ID   HXD9_ORYLA              Reviewed;         271 AA.
AC   Q9PVR2;
DT   27-MAY-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   24-JAN-2024, entry version 111.
DE   RecName: Full=Homeobox protein Hox-D9;
GN   Name=hoxd9; Synonyms=hoxd9a;
OS   Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC   Oryzias.
OX   NCBI_TaxID=8090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Kondo S., Naruse K., Shima A.;
RT   "Hox genes of the medakafish Oryzias latipes.";
RL   Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Sequence-specific transcription factor which is part of a
CC       developmental regulatory system that provides cells with specific
CC       positional identities on the anterior-posterior axis. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
CC   -!- SIMILARITY: Belongs to the Abd-B homeobox family. {ECO:0000305}.
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DR   EMBL; AB026967; BAA86250.1; -; mRNA.
DR   RefSeq; NP_001188420.1; NM_001201491.1.
DR   AlphaFoldDB; Q9PVR2; -.
DR   SMR; Q9PVR2; -.
DR   GeneID; 100529156; -.
DR   KEGG; ola:100529156; -.
DR   CTD; 30350; -.
DR   eggNOG; KOG0487; Eukaryota.
DR   InParanoid; Q9PVR2; -.
DR   OrthoDB; 728401at2759; -.
DR   Proteomes; UP000001038; Unplaced.
DR   Proteomes; UP000265180; Chromosome 9.
DR   Proteomes; UP000265200; Chromosome 9.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IBA:GO_Central.
DR   GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; IBA:GO_Central.
DR   GO; GO:0009954; P:proximal/distal pattern formation; IBA:GO_Central.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   CDD; cd00086; homeodomain; 1.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR017970; Homeobox_CS.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR020479; Homeobox_metazoa.
DR   InterPro; IPR006711; Hox9_activation_N.
DR   InterPro; IPR017112; HXA9/HXB9/HXC9.
DR   PANTHER; PTHR45970; AGAP004664-PA; 1.
DR   PANTHER; PTHR45970:SF4; HOMEOBOX PROTEIN HOX-D9; 1.
DR   Pfam; PF00046; Homeodomain; 1.
DR   Pfam; PF04617; Hox9_act; 1.
DR   PIRSF; PIRSF037109; Homeobox_Hox9; 1.
DR   PRINTS; PR00024; HOMEOBOX.
DR   SMART; SM00389; HOX; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   PROSITE; PS00027; HOMEOBOX_1; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   2: Evidence at transcript level;
KW   Developmental protein; DNA-binding; Homeobox; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..271
FT                   /note="Homeobox protein Hox-D9"
FT                   /id="PRO_0000200225"
FT   DNA_BIND        203..262
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT   REGION          161..195
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        164..187
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   271 AA;  30810 MW;  72E0BF3546616478 CRC64;
     MSRKRSKMSS SGTISNYYVD GVMAQEPEDV YAPRLIQASH TVTPRPSGAG DNADFSSCNF
     APKPGVFSSS WSSVHPQGIY HPYVHHHHQP HLSATDGRYV GVRPWMEPIS NHVSFAGFHP
     SNTRPYGAKP DVLPAKVPEC DTLEPEARPV PAEFSCGGAL GAEKVTKEQR RASEISSHGE
     PKDEKQQLDP NNPAANWIHA RSTRKKRCPY TKYQTLELEK EFLYNMYLTR DRRFEVARIL
     SLTERQVKIW FQNRRMKMKK MNREKGGKDQ L
//