ID   Q9PT63_XENLA            Unreviewed;      2065 AA.
AC   Q9PT63;
DT   01-MAY-2000, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2000, sequence version 1.
DT   03-NOV-2009, entry version 36.
DE   SubName: Full=Microtubule Associated Protein 215 kDa (XMAP215);
GN   Name=xmap215;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;
OC   Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RX   MEDLINE=20089046; PubMed=10620801; DOI=10.1038/71330;
RA   Tournebize R., Popov A., Kinoshita K., Ashford A.J., Rybina S.,
RA   Pozniakovsky A., Mayer T.U., Walczak C.E., Karsenti E., Hyman A.A.;
RT   "Control of microtubule dynamics by the antagonistic activities of
RT   XMAP215 and XKCM1 in Xenopus egg extracts.";
RL   Nat. Cell Biol. 2:13-19(2000).
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DR   EMBL; AJ251130; CAB61894.1; -; mRNA.
DR   RefSeq; NP_001090169.1; -.
DR   UniGene; Xl.713; -.
DR   GeneID; 779014; -.
DR   KEGG; xla:779014; -.
DR   CTD; 779014; -.
DR   HOVERGEN; Q9PT63; -.
DR   GO; GO:0005488; F:binding; IEA:InterPro.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR000357; HEAT.
DR   Gene3D; G3DSA:1.25.10.10; ARM-like; 1.
DR   Pfam; PF02985; HEAT; 2.
DR   PROSITE; PS50077; HEAT_REPEAT; 2.
PE   2: Evidence at transcript level;
SQ   SEQUENCE   2065 AA;  228390 MW;  4C879F481E86D5CB CRC64;
     MGDDSEWMKL PIDQKCEHKV WKARLNGYEE AVKLFQKIVD EKSPEWSKYL GLIKRFVTES
     NAVAQLKGLE AALVYVENAH VAGKTTGEVV NGVVNKVFNQ PKARAKELGA DICLMYVEIE
     KAEVVQEELL KGLDNKNPKI VVACVETVRK ALSEFGSKIM TLKPIIKVLP KLFESREKAI
     RDEAKLLAVE IYRWIRDALR PPLQNINPVQ LKELEEEWVK LPQSAPKQTR FLRSQQDLKA
     KFEQQQAAGD DGGDDGEEEI VPQVDAYELL EAVEILSKLP KDFYDKIEAK KWQERKEALE
     AVEALVKNPK IEAGDFADLV KALKTVVGKD TNVMLVALAA KCIAGLAAGL RKKFGSYAGH
     IVPTILEKFK EKKPQVVQAL QEAIDAVFLT TTLQNISEDV LAVMDNKNPA IKQQTSLFLA
     RSFRHCTPST LPKSLLKPFC VALLKQINDS APEVRDAAFE ALGTAQKVVG EKAVNPFLAE
     VDKLKLDRIK ECADKAELAN GKKGGAAAGE KKETKAPAAA PGKPVPNQGA AAEKDAGKAA
     AAPKKAPAAK PGGPVKKAKA PASSGATAKG KKAVENKEII EQELSPEACE ERAAAVLPAS
     CMQQLDSSNW KERLASMEEF QKTVESMERN DIPCQALVKM LAKKPGFKET NFQVMQMKLH
     IVALIAQKGN FSKTSACAVL DGLVDKVGDV KCGGNAKEAL SGIAEACTLP WTAEQVVSLA
     FAQKNPKNQS ETLNWLSNAI KEFGFTGINV KAFISNVKTA LAATNPAIRT SAITLLGVMY
     LYMGAPLRMF FEEEKPALLS QIDAEFEKMK GQTPPVSIRG SKHGSGRDEG EEGEEQDEDA
     PADVTDLLPR TDISDKISSD LVSKIEDKNW KIRKEGLDEV TAIINEAKFI QPSIGELPSA
     LKGRLNDSNK ILVQQTLTIL QQLSTAMGHN IKQHVKNLGM PIITVLGDSK ANVRAAALGT
     LKSWVDQTGM KDWLEGEDLS EELKKENPFL RQELLGWLAE KLPSMRTVPS DLQLCVPYLY
     NCLEDRNGDV RKKAQEALPI FMMHIGFEKM SKATSKLKPA SKDQVVALLE KAKASMPAKP
     AGPPGKASSK QPPAVAQASA SPPPAASSDS GSSTSDYKPD PKKTKPGTQA SKAKTQSVSS
     EGNTSLNPSN TSLTPSKANT SLSKAKPAKQ TLPGKKAPSK PNAKDEEDKS GPIYIIVPNG
     KEQRVKDEKA LKVLKWNFTT PRDEYIEQLK TQMSPCIARW LQDELFHADF QRQIKGLAVM
     TEHLESEKEG VISCLDLVLK WFTLRFFDTN TSVLMKCLEY LKLLFIMLSQ EEYHLTEMEG
     TSFLPYLMLK VGEPKDIVRK DVRAILTKMC QVYPASKMFN FVMEGTKSKN SKQRAECLEE
     LGCLVESYGM NVCQPTPAKA LKEIAIHIGD RDTTVRNAAL NTIVTVYNVH GEQVFKLIGN
     LSEKDMSMLE ERIKRAGKKQ AAAAPAKQVE EKPQRVQSAN ASILRKAPPE DMSSKLNQAR
     NMGGHTEPSH SVPREFQLDL DEIENDNGTV RCEMPALVQH KLDEIFEPVL IPEPKIRAVS
     PHFDDMHSNT ASTINFVISQ VASVDINASI QALAQIDEVL RQEDKAEAMS GHIDQFLIAT
     FMQLRLAYNT HMADERLDKD DIVRLYSCII GNMISLFQME SLAREASTGV LKDLMHGLIS
     LMLDARIEDL EEGQQVVRSV NLLVVKVLEK SDQTNIISAL LMLLQDSLLA TASSPNFSEL
     VMKCLWRMIR LLPEAINNLN LDRILLDIHN FMRVLPKEKL KQHKSEMPMR TLKTLLHTLC
     KLKGPKIMDH LSMIENKHES ELEAHLLRVM KHSIDRTGSK GDKETEKGAS CIEDKVGKAN
     VSDFLAEMFK KIGSKENTKE GLAELYEYKK KYSDADIKPF LKNSSQFFQS YVERGLRLIE
     MEREGKARIA PNTGMSTHVT EMTPLPTVTN TAAPVSNTNG EEVGPSVYLE RLKILRQRCG
     LDNAKQDERP PLTSLLSKSS APAVVSSTDM LHSKLSQLRE SREQFQHVEL DSNQTYPSTT
     TSSSASSTNI DDLKKRLERI KSSRK
//