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Protein
Submitted name:

Cation channel TRP-1

Gene

trpc1

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Ion channelSAAS annotation, ReceptorImported

Keywords - Biological processi

Ion transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Cation channel TRP-1Imported
Submitted name:
Transient receptor potential proteinImported
Gene namesi
Name:trpc1Imported
Synonyms:trp1Imported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-1004981. trpc1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei336 – 35621HelicalSequence analysisAdd
BLAST
Transmembranei372 – 39221HelicalSequence analysisAdd
BLAST
Transmembranei522 – 54423HelicalSequence analysisAdd
BLAST
Transmembranei579 – 59820HelicalSequence analysisAdd
BLAST
Transmembranei604 – 62724HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini38 – 11881ANK_REP_REGIONInterPro annotationAdd
BLAST
Domaini178 – 24063TRP_2InterPro annotationAdd
BLAST
Domaini379 – 641263Ion_transInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the transient receptor (TC 1.A.4) family. [View classification]SAAS annotation

Keywords - Domaini

ANK repeatSAAS annotation, RepeatSAAS annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOVERGENiHBG068337.
KOiK04964.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR005821. Ion_trans_dom.
IPR004729. TRP_channel.
IPR013555. TRP_dom.
IPR005457. TRPC1_channel.
IPR002153. TRPC_channel.
[Graphical view]
PANTHERiPTHR10117. PTHR10117. 1 hit.
PfamiPF12796. Ank_2. 1 hit.
PF00520. Ion_trans. 1 hit.
PF08344. TRP_2. 1 hit.
[Graphical view]
PRINTSiPR01097. TRNSRECEPTRP.
PR01642. TRPCHANNEL1.
SMARTiSM00248. ANK. 3 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
TIGRFAMsiTIGR00870. trp. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9PRI8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAALYQSTDS SSPNTFLALK DVREVKEETT LDERLFLLAC EKGDYYMVKK
60 70 80 90 100
LLEENSSEEL NINSLDILGR NAITISIENE NLDILQLLLN YGFQSTDALL
110 120 130 140 150
VAIDSEVVGA VDILLNHQPK WTTRPSIVKL MEQIQNPEYS TTMDVAPVIL
160 170 180 190 200
AAHRNNYEIL TMLLKQDVSL PKPHAVGCEC TLCTAKNKKD SLRHSRFRLD
210 220 230 240 250
IYRCLASPAL IMLTEEDPIL RAFELSADLK ELSLVEVEFR NDYEELAQKC
260 270 280 290 300
KTFAKDLLAQ ARNSRELEVI LNHQSSDEPL DKRGLLEERM NLSRLKLAIK
310 320 330 340 350
YNQKEFVSQS NCQQFLNTVW FGQMAAYRRK HTCKKILIVL TVGIFWPVLS
360 370 380 390 400
MCYLLAPKSQ VGRIIHTPFM KFIIHGASYF TFLLLLNLYS LVYNEDEKNT
410 420 430 440 450
MGPALERIDF LLIIWLIGMV WSDVKQLWYD GLEDFLKESQ NQLSFVMNSL
460 470 480 490 500
YLATFALKVV AHNKFHSIAE RKDWDAFHPT LVVEGLFAFG NVLSYLRLFF
510 520 530 540 550
MYTTSSILGP LQIFMGQMLQ DFGKFLGMFL LVLFSFTIGL THLYEKGYTT
560 570 580 590 600
NEQKDCVGIF CEQQSNNTFH SFTGTCYALF WYIFSLAHVT LFVTRFNFSE
610 620 630 640 650
ELQSIVGALI VGTYNVVVVI VLTKLLVAML HKSFQLIANH EDKEWKFARA
660 670 680 690 700
KLWLSYFDDK CTLPPPFNIV PSPKTICYLF NSISKWICSH TTSGRVKRQN
710 720 730 740 750
SFKEWKSLRQ KRDENYQKVM CCLVHRYLTS MRQKMQSTDQ ATVENLNELC
760 770
QDLSKFRNEM RDLLGFRTSK YAMFYPRN
Length:778
Mass (Da):90,034
Last modified:May 1, 2000 - v1
Checksum:i50F14A06EAB78E2A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF127031 mRNA. Translation: AAD22978.1.
AF113508 mRNA. Translation: AAD26639.1.
RefSeqiNP_001083819.1. NM_001090350.1.
UniGeneiXl.470.

Genome annotation databases

GeneIDi399136.
KEGGixla:399136.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF127031 mRNA. Translation: AAD22978.1.
AF113508 mRNA. Translation: AAD26639.1.
RefSeqiNP_001083819.1. NM_001090350.1.
UniGeneiXl.470.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi399136.
KEGGixla:399136.

Organism-specific databases

CTDi7220.
XenbaseiXB-GENE-1004981. trpc1.

Phylogenomic databases

HOVERGENiHBG068337.
KOiK04964.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR005821. Ion_trans_dom.
IPR004729. TRP_channel.
IPR013555. TRP_dom.
IPR005457. TRPC1_channel.
IPR002153. TRPC_channel.
[Graphical view]
PANTHERiPTHR10117. PTHR10117. 1 hit.
PfamiPF12796. Ank_2. 1 hit.
PF00520. Ion_trans. 1 hit.
PF08344. TRP_2. 1 hit.
[Graphical view]
PRINTSiPR01097. TRNSRECEPTRP.
PR01642. TRPCHANNEL1.
SMARTiSM00248. ANK. 3 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
TIGRFAMsiTIGR00870. trp. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ9PRI8_XENLA
AccessioniPrimary (citable) accession number: Q9PRI8
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: September 7, 2016
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.