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Q9PU40 (Q9PU40_CHICK) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:tyrosine hydroxylase EMBL CAB62388.1
OrganismGallus gallus (Chicken)
Taxonomic identifier9031 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalliformesPhasianidaePhasianinaeGallus

Protein attributes

Sequence length491 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

Ontologies

Gene Ontology (GO)
   Biological_processaromatic amino acid family metabolic process

Inferred from electronic annotation. Source: InterPro

dopamine biosynthetic process

Inferred from electronic annotation. Source: Ensembl

eating behavior

Inferred from electronic annotation. Source: Ensembl

embryonic camera-type eye morphogenesis

Inferred from electronic annotation. Source: Ensembl

epinephrine biosynthetic process

Inferred from electronic annotation. Source: Ensembl

eye photoreceptor cell development

Inferred from electronic annotation. Source: Ensembl

heart development

Inferred from electronic annotation. Source: Ensembl

learning

Inferred from electronic annotation. Source: Ensembl

locomotory behavior

Inferred from electronic annotation. Source: Ensembl

mating behavior

Inferred from electronic annotation. Source: Ensembl

memory

Inferred from electronic annotation. Source: Ensembl

norepinephrine biosynthetic process

Inferred from electronic annotation. Source: Ensembl

regulation of heart contraction

Inferred from electronic annotation. Source: Ensembl

response to ethanol

Inferred from electronic annotation. Source: Ensembl

response to hypoxia

Inferred from electronic annotation. Source: Ensembl

synaptic transmission, dopaminergic

Inferred from electronic annotation. Source: Ensembl

visual perception

Inferred from electronic annotation. Source: Ensembl

   Cellular_componentaxon

Inferred from electronic annotation. Source: Ensembl

cytoplasmic side of plasma membrane

Inferred from electronic annotation. Source: Ensembl

melanosome membrane

Inferred from electronic annotation. Source: Ensembl

nucleus

Inferred from electronic annotation. Source: Ensembl

perikaryon

Inferred from electronic annotation. Source: Ensembl

smooth endoplasmic reticulum

Inferred from electronic annotation. Source: Ensembl

   Molecular_functioniron ion binding

Inferred from electronic annotation. Source: InterPro

tyrosine 3-monooxygenase activity

Inferred from electronic annotation. Source: Ensembl

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q9PU40 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 6322F2D58E746930

FASTA49156,016
        10         20         30         40         50         60 
MPTPNISTSA AKGFRRAVSE LDSKQAEAIM SPRFIGRRQS LIEDARKERE AAAAATDAAE 

        70         80         90        100        110        120 
STETIVFEEK DGRAMLNLFF MLKGAKTSPL SRALKVFETF EAKIHHLETR LSRKPREGTA 

       130        140        150        160        170        180 
ELEYFVRCEV HSSDLNTFIS SIKRVAEDVR TTKEDKFHWF PRKICELDKC HHLVTKFDPD 

       190        200        210        220        230        240 
LDLDHPGYSD QVYRQRRKSI AEIAFHYKHG DPIPRVEYTA EETATWKEVY STLKSLYPTH 

       250        260        270        280        290        300 
ACKEYLEAFN LLEKFCGYNE NNIPQLEEVS RFLKERTGFQ LRPVAGLLSA RDFLASLAFR 

       310        320        330        340        350        360 
VFQCTQYIRH ASSPMHSPEP DCCHELLGHV PMLADKTFAQ FSQDIGLASL GATDEEIEKL 

       370        380        390        400        410        420 
ATLYWFTVEF GLCRQNGIVK AYGAGLLSSY GELIHSLSDE PEVRDFDPDA AAVQPYQDQN 

       430        440        450        460        470        480 
YQPVYFVSES FSDAKNKLRN YAAHIKRPFS VKYEPYTHSI ELLDSPQTIC HSLESVRDEL 

       490 
HSLINALNVI S 

« Hide

References

[1]"Chicken tyrosine hydroxylase gene: isolation and functional characterization of the 5' flanking region."
Carrier A., Devignes M.D., Renoir D., Auffray C.
J. Neurochem. 61:2215-2224(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
[2]"The expression of tyrosine hydroxylase and the transcription factors cPhox-2 and Cash-1: evidence for distinct inductive steps in the differentiation of chick sympathetic precursor cells."
Ernsberger U., Patzke H., Tissier-Seta J.P., Reh T., Goridis C., Rohrer H.
Mech. Dev. 52:125-136(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
[3]Ernsberger U.
Submitted (DEC-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ251387 mRNA. Translation: CAB62388.1.
PIRS40309.
RefSeqNP_990136.1. NM_204805.1.
UniGeneGga.327.

3D structure databases

ProteinModelPortalQ9PU40.
SMRQ9PU40. Positions 153-491.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING9031.ENSGALP00000010566.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID395592.
KEGGgga:395592.

Organism-specific databases

CTD7054.

Phylogenomic databases

eggNOGCOG3186.
HOGENOMHOG000233373.
HOVERGENHBG006841.
InParanoidQ9PU40.
KOK00501.
OMAELDKCHH.
OrthoDBEOG7KM5T1.
PhylomeDBQ9PU40.
TreeFamTF313327.

Family and domain databases

Gene3D1.10.800.10. 1 hit.
InterProIPR001273. ArAA_hydroxylase.
IPR018301. ArAA_hydroxylase_Fe/CU_BS.
IPR019774. Aromatic-AA_hydroxylase_C.
IPR005962. Tyr_3_mOase.
IPR019773. Tyrosine_3-monooxygenase-like.
IPR021164. Tyrosine_hydroxylase_CS.
[Graphical view]
PANTHERPTHR11473. PTHR11473. 1 hit.
PfamPF00351. Biopterin_H. 1 hit.
PF12549. TOH_N. 2 hits.
[Graphical view]
PIRSFPIRSF000336. TH. 1 hit.
PRINTSPR00372. FYWHYDRXLASE.
SUPFAMSSF56534. SSF56534. 1 hit.
TIGRFAMsTIGR01269. Tyr_3_monoox. 1 hit.
PROSITEPS00367. BH4_AAA_HYDROXYL_1. 1 hit.
PS51410. BH4_AAA_HYDROXYL_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio20815665.
PROQ9PU40.

Entry information

Entry nameQ9PU40_CHICK
AccessionPrimary (citable) accession number: Q9PU40
Entry history
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: July 9, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)