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Q9PP06

- APT_CAMJE

UniProt

Q9PP06 - APT_CAMJE

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Protein
Adenine phosphoribosyltransferase
Gene
apt, Cj0927
Organism
Campylobacter jejuni subsp. jejuni serotype O:2 (strain NCTC 11168)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis By similarity.UniRule annotation

Catalytic activityi

AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. adenine phosphoribosyltransferase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. AMP salvage Source: UniProtKB-UniPathway
  2. adenine salvage Source: InterPro
  3. purine ribonucleoside salvage Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Purine salvage

Enzyme and pathway databases

BioCyciCJEJ192222:GJTS-895-MONOMER.
UniPathwayiUPA00588; UER00646.

Names & Taxonomyi

Protein namesi
Recommended name:
Adenine phosphoribosyltransferase (EC:2.4.2.7)
Short name:
APRT
Gene namesi
Name:apt
Ordered Locus Names:Cj0927
OrganismiCampylobacter jejuni subsp. jejuni serotype O:2 (strain NCTC 11168)
Taxonomic identifieri192222 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter
ProteomesiUP000000799: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 182182Adenine phosphoribosyltransferaseUniRule annotation
PRO_0000149368Add
BLAST

Interactioni

Subunit structurei

Homodimer By similarity.UniRule annotation

Protein-protein interaction databases

IntActiQ9PP06. 13 interactions.
STRINGi192222.Cj0927.

Structurei

3D structure databases

ProteinModelPortaliQ9PP06.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0503.
HOGENOMiHOG000036776.
KOiK00759.
OMAiAGIMFRD.
OrthoDBiEOG6T4S55.

Family and domain databases

Gene3Di3.40.50.2020. 1 hit.
HAMAPiMF_00004. Aden_phosphoribosyltr.
InterProiIPR005764. Ade_phspho_trans.
IPR000836. PRibTrfase_dom.
IPR029057. PRTase-like.
[Graphical view]
PfamiPF00156. Pribosyltran. 1 hit.
[Graphical view]
SUPFAMiSSF53271. SSF53271. 1 hit.
TIGRFAMsiTIGR01090. apt. 1 hit.
PROSITEiPS00103. PUR_PYR_PR_TRANSFER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9PP06-1 [UniParc]FASTAAdd to Basket

« Hide

MIKLTQEEQK YLLDSIRIIP DFPKKGIIFR DITTLLNNKE ALNFLLKHLK    50
ERYKDYNLDF IAGTESRGFI FASMICAKLN LPFVPIRKPG KLPFETFSCE 100
YDLEYGSDKV ELHKDAFKNI QNARVLLVDD LIATGGTAIA SYELIQKAGA 150
KCVEACFLIN LKDLNGANKL EKLTSVYSVL EI 182
Length:182
Mass (Da):20,671
Last modified:October 1, 2000 - v1
Checksum:i96C575308263D94A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL111168 Genomic DNA. Translation: CAL35047.1.
PIRiF81366.
RefSeqiYP_002344325.1. NC_002163.1.

Genome annotation databases

EnsemblBacteriaiCAL35047; CAL35047; Cj0927.
GeneIDi905205.
KEGGicje:Cj0927.
PATRICi20058798. VBICamJej33762_0911.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL111168 Genomic DNA. Translation: CAL35047.1 .
PIRi F81366.
RefSeqi YP_002344325.1. NC_002163.1.

3D structure databases

ProteinModelPortali Q9PP06.
ModBasei Search...

Protein-protein interaction databases

IntActi Q9PP06. 13 interactions.
STRINGi 192222.Cj0927.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAL35047 ; CAL35047 ; Cj0927 .
GeneIDi 905205.
KEGGi cje:Cj0927.
PATRICi 20058798. VBICamJej33762_0911.

Phylogenomic databases

eggNOGi COG0503.
HOGENOMi HOG000036776.
KOi K00759.
OMAi AGIMFRD.
OrthoDBi EOG6T4S55.

Enzyme and pathway databases

UniPathwayi UPA00588 ; UER00646 .
BioCyci CJEJ192222:GJTS-895-MONOMER.

Family and domain databases

Gene3Di 3.40.50.2020. 1 hit.
HAMAPi MF_00004. Aden_phosphoribosyltr.
InterProi IPR005764. Ade_phspho_trans.
IPR000836. PRibTrfase_dom.
IPR029057. PRTase-like.
[Graphical view ]
Pfami PF00156. Pribosyltran. 1 hit.
[Graphical view ]
SUPFAMi SSF53271. SSF53271. 1 hit.
TIGRFAMsi TIGR01090. apt. 1 hit.
PROSITEi PS00103. PUR_PYR_PR_TRANSFER. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NCTC 11168.

Entry informationi

Entry nameiAPT_CAMJE
AccessioniPrimary (citable) accession number: Q9PP06
Secondary accession number(s): Q0P9X2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 25, 2002
Last sequence update: October 1, 2000
Last modified: June 11, 2014
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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