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Protein

Deoxycytidine triphosphate deaminase

Gene

dcd

Organism
Campylobacter jejuni subsp. jejuni serotype O:2 (strain NCTC 11168)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

dCTP + H2O = dUTP + NH3.UniRule annotation

Pathway: dUMP biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes dUMP from dCTP (dUTP route).UniRule annotation
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. Deoxycytidine triphosphate deaminase (dcd)
  2. no protein annotated in this organism
This subpathway is part of the pathway dUMP biosynthesis, which is itself part of Pyrimidine metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes dUMP from dCTP (dUTP route), the pathway dUMP biosynthesis and in Pyrimidine metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Nucleotide metabolism

Enzyme and pathway databases

BioCyciCJEJ192222:GJTS-1265-MONOMER.
UniPathwayiUPA00610; UER00665.

Names & Taxonomyi

Protein namesi
Recommended name:
Deoxycytidine triphosphate deaminaseUniRule annotation (EC:3.5.4.13UniRule annotation)
Short name:
dCTP deaminaseUniRule annotation
Gene namesi
Name:dcdUniRule annotation
Ordered Locus Names:Cj1292
OrganismiCampylobacter jejuni subsp. jejuni serotype O:2 (strain NCTC 11168)
Taxonomic identifieri192222 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter
ProteomesiUP000000799 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 186186Deoxycytidine triphosphate deaminasePRO_0000155972Add
BLAST

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
Cj1374cQ9PMS63EBI-1271615,EBI-1271444

Protein-protein interaction databases

IntActiQ9PN07. 18 interactions.
STRINGi192222.Cj1292.

Structurei

3D structure databases

ProteinModelPortaliQ9PN07.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the dCTP deaminase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0717.
HOGENOMiHOG000228600.
KOiK01494.
OMAiMEYFRIP.
OrthoDBiEOG67DPKR.

Family and domain databases

Gene3Di2.70.40.10. 1 hit.
HAMAPiMF_00146. dCTP_deaminase.
InterProiIPR011962. dCTP_deam.
IPR029054. dUTPase-like.
IPR008180. dUTPase/dCTP_deaminase.
[Graphical view]
PfamiPF00692. dUTPase. 1 hit.
[Graphical view]
SUPFAMiSSF51283. SSF51283. 1 hit.
TIGRFAMsiTIGR02274. dCTP_deam. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9PN07-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLKADNWIR KMALEHKMIE PFCEANIGKG VVSYGLSSYG YDIRVGREFK
60 70 80 90 100
IFTNVNSTVV DPKNFVEENV VDFEGDVCIV PANSFALART IEYFKMPDNV
110 120 130 140 150
LAICLGKSTY ARCGIIVNVT PFEPGFEGHI TIEISNTTPL PAKIYANEGI
160 170 180
AQVLFLQGDE KCDTTYKDKK GKYQAQTGIT LPRILK
Length:186
Mass (Da):20,699
Last modified:October 1, 2000 - v1
Checksum:i68DC660FB28FD33C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL111168 Genomic DNA. Translation: CAL35406.1.
PIRiA81272.
RefSeqiWP_002854086.1. NC_002163.1.
YP_002344682.1. NC_002163.1.

Genome annotation databases

EnsemblBacteriaiCAL35406; CAL35406; Cj1292.
GeneIDi905584.
KEGGicje:Cj1292.
PATRICi20059548. VBICamJej33762_1274.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL111168 Genomic DNA. Translation: CAL35406.1.
PIRiA81272.
RefSeqiWP_002854086.1. NC_002163.1.
YP_002344682.1. NC_002163.1.

3D structure databases

ProteinModelPortaliQ9PN07.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9PN07. 18 interactions.
STRINGi192222.Cj1292.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAL35406; CAL35406; Cj1292.
GeneIDi905584.
KEGGicje:Cj1292.
PATRICi20059548. VBICamJej33762_1274.

Phylogenomic databases

eggNOGiCOG0717.
HOGENOMiHOG000228600.
KOiK01494.
OMAiMEYFRIP.
OrthoDBiEOG67DPKR.

Enzyme and pathway databases

UniPathwayiUPA00610; UER00665.
BioCyciCJEJ192222:GJTS-1265-MONOMER.

Family and domain databases

Gene3Di2.70.40.10. 1 hit.
HAMAPiMF_00146. dCTP_deaminase.
InterProiIPR011962. dCTP_deam.
IPR029054. dUTPase-like.
IPR008180. dUTPase/dCTP_deaminase.
[Graphical view]
PfamiPF00692. dUTPase. 1 hit.
[Graphical view]
SUPFAMiSSF51283. SSF51283. 1 hit.
TIGRFAMsiTIGR02274. dCTP_deam. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NCTC 11168.

Entry informationi

Entry nameiDCD_CAMJE
AccessioniPrimary (citable) accession number: Q9PN07
Secondary accession number(s): Q0P8W5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 27, 2002
Last sequence update: October 1, 2000
Last modified: May 27, 2015
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.