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Protein

Guanylate kinase

Gene

gmk

Organism
Ureaplasma parvum serovar 3 (strain ATCC 700970)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.By similarity

Catalytic activityi

ATP + GMP = ADP + GDP.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi11 – 18ATPBy similarity8

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinase (EC:2.7.4.8)
Alternative name(s):
GMP kinase
Gene namesi
Name:gmk
Ordered Locus Names:UU213
OrganismiUreaplasma parvum serovar 3 (strain ATCC 700970)
Taxonomic identifieri273119 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeUreaplasma
Proteomesi
  • UP000000423 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001706351 – 191Guanylate kinaseAdd BLAST191

Interactioni

Protein-protein interaction databases

STRINGi273119.UU213.

Structurei

3D structure databases

ProteinModelPortaliQ9PQS9.
SMRiQ9PQS9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 185Guanylate kinase-likeAdd BLAST182

Sequence similaritiesi

Belongs to the guanylate kinase family.Curated

Phylogenomic databases

eggNOGiENOG4108UHA. Bacteria.
COG0194. LUCA.
HOGENOMiHOG000037639.
KOiK00942.
OMAiAGNYYGT.

Family and domain databases

HAMAPiMF_00328. Guanylate_kinase. 1 hit.
InterProiView protein in InterPro
IPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like_dom.
IPR017665. Guanylate_kinase.
IPR020590. Guanylate_kinase_CS.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00625. Guanylate_kin. 1 hit.
SMARTiView protein in SMART
SM00072. GuKc. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR03263. guanyl_kin. 1 hit.
PROSITEiView protein in PROSITE
PS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9PQS9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKRGKLIVFS GPSGVGKHTI LSKIINRKDL NLAYSISMTT RKKREGEVNG
60 70 80 90 100
VDYYFVNDEE FKKAILNNEL IEWAEFVGNK YGTPRTIVEK LRDEGKNVIL
110 120 130 140 150
EIEVVGALKV LDLYKNDDLI SIFLLPPSID ELKKRLLKRN TETLETIKKR
160 170 180 190
IQKATHEITI KDYYQYNIIN DNPDHAANQL AEIILNEIKQ S
Length:191
Mass (Da):22,005
Last modified:October 1, 2000 - v1
Checksum:i8E552F2E9AF19E9F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF222894 Genomic DNA. Translation: AAF30621.1.
RefSeqiWP_006688865.1. NC_002162.1.

Genome annotation databases

EnsemblBacteriaiAAF30621; AAF30621; UU213.
GeneIDi29672624.
KEGGiuur:UU213.

Similar proteinsi

Entry informationi

Entry nameiKGUA_UREPA
AccessioniPrimary (citable) accession number: Q9PQS9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: October 1, 2000
Last modified: March 28, 2018
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome