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Protein
Submitted name:

Fli-1 protein

Gene

fli1a

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • angiogenesis Source: ZFIN
  • blood vessel morphogenesis Source: ZFIN
  • cell differentiation Source: GO_Central
  • positive regulation of DNA binding transcription factor activity Source: ZFIN
  • regulation of transcription by RNA polymerase II Source: GO_Central

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Fli-1 proteinImported
Submitted name:
Fli-1 proto-oncogene, ETS transcription factor aImported
Submitted name:
Friend leukemia integration 1aImported
Gene namesi
Name:fli1aImported
Synonyms:fli-1Imported, fli1Imported
ORF Names:CH211-241L24.8-001Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 18

Organism-specific databases

ZFINiZDB-GENE-980526-426 fli1a

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSDARG00000054632

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000071331

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini111 – 197PNTInterPro annotationAdd BLAST87
Domaini280 – 360ETSInterPro annotationAdd BLAST81

Sequence similaritiesi

Belongs to the ETS family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3806 Eukaryota
ENOG410Z0ZF LUCA
GeneTreeiENSGT00760000118907
HOGENOMiHOG000290658
HOVERGENiHBG001553
KOiK09436
OMAiNPDYGQP
OrthoDBiEOG091G0EWP
TreeFamiTF350537

Family and domain databases

CDDicd08541 SAM_PNT-FLI-1, 1 hit
Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR000418 Ets_dom
IPR035575 Fli-1
IPR003118 Pointed_dom
IPR013761 SAM/pointed_sf
IPR035573 SAM_PNT-FLI-1
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PANTHERiPTHR11849:SF161 PTHR11849:SF161, 1 hit
PfamiView protein in Pfam
PF00178 Ets, 1 hit
PF02198 SAM_PNT, 1 hit
PRINTSiPR00454 ETSDOMAIN
SMARTiView protein in SMART
SM00413 ETS, 1 hit
SM00251 SAM_PNT, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
SSF47769 SSF47769, 1 hit
PROSITEiView protein in PROSITE
PS00345 ETS_DOMAIN_1, 1 hit
PS00346 ETS_DOMAIN_2, 1 hit
PS50061 ETS_DOMAIN_3, 1 hit
PS51433 PNT, 1 hit

Sequencei

Sequence statusi: Complete.

Q9PU61-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDGTIKEALS VVSEDQSLFE PPYAAAAPLP KTDMTASGTQ DYGQTHKINP
60 70 80 90 100
IPPQQEWINQ PVRVNVKREY DHINGSRESP VDCSVGKCNK MVGGTEASQM
110 120 130 140 150
NYTGYMDEKC APPPNMTTNE RRVIVPADPS LWSPDHVRQW LDWAIKEYGL
160 170 180 190 200
QEIDTAMFHS TDGKELCKMS KDDFLRLTSV YNTEVLLSHL NYLRESSSSI
210 220 230 240 250
SYNTPSHADQ SPRLAAKDDA SYDAVRRTGW SNNMHSGKGS PTVVSQSVSK
260 270 280 290 300
NPDQPRPQPD PYQILGPTSS RLANPGSGQI QLWQFLLELL SDSANAGCIT
310 320 330 340 350
WEGTNGEFKM TDPDEVARRW GERKSKPNMN YDKLSRALRY YYDKNIMTKV
360 370 380 390 400
HGKRYAYKFD FHGIAQALQP HPTESTMYKY PSELPYVPSY HAHQQKVNFV
410 420 430 440 450
SPHPPSMPVT SSNFFGPTTP YWSSPPGGIY PNPSVPRHAN SHVPSHLGSY

Y
Length:451
Mass (Da):50,656
Last modified:May 1, 2000 - v1
Checksum:iF437D55D08E3549A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR786562 Genomic DNA No translation available.
BC066571 mRNA Translation: AAH66571.1
AJ249590 mRNA Translation: CAB56832.1
BX927076 Genomic DNA Translation: CAK04698.1
RefSeqiNP_571423.1, NM_131348.2
UniGeneiDr.78408

Genome annotation databases

EnsembliENSDART00000076861; ENSDARP00000071331; ENSDARG00000054632
GeneIDi30619
KEGGidre:30619

Similar proteinsi

Entry informationi

Entry nameiQ9PU61_DANRE
AccessioniPrimary (citable) accession number: Q9PU61
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: June 20, 2018
This is version 145 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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