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Q9PVS4

- HXC4_ORYLA

UniProt

Q9PVS4 - HXC4_ORYLA

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Protein

Homeobox protein Hox-C4

Gene

hoxc4

Organism
Oryzias latipes (Medaka fish) (Japanese ricefish)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi154 – 21360HomeoboxPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  1. sequence-specific DNA binding Source: InterPro
  2. sequence-specific DNA binding transcription factor activity Source: InterPro

GO - Biological processi

  1. multicellular organismal development Source: UniProtKB-KW
  2. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Developmental protein

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Homeobox protein Hox-C4
Gene namesi
Name:hoxc4
Synonyms:hoxc4a
OrganismiOryzias latipes (Medaka fish) (Japanese ricefish)
Taxonomic identifieri8090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataOvalentariaAtherinomorphaeBeloniformesAdrianichthyidaeOryziinaeOryzias
ProteomesiUP000001038: Chromosome 7

Subcellular locationi

Nucleus PROSITE-ProRule annotation

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 261261Homeobox protein Hox-C4PRO_0000200168Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ9PVS4.
SMRiQ9PVS4. Positions 131-214.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi133 – 1386Antp-type hexapeptide

Sequence similaritiesi

Contains 1 homeobox DNA-binding domain.PROSITE-ProRule annotation

Keywords - Domaini

Homeobox

Phylogenomic databases

eggNOGiNOG314883.
GeneTreeiENSGT00760000118945.
HOVERGENiHBG016849.
InParanoidiQ9PVS4.
KOiK09304.
OMAiERQYNCA.
OrthoDBiEOG780RP4.
TreeFamiTF352857.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR017995. Homeobox_antennapedia.
IPR001827. Homeobox_Antennapedia_CS.
IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR020479. Homeobox_metazoa.
IPR009057. Homeodomain-like.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
[Graphical view]
PRINTSiPR00025. ANTENNAPEDIA.
PR00024. HOMEOBOX.
SMARTiSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00032. ANTENNAPEDIA. 1 hit.
PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9PVS4 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIMSSYLMES NYIDPKFPPC EEYSQNNYIP DSPEYYSRAR DTGYQHHHQE
60 70 80 90 100
LYPPRASYQE RQYNCASIPE PDTPRGHGIP HSAHLLAGKG QPASCETPQL
110 120 130 140 150
SMSPATPPAA ASACNQATPE HPNSTASSKQ PVVYPWMKKI HVSTVNSGYN
160 170 180 190 200
GTEPKRSRTA YTRQQVLELE KEFHYNRYLT RRRRIEIAHT LVLSERQIKI
210 220 230 240 250
WFQNRRMKWK KDHRLPNTKV RSSSSGSNTS SAAGGVAAAS ATNSGPDELS
260
GAQHGEDITR L
Length:261
Mass (Da):29,373
Last modified:May 1, 2000 - v1
Checksum:i01890A19997E2B94
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB026955 mRNA. Translation: BAA86238.1.
RefSeqiNP_001098348.1. NM_001104878.2.
UniGeneiOla.24.

Genome annotation databases

EnsembliENSORLT00000009979; ENSORLP00000009978; ENSORLG00000007955.
GeneIDi100125418.
KEGGiola:100125418.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB026955 mRNA. Translation: BAA86238.1 .
RefSeqi NP_001098348.1. NM_001104878.2.
UniGenei Ola.24.

3D structure databases

ProteinModelPortali Q9PVS4.
SMRi Q9PVS4. Positions 131-214.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSORLT00000009979 ; ENSORLP00000009978 ; ENSORLG00000007955 .
GeneIDi 100125418.
KEGGi ola:100125418.

Organism-specific databases

CTDi 30345.

Phylogenomic databases

eggNOGi NOG314883.
GeneTreei ENSGT00760000118945.
HOVERGENi HBG016849.
InParanoidi Q9PVS4.
KOi K09304.
OMAi ERQYNCA.
OrthoDBi EOG780RP4.
TreeFami TF352857.

Family and domain databases

Gene3Di 1.10.10.60. 1 hit.
InterProi IPR017995. Homeobox_antennapedia.
IPR001827. Homeobox_Antennapedia_CS.
IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR020479. Homeobox_metazoa.
IPR009057. Homeodomain-like.
[Graphical view ]
Pfami PF00046. Homeobox. 1 hit.
[Graphical view ]
PRINTSi PR00025. ANTENNAPEDIA.
PR00024. HOMEOBOX.
SMARTi SM00389. HOX. 1 hit.
[Graphical view ]
SUPFAMi SSF46689. SSF46689. 1 hit.
PROSITEi PS00032. ANTENNAPEDIA. 1 hit.
PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Hox genes of the medakafish Oryzias latipes."
    Kondo S., Naruse K., Shima A.
    Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiHXC4_ORYLA
AccessioniPrimary (citable) accession number: Q9PVS4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 27, 2002
Last sequence update: May 1, 2000
Last modified: October 29, 2014
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Vertebrate homeotic Hox proteins
    Nomenclature of vertebrate homeotic Hox proteins and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3