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Protein

Cytochrome P450

Gene

CYP1A9

Organism
Anguilla japonica (Japanese eel)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Cytochromes P450 are a group of heme-thiolate monooxygenases.UniRule annotation

Catalytic activityi

RH + [reduced NADPH--hemoprotein reductase] + O2 = ROH + [oxidized NADPH--hemoprotein reductase] + H2O.UniRule annotation

Cofactori

hemeUniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

MonooxygenaseUniRule annotation, Oxidoreductase

Keywords - Ligandi

HemeUniRule annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome P450UniRule annotation (EC:1.14.14.1UniRule annotation)
Gene namesi
Name:CYP1A9Imported
OrganismiAnguilla japonica (Japanese eel)Imported
Taxonomic identifieri7937 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiAnguilliformesAnguillidaeAnguilla

Subcellular locationi

  • Endoplasmic reticulum membrane UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei6 – 3126HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane, MicrosomeUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ9PTY4.
SMRiQ9PTY4. Positions 37-512.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOVERGENiHBG106944.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
IPR008066. Cyt_P450_E_grp-I_CYP1.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00463. EP450I.
PR01683. EP450ICYP1A.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9PTY4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALMNLPVVG PISVCESLVA VVTVCVVYLL LRLLSTQIPE GLKRLPGPKP
60 70 80 90 100
LPIIGNVLEL SANPHLSLTA MSERYGPVFQ IQIGMRPVVV LSGGETVRQA
110 120 130 140 150
LIKQGEEFSG RPDLHSFQYI SDGKSLAFST DQAGVWRGRR KLALSALRFF
160 170 180 190 200
STIEGSSSEY SCVLEEHISK EGMYLVEQLS TVMKANGTFD PFRHIVVSVA
210 220 230 240 250
NVICGMCFGR RYSHDDQELL SIVNLSHEFS QVASTGNPAD FIPFLRFLPS
260 270 280 290 300
RTMKAFMDMN DRFTQFVQKI VREHYISYDK NNIRDITDSL IDHCEDRKLD
310 320 330 340 350
ENSNTQISDE KVVGIVNDLF GAGFDTVSTF LSWAVMYLVT YPEIQEKLHQ
360 370 380 390 400
ELREKVGMDR LPRLTDKSNL PFLEAFITEV FRHSSFVPFT IPHCTTKNTS
410 420 430 440 450
LNGFFIPKDT CVFVNQWQVN HDPTVWKEPT DFSIERFLNA DGMSINKLEA
460 470 480 490 500
EKVMMFGLGK RRCIGEAIAR SEVFLFLAIL LQRLRFYQKP GQAPDMTPEY
510
GLTMKHKRCQ LSASLRT
Length:517
Mass (Da):58,509
Last modified:May 1, 2000 - v1
Checksum:i8750609F5BA6430E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB020414 mRNA. Translation: BAA88242.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB020414 mRNA. Translation: BAA88242.1.

3D structure databases

ProteinModelPortaliQ9PTY4.
SMRiQ9PTY4. Positions 37-512.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG106944.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
IPR008066. Cyt_P450_E_grp-I_CYP1.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00463. EP450I.
PR01683. EP450ICYP1A.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9PTY4_ANGJA
AccessioniPrimary (citable) accession number: Q9PTY4
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: February 17, 2016
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.