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Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Campylobacter jejuni subsp. jejuni serotype O:2 (strain NCTC 11168)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei38 – 381SubstrateUniRule annotation
Binding sitei119 – 1191SubstrateUniRule annotation
Binding sitei152 – 1521SubstrateUniRule annotation
Binding sitei205 – 2051ATPUniRule annotation
Binding sitei296 – 2961ATP; via carbonyl oxygenUniRule annotation
Binding sitei327 – 3271ATPUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi353 – 3564ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCJEJ192222:GJTS-1372-MONOMER.
UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
Gene namesi
Name:pgkUniRule annotation
Ordered Locus Names:Cj1402c
OrganismiCampylobacter jejuni subsp. jejuni serotype O:2 (strain NCTC 11168)
Taxonomic identifieri192222 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter
ProteomesiUP000000799: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 400400Phosphoglycerate kinasePRO_0000145921Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

IntActiQ9PMQ5. 70 interactions.
STRINGi192222.Cj1402c.

Structurei

Secondary structure

1
400
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi7 – 93Combined sources
Beta strandi16 – 205Combined sources
Helixi37 – 5115Combined sources
Beta strandi55 – 595Combined sources
Helixi70 – 723Combined sources
Helixi75 – 8511Combined sources
Beta strandi93 – 975Combined sources
Helixi98 – 1069Combined sources
Beta strandi112 – 1143Combined sources
Helixi118 – 1203Combined sources
Helixi124 – 1263Combined sources
Helixi129 – 1379Combined sources
Beta strandi140 – 1445Combined sources
Helixi147 – 1493Combined sources
Turni155 – 1584Combined sources
Helixi159 – 1635Combined sources
Beta strandi168 – 1714Combined sources
Helixi173 – 18513Combined sources
Beta strandi191 – 1977Combined sources
Helixi202 – 21211Combined sources
Turni213 – 2153Combined sources
Beta strandi217 – 2215Combined sources
Helixi226 – 2327Combined sources
Helixi244 – 2463Combined sources
Helixi247 – 25913Combined sources
Beta strandi263 – 2653Combined sources
Beta strandi268 – 27710Combined sources
Beta strandi283 – 2864Combined sources
Helixi287 – 2893Combined sources
Beta strandi295 – 2995Combined sources
Helixi301 – 31111Combined sources
Beta strandi315 – 3217Combined sources
Helixi329 – 3313Combined sources
Helixi333 – 34412Combined sources
Beta strandi345 – 3539Combined sources
Helixi354 – 3629Combined sources
Helixi366 – 3683Combined sources
Beta strandi369 – 3724Combined sources
Helixi376 – 3838Combined sources
Helixi389 – 3924Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3Q3VX-ray2.14A/B1-400[»]
ProteinModelPortaliQ9PMQ5.
SMRiQ9PMQ5. Positions 4-398.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni22 – 243Substrate bindingUniRule annotation
Regioni61 – 644Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227107.
KOiK00927.
OMAiWEALDIG.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9PMQ5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSDIISIKDI DLAKKKVFIR CDFNVPQDDF LNITDDRRIR SAIPTIRYCL
60 70 80 90 100
DNGCSVILAS HLGRPKEISS KYSLEPVAKR LARLLDKEIV MAKDVIGEDA
110 120 130 140 150
KTKAMNLKAG EILLLENLRF EKGETKNDEN LAKELASMVQ VYINDAFGVC
160 170 180 190 200
HRAHSSVEAI TKFFDEKHKG AGFLLQKEID FASNLIKHPA RPFVAVVGGS
210 220 230 240 250
KVSGKLQALT NLLPKVDKLI IGGGMAFTFL KALGYDIGNS LLEEELLEEA
260 270 280 290 300
NKILTKGKNL GVKIYLPVDV VAAPACSQDV PMKFVPAQEI PNGWMGLDIG
310 320 330 340 350
PASVRLFKEV ISDAQTIWWN GPMGVFEIDK FSKGSIKMSH YISEGHATSV
360 370 380 390 400
VGGGDTADVV ARAGDADEMT FISTGGGASL ELIEGKELPG VKALRSKENE
Length:400
Mass (Da):43,591
Last modified:October 1, 2000 - v1
Checksum:i1DAB672AC4432BDF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL111168 Genomic DNA. Translation: CAL35511.1.
PIRiB81285.
RefSeqiYP_002344785.1. NC_002163.1.

Genome annotation databases

EnsemblBacteriaiCAL35511; CAL35511; Cj1402c.
GeneIDi905691.
KEGGicje:Cj1402c.
PATRICi20059770. VBICamJej33762_1383.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL111168 Genomic DNA. Translation: CAL35511.1.
PIRiB81285.
RefSeqiYP_002344785.1. NC_002163.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3Q3VX-ray2.14A/B1-400[»]
ProteinModelPortaliQ9PMQ5.
SMRiQ9PMQ5. Positions 4-398.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9PMQ5. 70 interactions.
STRINGi192222.Cj1402c.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAL35511; CAL35511; Cj1402c.
GeneIDi905691.
KEGGicje:Cj1402c.
PATRICi20059770. VBICamJej33762_1383.

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227107.
KOiK00927.
OMAiWEALDIG.
OrthoDBiEOG64N9Z0.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00185.
BioCyciCJEJ192222:GJTS-1372-MONOMER.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NCTC 11168.

Entry informationi

Entry nameiPGK_CAMJE
AccessioniPrimary (citable) accession number: Q9PMQ5
Secondary accession number(s): Q0P8L2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 27, 2002
Last sequence update: October 1, 2000
Last modified: January 7, 2015
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.