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Protein
Submitted name:

Cytochrome P450

Gene

cyp3A37

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • drug metabolic process Source: AgBase
  • hormone metabolic process Source: AgBase
  • mycotoxin metabolic process Source: AgBase
  • organic hydroxy compound metabolic process Source: AgBase
  • progesterone metabolic process Source: AgBase
  • response to antibiotic Source: AgBase
  • steroid metabolic process Source: AgBase
Complete GO annotation...

Keywords - Molecular functioni

MonooxygenaseUniRule annotation, Oxidoreductase

Keywords - Ligandi

HemeUniRule annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome P450Imported
Gene namesi
Name:cyp3A37Imported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 33HelicalSequence analysisAdd BLAST22

GO - Cellular componenti

  • apical part of cell Source: AgBase
  • apical plasma membrane Source: AgBase
  • cell Source: AgBase
  • integral component of membrane Source: UniProtKB-KW
  • membrane Source: AgBase
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ9PU44.

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000007068.

Structurei

3D structure databases

ProteinModelPortaliQ9PU44.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0158. Eukaryota.
COG2124. LUCA.
HOGENOMiHOG000039127.
HOVERGENiHBG108567.
KOiK07424.
PhylomeDBiQ9PU44.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR008072. Cyt_P450_E_CYP3A.
IPR002402. Cyt_P450_E_grp-II.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00464. EP450II.
PR01689. EP450IICYP3A.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9PU44-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNFLPFFSIE TWIILLIFVV LLIIYGTWPF GLFKKLGIPG PRPLPFFGTC
60 70 80 90 100
LEYRKGFLDF DTECFQKYGK IWGIYDGRQP AVVVMDPQII KTVLVKECYS
110 120 130 140 150
TFTNRRRTDL AGVLRNAVSL AEDDQWKRLR TVLSPTFTSG KLKEMFPTMK
160 170 180 190 200
YFGEMLVKNI QKRVEKNSSV PVKDFFGSYS MDVVTSTSFG VNIDSMNNPK
210 220 230 240 250
SPFVREMQKL TKFDFFDPVF ILSFVCPFLT PLMAKMNISF FPSDAVDFFM
260 270 280 290 300
RSIDKIKKDR ERETHTGRVD FLQMMIESQK SDSNGSSDAK HSYKALSDIE
310 320 330 340 350
VLSQAFIFIF AGYEPTSNTL GYLAYQLALH PDVQQKVVNE IDTILPNKAP
360 370 380 390 400
LTYEAIMQLE YLDMAVNETL RLYPLGGRLE RTCKRDVEIN GVTIPKGTIV
410 420 430 440 450
IIPPYTLHRS PEYWPNPEEF RPERFSKENK DNIDPYTYLP FGAGPRNCIG
460 470 480 490 500
MRFALLTLKV AITAVLQHFT FQVCKETQIP LKLQSLGLTT PEKPIVLKLV

PRTNTAKA
Length:508
Mass (Da):58,218
Last modified:May 1, 2000 - v1
Checksum:iB4DA20F80494AA18
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ250337 mRNA. Translation: CAB62060.1.
RefSeqiNP_001001751.1. NM_001001751.2.
UniGeneiGga.1163.

Genome annotation databases

GeneIDi414832.
KEGGigga:414832.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ250337 mRNA. Translation: CAB62060.1.
RefSeqiNP_001001751.1. NM_001001751.2.
UniGeneiGga.1163.

3D structure databases

ProteinModelPortaliQ9PU44.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000007068.

Proteomic databases

PaxDbiQ9PU44.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi414832.
KEGGigga:414832.

Organism-specific databases

CTDi1551.

Phylogenomic databases

eggNOGiKOG0158. Eukaryota.
COG2124. LUCA.
HOGENOMiHOG000039127.
HOVERGENiHBG108567.
KOiK07424.
PhylomeDBiQ9PU44.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR008072. Cyt_P450_E_CYP3A.
IPR002402. Cyt_P450_E_grp-II.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00464. EP450II.
PR01689. EP450IICYP3A.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9PU44_CHICK
AccessioniPrimary (citable) accession number: Q9PU44
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: October 5, 2016
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.