Q9PVR2 (HXD9_ORYLA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Homeobox protein Hox-D9

Gene names

Name:	hoxd9
Synonyms:	hoxd9a

Organism

Oryzias latipes (Medaka fish) (Japanese ricefish) [Reference proteome]

Taxonomic identifier

8090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Actinopterygii › Actinopteri › Neopterygii › Teleostei › Elopocephala › Clupeocephala › Euteleostei › Neognathi › Neoteleostei › Eurypterygii › Ctenosquamata › Acanthomorpha › Euacanthomorpha › Holacanthopterygii › Acanthopterygii › Euacanthopterygii › Percomorpha › Smegmamorpha › Atherinomorpha › Beloniformes › Adrianichthyoidei › Adrianichthyidae › Oryziinae › Oryzias

Protein attributes

Sequence length	271 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis By similarity.
Subcellular location	Nucleus By similarity.
Sequence similarities	Belongs to the Abd-B homeobox family. Contains 1 homeobox DNA-binding domain.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Cellular component	Nucleus
Domain	Homeobox
Ligand	DNA-binding
Molecular function	Developmental protein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	multicellular organismal development Inferred from electronic annotation. Source: UniProtKB-KW transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 271	271	Homeobox protein Hox-D9		PRO_0000200225
Regions
	DNA binding	203 – 262	60	Homeobox

Sequences

	Sequence		Length	Mass (Da)
	Q9PVR2 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 72E0BF3546616478	FASTA	271	30,810
	10 20 30 40 50 60 MSRKRSKMSS SGTISNYYVD GVMAQEPEDV YAPRLIQASH TVTPRPSGAG DNADFSSCNF 70 80 90 100 110 120 APKPGVFSSS WSSVHPQGIY HPYVHHHHQP HLSATDGRYV GVRPWMEPIS NHVSFAGFHP 130 140 150 160 170 180 SNTRPYGAKP DVLPAKVPEC DTLEPEARPV PAEFSCGGAL GAEKVTKEQR RASEISSHGE 190 200 210 220 230 240 PKDEKQQLDP NNPAANWIHA RSTRKKRCPY TKYQTLELEK EFLYNMYLTR DRRFEVARIL 250 260 270 SLTERQVKIW FQNRRMKMKK MNREKGGKDQ L

References

[1]	"Hox genes of the medakafish Oryzias latipes." Kondo S., Naruse K., Shima A. Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB026967 mRNA. Translation: BAA86250.1.
RefSeq	NP_001188420.1. NM_001201491.1.
UniGene	Ola.31.
3D structure databases
ProteinModelPortal	Q9PVR2.
SMR	Q9PVR2. Positions 191-266.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	100529156.
KEGG	ola:100529156.
Organism-specific databases
CTD	30350.
Phylogenomic databases
eggNOG	NOG286554.
HOGENOM	HOG000231180.
HOVERGEN	HBG016849.
KO	K09294.
Family and domain databases
Gene3D	1.10.10.60. 1 hit.
InterPro	IPR017970. Homeobox_CS. IPR017112. Homeobox_Hox9. IPR020479. Homeobox_metazoa. IPR001356. Homeodomain. IPR009057. Homeodomain-like. IPR006711. Hox9_activation_N. [Graphical view]
Pfam	PF00046. Homeobox. 1 hit. PF04617. Hox9_act. 1 hit. [Graphical view]
PIRSF	PIRSF037109. Homeobox_Hox9. 1 hit.
PRINTS	PR00024. HOMEOBOX.
SMART	SM00389. HOX. 1 hit. [Graphical view]
SUPFAM	SSF46689. Homeodomain_like. 1 hit.
PROSITE	PS00027. HOMEOBOX_1. 1 hit. PS50071. HOMEOBOX_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

HXD9_ORYLA

Accession

Primary (citable) accession number: Q9PVR2

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 27, 2002
Last sequence update:	May 1, 2000
Last modified:	May 1, 2013
This is version 74 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program