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Q9PQL2 (PGK_UREPA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:pgk
Ordered Locus Names:UU279
OrganismUreaplasma parvum serovar 3 (strain ATCC 700970) [Complete proteome] [HAMAP]
Taxonomic identifier273119 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesMycoplasmataceaeUreaplasma

Protein attributes

Sequence length422 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5.

Subunit structure

Monomer By similarity.

Subcellular location

Cytoplasm Potential.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 422422Phosphoglycerate kinase
PRO_0000146033

Regions

Nucleotide binding370 – 3734ATP By similarity
Region24 – 263Substrate binding By similarity
Region64 – 674Substrate binding By similarity

Sites

Binding site1291Substrate By similarity
Binding site1711Substrate By similarity
Binding site2221ATP By similarity
Binding site3091ATP; via carbonyl oxygen By similarity
Binding site3401ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9PQL2 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: F3F45A1542A3783C

FASTA42247,383
        10         20         30         40         50         60 
MNSLNKKSIK DLDVNGKTIV LHLDLNVVVD YENKRILNDR KLRASLPTIN YLINHNAKIV 

        70         80         90        100        110        120 
ILSHLGRIKT LADKQSGKYS LEIIVDELRN RVSKNVNRVV FSPLNYGETV VQMVNDLEER 

       130        140        150        160        170        180 
DILILENTRY CDISDEGEYV GLEWDGSEIL GQFWGMLGDI FIDDAYGVAH RQLSSNYQTA 

       190        200        210        220        230        240 
KFAKKSALGF LIVNEINHLD IALEVPKSPY LALIGGNRVA DKIAAIEVLC ERADQVIIGG 

       250        260        270        280        290        300 
GLVYTFLYAQ GYNVGLNLVE RNMIDDCNNI LEKYGKKILI CFDFLCNNDF SDTRPIYRKI 

       310        320        330        340        350        360 
DEGLEGLYGL DIGKRSLKFI KHEIYRSKTI LLNGPFGVIE NIKNYAQGTT EICKSMAKQT 

       370        380        390        400        410        420 
TRGAYTIICD IDTSSHAEYL GLDKYINFIS TGGGASLSYI EEGVLDGLET IDNVPLNVLK 


KE 

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References

[1]"The complete sequence of the mucosal pathogen Ureaplasma urealyticum."
Glass J.I., Lefkowitz E.J., Glass J.S., Heiner C.R., Chen E.Y., Cassell G.H.
Nature 407:757-762(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700970.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF222894 Genomic DNA. Translation: AAF30688.1.
RefSeqNP_078113.1. NC_002162.1.

3D structure databases

ProteinModelPortalQ9PQL2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING273119.UU279.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAF30688; AAF30688; UU279.
GeneID876401.
KEGGuur:UU279.
PATRIC20534108. VBIUrePar45146_0289.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0126.
HOGENOMHOG000227108.
KOK00927.
OMADMIFDIG.
OrthoDBEOG64N9Z0.
ProtClustDBPRK00073.

Enzyme and pathway databases

BioCycUPAR273119:GHVP-288-MONOMER.
UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
ProtoNetSearch...

Entry information

Entry namePGK_UREPA
AccessionPrimary (citable) accession number: Q9PQL2
Entry history
Integrated into UniProtKB/Swiss-Prot: July 5, 2004
Last sequence update: October 1, 2000
Last modified: February 19, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways