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Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Ureaplasma parvum serovar 3 (strain ATCC 700970)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate.
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Phosphoglycerate kinase (pgk)
  3. 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (gpmI)
  4. Enolase (eno)
  5. Pyruvate kinase (pyk)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei129SubstrateBy similarity1
Binding sitei171SubstrateBy similarity1
Binding sitei222ATPBy similarity1
Binding sitei309ATP; via carbonyl oxygenBy similarity1
Binding sitei340ATPBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi370 – 373ATPBy similarity4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
Biological processGlycolysis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00109; UER00185

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase (EC:2.7.2.3)
Gene namesi
Name:pgk
Ordered Locus Names:UU279
OrganismiUreaplasma parvum serovar 3 (strain ATCC 700970)
Taxonomic identifieri273119 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeUreaplasma
Proteomesi
  • UP000000423 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001460331 – 422Phosphoglycerate kinaseAdd BLAST422

Proteomic databases

PRIDEiQ9PQL2

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

STRINGi273119.UU279

Structurei

3D structure databases

ProteinModelPortaliQ9PQL2
SMRiQ9PQL2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni24 – 26Substrate bindingBy similarity3
Regioni64 – 67Substrate bindingBy similarity4

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.Curated

Phylogenomic databases

eggNOGiENOG4105BZA Bacteria
COG0126 LUCA
HOGENOMiHOG000227108
KOiK00927
OMAiDMIFDIG

Family and domain databases

Gene3Di3.40.50.1260, 3 hits
InterProiView protein in InterPro
IPR001576 Phosphoglycerate_kinase
IPR015824 Phosphoglycerate_kinase_N
IPR036043 Phosphoglycerate_kinase_sf
PANTHERiPTHR11406 PTHR11406, 1 hit
PfamiView protein in Pfam
PF00162 PGK, 1 hit
PIRSFiPIRSF000724 Pgk, 1 hit
PRINTSiPR00477 PHGLYCKINASE
SUPFAMiSSF53748 SSF53748, 1 hit

Sequencei

Sequence statusi: Complete.

Q9PQL2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSLNKKSIK DLDVNGKTIV LHLDLNVVVD YENKRILNDR KLRASLPTIN
60 70 80 90 100
YLINHNAKIV ILSHLGRIKT LADKQSGKYS LEIIVDELRN RVSKNVNRVV
110 120 130 140 150
FSPLNYGETV VQMVNDLEER DILILENTRY CDISDEGEYV GLEWDGSEIL
160 170 180 190 200
GQFWGMLGDI FIDDAYGVAH RQLSSNYQTA KFAKKSALGF LIVNEINHLD
210 220 230 240 250
IALEVPKSPY LALIGGNRVA DKIAAIEVLC ERADQVIIGG GLVYTFLYAQ
260 270 280 290 300
GYNVGLNLVE RNMIDDCNNI LEKYGKKILI CFDFLCNNDF SDTRPIYRKI
310 320 330 340 350
DEGLEGLYGL DIGKRSLKFI KHEIYRSKTI LLNGPFGVIE NIKNYAQGTT
360 370 380 390 400
EICKSMAKQT TRGAYTIICD IDTSSHAEYL GLDKYINFIS TGGGASLSYI
410 420
EEGVLDGLET IDNVPLNVLK KE
Length:422
Mass (Da):47,383
Last modified:October 1, 2000 - v1
Checksum:iF3F45A1542A3783C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF222894 Genomic DNA Translation: AAF30688.1
RefSeqiWP_006688945.1, NC_002162.1

Genome annotation databases

EnsemblBacteriaiAAF30688; AAF30688; UU279
GeneIDi29672564
KEGGiuur:UU279

Similar proteinsi

Entry informationi

Entry nameiPGK_UREPA
AccessioniPrimary (citable) accession number: Q9PQL2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 5, 2004
Last sequence update: October 1, 2000
Last modified: May 23, 2018
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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