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Q9PPN6

- RNPA_UREPA

UniProt

Q9PPN6 - RNPA_UREPA

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Protein

Ribonuclease P protein component

Gene

rnpA

Organism
Ureaplasma parvum serovar 3 (strain ATCC 700970)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

GO - Molecular functioni

  1. ribonuclease P activity Source: UniProtKB-EC
  2. tRNA binding Source: InterPro

GO - Biological processi

  1. tRNA processing Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Hydrolase, Nuclease

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

RNA-binding

Enzyme and pathway databases

BioCyciUPAR273119:GHVP-644-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein componentUniRule annotation (EC:3.1.26.5UniRule annotation)
Short name:
RNase P proteinUniRule annotation
Short name:
RNaseP proteinUniRule annotation
Alternative name(s):
Protein C5UniRule annotation
Gene namesi
Name:rnpAUniRule annotation
Ordered Locus Names:UU603
OrganismiUreaplasma parvum serovar 3 (strain ATCC 700970)
Taxonomic identifieri273119 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeUreaplasma
ProteomesiUP000000423: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 113113Ribonuclease P protein componentPRO_0000198561Add
BLAST

Interactioni

Subunit structurei

Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.UniRule annotation

Protein-protein interaction databases

STRINGi273119.UU603.

Structurei

3D structure databases

ProteinModelPortaliQ9PPN6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RnpA family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0594.
HOGENOMiHOG000052712.
KOiK03536.
OrthoDBiEOG654P5P.

Family and domain databases

Gene3Di3.30.230.10. 1 hit.
HAMAPiMF_00227. RNase_P.
InterProiIPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR000100. RNase_P.
IPR020539. RNase_P_CS.
[Graphical view]
PfamiPF00825. Ribonuclease_P. 1 hit.
[Graphical view]
ProDomiPD003629. Ribonuclease_P. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF54211. SSF54211. 1 hit.
TIGRFAMsiTIGR00188. rnpA. 1 hit.
PROSITEiPS00648. RIBONUCLEASE_P. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9PPN6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MANFISLKKN EDILDTIKKQ QKIHSNQIVV YFRKTNLKNV RLAISISKKK
60 70 80 90 100
FKLATQRNRI RRLIKAWFIA ADIPIKSYDI VVLVKPSFID GSFVLNCNNL
110
KIILQRIINK EKR
Length:113
Mass (Da):13,282
Last modified:December 1, 2000 - v1
Checksum:i8804D398B4CDE812
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF222894 Genomic DNA. Translation: AAF31017.1.
RefSeqiNP_078442.1. NC_002162.1.

Genome annotation databases

EnsemblBacteriaiAAF31017; AAF31017; UU603.
GeneIDi876089.
KEGGiuur:UU603.
PATRICi20534843. VBIUrePar45146_0626.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF222894 Genomic DNA. Translation: AAF31017.1 .
RefSeqi NP_078442.1. NC_002162.1.

3D structure databases

ProteinModelPortali Q9PPN6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 273119.UU603.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAF31017 ; AAF31017 ; UU603 .
GeneIDi 876089.
KEGGi uur:UU603.
PATRICi 20534843. VBIUrePar45146_0626.

Phylogenomic databases

eggNOGi COG0594.
HOGENOMi HOG000052712.
KOi K03536.
OrthoDBi EOG654P5P.

Enzyme and pathway databases

BioCyci UPAR273119:GHVP-644-MONOMER.

Family and domain databases

Gene3Di 3.30.230.10. 1 hit.
HAMAPi MF_00227. RNase_P.
InterProi IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR000100. RNase_P.
IPR020539. RNase_P_CS.
[Graphical view ]
Pfami PF00825. Ribonuclease_P. 1 hit.
[Graphical view ]
ProDomi PD003629. Ribonuclease_P. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
SUPFAMi SSF54211. SSF54211. 1 hit.
TIGRFAMsi TIGR00188. rnpA. 1 hit.
PROSITEi PS00648. RIBONUCLEASE_P. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The complete sequence of the mucosal pathogen Ureaplasma urealyticum."
    Glass J.I., Lefkowitz E.J., Glass J.S., Heiner C.R., Chen E.Y., Cassell G.H.
    Nature 407:757-762(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700970.

Entry informationi

Entry nameiRNPA_UREPA
AccessioniPrimary (citable) accession number: Q9PPN6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: October 1, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3