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Q9PP76 (PSD_CAMJE) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphatidylserine decarboxylase proenzyme
EC=4.1.1.65

Cleaved into the following 2 chains:

  1. Phosphatidylserine decarboxylase alpha chain
  2. Phosphatidylserine decarboxylase beta chain
Gene names
Name:psd
Ordered Locus Names:Cj0847
OrganismCampylobacter jejuni
Taxonomic identifier197 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length266 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00662

Cofactor

Pyruvoyl group By similarity. HAMAP MF_00662

Pathway

Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00662

Sequence similarities

Belongs to the phosphatidylserine decarboxylase family. Type 1 subfamily.

Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   PTMZymogen
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processphospholipid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionphosphatidylserine decarboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 236236Phosphatidylserine decarboxylase beta chain By similarity
PRO_0000029639
Chain237 – 26630Phosphatidylserine decarboxylase alpha chain By similarity
PRO_0000029640

Sites

Site236 – 2372Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue2371Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9PP76 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 699FF37AF598B973

FASTA26630,516
        10         20         30         40         50         60 
MSFSKESSRL FGFVAGIKFP KMIQKVINEN YVKYFNINMS EFKAPCEYES LNALFTRTLQ 

        70         80         90        100        110        120 
IPRKFEEGFI SPSDGKILEC GSTFLANEEH FAFSIKGHAY SVEELLKDSF EKDELKNGLD 

       130        140        150        160        170        180 
YVNIYLSPKD YHRYHSPCDM QILSATYTSG VLYSVNEKHL ERISNLYVKN ERVSLKCQNE 

       190        200        210        220        230        240 
KGIFWLVFVG AQNVGKMRFN FDASIQTNAK ISHNFTRKYE NLNFKKGEEL GNFELGSTIV 

       250        260 
LISQKGLLTF NLKVGQGIKF GEKIAD

« Hide

References

[1]"The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences."
Parkhill J., Wren B.W., Mungall K.L., Ketley J.M., Churcher C.M., Basham D., Chillingworth T., Davies R.M., Feltwell T., Holroyd S., Jagels K., Karlyshev A.V., Moule S., Pallen M.J., Penn C.W., Quail M.A., Rajandream M.A., Rutherford K.M. expand/collapse author list , van Vliet A.H.M., Whitehead S., Barrell B.G.
Nature 403:665-668(2000) [PubMed: 10688204] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NCTC 11168 / Serotype O:2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AL111168 Genomic DNA. Translation: CAL34975.1.
PIRG81357.
RefSeqYP_002344254.1. NC_002163.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

IntActQ9PP76. 2 interactions.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID904800.
GenomeReviewsGene locus Cj0847 in contig AL111168_GR.
KEGGcje:Cj0847.
PATRIC20058642. VBICamJej33762_0835.

Phylogenomic databases

HOGENOMHBG302256.
OMAMCQSEAR.
ProtClustDBPRK03934.

Enzyme and pathway databases

BioCycCJEJ192222:CJ0847-MONOMER.

Family and domain databases

HAMAPMF_00662. PS_decarb_type1.
[Tree]
InterProIPR003817. PS_Dcarbxylase.
IPR005221. PS_decarb.
[Graphical view]
KOK01613.
PANTHERPTHR10067. PS_decarb. 1 hit.
PfamPF02666. PS_Dcarbxylase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00163. PS_decarb. 1 hit.
ProtoNetSearch...

Entry information

Entry namePSD_CAMJE
AccessionPrimary (citable) accession number: Q9PP76
Secondary accession number(s): Q0PA43
Entry history
Integrated into UniProtKB/Swiss-Prot: July 3, 2003
Last sequence update: October 1, 2000
Last modified: January 25, 2012
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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