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Q9PPK3 (SYGA_CAMJE) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glycine--tRNA ligase alpha subunit
EC=6.1.1.14
Alternative name(s):
Glycyl-tRNA synthetase alpha subunit
Short name=GlyRS
Gene names
Name:glyQ
Ordered Locus Names:Cj0704
OrganismCampylobacter jejuni
Taxonomic identifier197 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length287 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP MF_00254

Subunit structure

Tetramer of two alpha and two beta subunits By similarity.

Subcellular location

Cytoplasm HAMAP MF_00254.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Biological processglycyl-tRNA aminoacylation

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

glycine-tRNA ligase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 287287Glycine--tRNA ligase alpha subunit HAMAP MF_00254
PRO_0000072833

Secondary structure

1 .................................... 287
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q9PPK3 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 3ED6803DD5B72908

FASTA28733,058
        10         20         30         40         50         60 
MTFSQMILNL QNYWQEQGCA IMQPYDMPAG AGTFHPATFL RSLGKKPWAA AYVAPSRRPT 

        70         80         90        100        110        120 
DGRYGENPNR LGAYYQFQVL IKPSPDNIQE LYLKSLENLG FDLKSHDIRF VEDNWESPSL 

       130        140        150        160        170        180 
GAWGLGWEVW LDGMEVTQFT YFQQVGGIAV DLVSAEITYG LERIAMYLQN VDNVYDIVWS 

       190        200        210        220        230        240 
EFNGEKIKYA DVHKQSEYEF SKYNFEVSDV KILNEQFENS YKECKNILEQ GLALPAYDYC 

       250        260        270        280 
MLAAHTFNLL DARGAISVAQ RQDYMLKIRE LSKNCAEIYK KNLNEAE

« Hide

References

[1]"The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences."
Parkhill J., Wren B.W., Mungall K.L., Ketley J.M., Churcher C.M., Basham D., Chillingworth T., Davies R.M., Feltwell T., Holroyd S., Jagels K., Karlyshev A.V., Moule S., Pallen M.J., Penn C.W., Quail M.A., Rajandream M.A., Rutherford K.M. expand/collapse author list , van Vliet A.H.M., Whitehead S., Barrell B.G.
Nature 403:665-668(2000) [PubMed: 10688204] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NCTC 11168 / Serotype O:2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AL111168 Genomic DNA. Translation: CAL34841.1.
PIRC81341.
RefSeqYP_002344122.1. NC_002163.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3RGLX-ray2.45A/B1-287[»]
3UFGX-ray2.55A/B1-287[»]
ProteinModelPortalQ9PPK3.
SMRQ9PPK3. Positions 1-279.
ModBaseSearch...

Protein-protein interaction databases

IntActQ9PPK3. 4 interactions.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID905023.
GenomeReviewsGene locus Cj0704 in contig AL111168_GR.
KEGGcje:Cj0704.
PATRIC20058354. VBICamJej33762_0696.

Phylogenomic databases

HOGENOMHBG285316.
OMACRRPTDG.
ProtClustDBPRK09348.

Enzyme and pathway databases

BioCycCJEJ192222:CJ0704-MONOMER.

Family and domain databases

HAMAPMF_00254. Gly_tRNA_synth_alpha.
[Tree]
InterProIPR006194. Gly-tRNA-synth_II_heterodimer.
IPR002310. Gly-tRNA_synth_IIc_asu.
[Graphical view]
KOK01878.
PfamPF02091. tRNA-synt_2e. 1 hit.
[Graphical view]
PRINTSPR01044. TRNASYNTHGA.
TIGRFAMsTIGR00388. GlyQ. 1 hit.
PROSITEPS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYGA_CAMJE
AccessionPrimary (citable) accession number: Q9PPK3
Secondary accession number(s): Q0PAH5
Entry history
Integrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: October 1, 2000
Last modified: January 25, 2012
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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