS00032. ANTENNAPEDIA. 1 hit.
    PS00027. HOMEOBOX_1. 1 hit.
    PS50071. HOMEOBOX_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Hox genes of the medakafish Oryzias latipes."
      Kondo S., Naruse K., Shima A.
      Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].

    Entry informationi

    Entry nameiHXC4_ORYLA
    AccessioniPrimary (citable) accession number: Q9PVS4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 27, 2002
    Last sequence update: May 1, 2000
    Last modified: October 1, 2014
    This is version 91 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Vertebrate homeotic Hox proteins
      Nomenclature of vertebrate homeotic Hox proteins and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3