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Q9PQL3 (SYR_UREPA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:UU278
OrganismUreaplasma parvum serovar 3 (strain ATCC 700970) [Complete proteome] [HAMAP]
Taxonomic identifier273119 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesMycoplasmataceaeUreaplasma

Protein attributes

Sequence length550 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 550550Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000151631

Regions

Motif123 – 13311"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q9PQL3 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 0400D6105A17A69B

FASTA55063,662
        10         20         30         40         50         60 
MITQKISEEL NKALAKMGIH DTQETKILVD KTKNIKFGDF YTNIAMILSK KNNKSSLEIA 

        70         80         90        100        110        120 
KEIANNFEQD LFLEVNLQPP GFLNFKLKAK DHENLLKQIY YEKDRFGQFS KKNITYNIEY 

       130        140        150        160        170        180 
VSANPTGYLH IAHAANAIYG DILANLLKIY GYDVETEYWI NDAGNQIDKL AMSVLVRYLQ 

       190        200        210        220        230        240 
LQNINIQLPA DAYHGQEIHL VAQTLYQTYK NQFINVRLNE KYEIDDDIAN QEIKNFAVKY 

       250        260        270        280        290        300 
LLNEIKNDLA SINTFIDTYT SENWIRNSGR ILEVLSKIKP YTYTLDGALW LKTTTFGDDK 

       310        320        330        340        350        360 
DRVLIKSDGS YTYFTPDIAY HDYKFNKTNT TKLIDVWGTD HLGYIARLKA AMNALGYDPN 

       370        380        390        400        410        420 
NLEIVCAQVM KLVKNNQEFK LSKRSGQSLT IKDLVEIIGK DALRWFLGSS SMNSHVIIDV 

       430        440        450        460        470        480 
DIALSKNNNN PLYYVQYAHA RANQVLNKQV YELDFKTDLL TETRERELLN QLHFYKQTIA 

       490        500        510        520        530        540 
NAANNREPHR ISNYLYDLAQ IFHNYYANVK INNDNNKVLS AQRYTLVWCV KQVLANGLAI 

       550 
MKITPYDQMY 

« Hide

References

[1]"The complete sequence of the mucosal pathogen Ureaplasma urealyticum."
Glass J.I., Lefkowitz E.J., Glass J.S., Heiner C.R., Chen E.Y., Cassell G.H.
Nature 407:757-762(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700970.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF222894 Genomic DNA. Translation: AAF30687.1.
RefSeqNP_078112.1. NC_002162.1.

3D structure databases

ProteinModelPortalQ9PQL3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING273119.UU278.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAF30687; AAF30687; UU278.
GeneID876142.
KEGGuur:UU278.
PATRIC20534106. VBIUrePar45146_0288.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMARFIMLTR.
OrthoDBEOG6JB13C.
ProtClustDBPRK01611.

Enzyme and pathway databases

BioCycUPAR273119:GHVP-287-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
ProtoNetSearch...

Entry information

Entry nameSYR_UREPA
AccessionPrimary (citable) accession number: Q9PQL3
Entry history
Integrated into UniProtKB/Swiss-Prot: November 7, 2003
Last sequence update: October 1, 2000
Last modified: April 16, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries