SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9PMT4

- GLMS_CAMJE

UniProt

Q9PMT4 - GLMS_CAMJE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
Gene
glmS, Cj1366c
Organism
Campylobacter jejuni subsp. jejuni serotype O:2 (strain NCTC 11168)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source By similarity.UniRule annotation

Catalytic activityi

L-glutamine + D-fructose 6-phosphate = L-glutamate + D-glucosamine 6-phosphate.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei2 – 21Nucleophile; for GATase activity By similarity
Active sitei593 – 5931For Fru-6P isomerization activity By similarity

GO - Molecular functioni

  1. carbohydrate binding Source: InterPro
  2. glutamine-fructose-6-phosphate transaminase (isomerizing) activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbohydrate biosynthetic process Source: InterPro
  2. glutamine metabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminotransferase, Transferase

Enzyme and pathway databases

BioCyciCJEJ192222:GJTS-1339-MONOMER.

Protein family/group databases

MEROPSiC44.971.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] (EC:2.6.1.16)
Alternative name(s):
D-fructose-6-phosphate amidotransferase
GFAT
Glucosamine-6-phosphate synthase
Hexosephosphate aminotransferase
L-glutamine--D-fructose-6-phosphate amidotransferase
Gene namesi
Name:glmS
Ordered Locus Names:Cj1366c
OrganismiCampylobacter jejuni subsp. jejuni serotype O:2 (strain NCTC 11168)
Taxonomic identifieri192222 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter
ProteomesiUP000000799: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed By similarity
Chaini2 – 598597Glutamine--fructose-6-phosphate aminotransferase [isomerizing]UniRule annotation
PRO_0000135314Add
BLAST

Interactioni

Subunit structurei

Homodimer By similarity.UniRule annotation

Protein-protein interaction databases

IntActiQ9PMT4. 29 interactions.
STRINGi192222.Cj1366c.

Structurei

3D structure databases

ProteinModelPortaliQ9PMT4.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 218217Glutamine amidotransferase type-2
Add
BLAST
Domaini277 – 421145SIS 1
Add
BLAST
Domaini450 – 588139SIS 2
Add
BLAST

Sequence similaritiesi

Contains 2 SIS domains.

Keywords - Domaini

Glutamine amidotransferase, Repeat

Phylogenomic databases

eggNOGiCOG0449.
HOGENOMiHOG000258896.
KOiK00820.
OMAiSAGICTL.
OrthoDBiEOG6KT2Q1.

Family and domain databases

Gene3Di3.60.20.10. 1 hit.
HAMAPiMF_00164. GlmS.
InterProiIPR017932. GATase_2_dom.
IPR005855. GlmS_trans.
IPR029055. Ntn_hydrolases_N.
IPR001347. SIS.
[Graphical view]
PANTHERiPTHR10937:SF0. PTHR10937:SF0. 1 hit.
PfamiPF01380. SIS. 2 hits.
[Graphical view]
SUPFAMiSSF56235. SSF56235. 1 hit.
TIGRFAMsiTIGR01135. glmS. 1 hit.
PROSITEiPS51278. GATASE_TYPE_2. 1 hit.
PS51464. SIS. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9PMT4-1 [UniParc]FASTAAdd to Basket

« Hide

MCGIVGYIGN NEKKQIILNG LKELEYRGYD SAGMAVMQEG ELSFFKAVGK    50
LENLANKCTD FESQGYGFAI GHTRWATHGK PTEINAHPHL GQYSCVIHNG 100
IIENYKEIKD KLEKEGVSFL SQTDTEVIVQ LFEFYARNLG VFEAWQKTIK 150
ELRGAFATLL VTKKDPNHVY FAKNAAPLII GKNANKEWYF SSGDAPLIGS 200
CDEVMYLEDL SLGYASKDEL VVYENDILKS LCFSKLSGDK AYAKKDGFRF 250
FMEKEIYEQS RVMSEVLMGR IQGDEVVFDE LNNEDLSQVD EITLCACGTS 300
YHAAMASAYL FERIAKVKAK VEIASEFRYR EAIIKKDSLF IVISQSGETA 350
DTLEALKIAK EQGAKTFAIC NVDNSNIVRL AHLSLLTRAG IEKGVASTKA 400
FATQVLTLWM LAIFMAQKRN LNVSAEIKAL LHTPNCVSVK QALHEKIHRL 450
SKRYLDGHGF FFIGRDVFYP LALEGALKLK ELSYLHAEGY PAGEMKHGPI 500
ALADSKLYTI ALMPKHMLYE KTKSNVEELI ARDSTVLSIS PLEFDLSDDF 550
IKTNEQDHYM CEFFEMMVIT QLLAMEISIR LGNDVDMPRN LAKSVTVE 598
Length:598
Mass (Da):67,188
Last modified:January 23, 2007 - v3
Checksum:i9147183C44D594B2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL111168 Genomic DNA. Translation: CAL35478.1.
PIRiC81281.
RefSeqiYP_002344754.1. NC_002163.1.

Genome annotation databases

EnsemblBacteriaiCAL35478; CAL35478; Cj1366c.
GeneIDi905659.
KEGGicje:Cj1366c.
PATRICi20059697. VBICamJej33762_1347.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL111168 Genomic DNA. Translation: CAL35478.1 .
PIRi C81281.
RefSeqi YP_002344754.1. NC_002163.1.

3D structure databases

ProteinModelPortali Q9PMT4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi Q9PMT4. 29 interactions.
STRINGi 192222.Cj1366c.

Protein family/group databases

MEROPSi C44.971.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAL35478 ; CAL35478 ; Cj1366c .
GeneIDi 905659.
KEGGi cje:Cj1366c.
PATRICi 20059697. VBICamJej33762_1347.

Phylogenomic databases

eggNOGi COG0449.
HOGENOMi HOG000258896.
KOi K00820.
OMAi SAGICTL.
OrthoDBi EOG6KT2Q1.

Enzyme and pathway databases

BioCyci CJEJ192222:GJTS-1339-MONOMER.

Family and domain databases

Gene3Di 3.60.20.10. 1 hit.
HAMAPi MF_00164. GlmS.
InterProi IPR017932. GATase_2_dom.
IPR005855. GlmS_trans.
IPR029055. Ntn_hydrolases_N.
IPR001347. SIS.
[Graphical view ]
PANTHERi PTHR10937:SF0. PTHR10937:SF0. 1 hit.
Pfami PF01380. SIS. 2 hits.
[Graphical view ]
SUPFAMi SSF56235. SSF56235. 1 hit.
TIGRFAMsi TIGR01135. glmS. 1 hit.
PROSITEi PS51278. GATASE_TYPE_2. 1 hit.
PS51464. SIS. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NCTC 11168.

Entry informationi

Entry nameiGLMS_CAMJE
AccessioniPrimary (citable) accession number: Q9PMT4
Secondary accession number(s): Q0P8P3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 11, 2002
Last sequence update: January 23, 2007
Last modified: June 11, 2014
This is version 85 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi