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Protein
Submitted name:

Small-conductance calcium-activated potassium channel

Gene

SK2

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Ion channelImported

Keywords - Biological processi

Ion transport, Transport

Enzyme and pathway databases

ReactomeiR-GGA-1296052. Ca2+ activated K+ channels.

Names & Taxonomyi

Protein namesi
Submitted name:
Small-conductance calcium-activated potassium channelImported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:SK2Imported
Synonyms:KCNN2Imported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome Z

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei108 – 127HelicalSequence analysisAdd BLAST20
Transmembranei139 – 164HelicalSequence analysisAdd BLAST26
Transmembranei185 – 204HelicalSequence analysisAdd BLAST20
Transmembranei224 – 242HelicalSequence analysisAdd BLAST19
Transmembranei279 – 299HelicalSequence analysisAdd BLAST21
Transmembranei319 – 336HelicalSequence analysisAdd BLAST18
Transmembranei348 – 368HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSGALG00000002539.

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini386 – 462CaMBDInterPro annotationAdd BLAST77

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

GeneTreeiENSGT00500000044784.
HOVERGENiHBG052241.
KOiK04943.
OMAiMESYDKH.
OrthoDBiEOG091G03YH.
TreeFamiTF315015.

Family and domain databases

InterProiIPR004178. CaM-bd_dom.
IPR015449. K_chnl_Ca-activ_SK.
IPR013099. K_chnl_dom.
[Graphical view]
PANTHERiPTHR10153. PTHR10153. 1 hit.
PfamiPF02888. CaMBD. 1 hit.
PF07885. Ion_trans_2. 1 hit.
PF03530. SK_channel. 1 hit.
[Graphical view]
PRINTSiPR01451. SKCHANNEL.
SMARTiSM01053. CaMBD. 1 hit.
[Graphical view]
SUPFAMiSSF81327. SSF81327. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9PTS9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSCRYNGGV MRPLSNLSSS RRNLHEMDAE SQPLQPPLSS PNAAGPEVVV
60 70 80 90 100
SKPEHNNSNN LALYGPAGPG PGPGGPNNGG TKPTKKKNQN IGYKLGHRRA
110 120 130 140 150
LFEKRKRLSD YALIFGMFGI VVMVIETELS WGAYTKESLY SLALKCLISL
160 170 180 190 200
STIILLGLII VYHAREIQLF MVDNGADDWR IAMTYERIFF ICLEILVCAI
210 220 230 240 250
HPIPGNYTFT WTARLAFSYA PSTATADVDI ILSIPMFLRL YLIARVMLLH
260 270 280 290 300
SKLFTDASSR SIGALNKINF NTRFVMKTLM TICPGTVLLV FSISLWIIAA
310 320 330 340 350
WTVRACERYH DQQDVTSNFL GAMWLISITF LSIGYGDMVP NTYCGKGVCL
360 370 380 390 400
LTGIMGAGCT ALVVAVVARK LELTKAEKHV HNFMMDTQLT KRVKNAAANV
410 420 430 440 450
LRETWLIYKN TKLVKKIDHA KVRKHQRKFL QAIHQLRSVK MEQRKLNDQA
460 470 480 490 500
NTLVDLAKTQ NIMYDMISDL NERSEDFEKR IVTLETKLET LIGSIQALPG
510 520 530 540 550
LISQTISQQH RDFLEAQIQN YDKHVTYSAE RSRSLSRRRR SSSTAPPTSS

ESS
Length:553
Mass (Da):62,017
Last modified:May 1, 2000 - v1
Checksum:iAE7D493EAE11074A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC189116 Genomic DNA. No translation available.
AC208879 Genomic DNA. No translation available.
AF079372 mRNA. Translation: AAF21783.1.
RefSeqiNP_990129.1. NM_204798.1.
UniGeneiGga.318.

Genome annotation databases

EnsembliENSGALT00000004004; ENSGALP00000003995; ENSGALG00000002539.
GeneIDi395579.
KEGGigga:395579.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC189116 Genomic DNA. No translation available.
AC208879 Genomic DNA. No translation available.
AF079372 mRNA. Translation: AAF21783.1.
RefSeqiNP_990129.1. NM_204798.1.
UniGeneiGga.318.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSGALT00000004004; ENSGALP00000003995; ENSGALG00000002539.
GeneIDi395579.
KEGGigga:395579.

Organism-specific databases

CTDi3781.

Phylogenomic databases

GeneTreeiENSGT00500000044784.
HOVERGENiHBG052241.
KOiK04943.
OMAiMESYDKH.
OrthoDBiEOG091G03YH.
TreeFamiTF315015.

Enzyme and pathway databases

ReactomeiR-GGA-1296052. Ca2+ activated K+ channels.

Gene expression databases

BgeeiENSGALG00000002539.

Family and domain databases

InterProiIPR004178. CaM-bd_dom.
IPR015449. K_chnl_Ca-activ_SK.
IPR013099. K_chnl_dom.
[Graphical view]
PANTHERiPTHR10153. PTHR10153. 1 hit.
PfamiPF02888. CaMBD. 1 hit.
PF07885. Ion_trans_2. 1 hit.
PF03530. SK_channel. 1 hit.
[Graphical view]
PRINTSiPR01451. SKCHANNEL.
SMARTiSM01053. CaMBD. 1 hit.
[Graphical view]
SUPFAMiSSF81327. SSF81327. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ9PTS9_CHICK
AccessioniPrimary (citable) accession number: Q9PTS9
Secondary accession number(s): E1C5A7
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: November 30, 2016
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.