Reviewed, UniProtKB/Swiss-Prot Q9PMQ5 (PGK_CAMJE)

Names and origin

Protein names

Recommended name:
    Phosphoglycerate kinase
    EC=2.7.2.3

Gene names

Name:	pgk
Ordered Locus Names:	Cj1402c

Organism

Campylobacter jejuni [Complete proteome] [HAMAP]

Taxonomic identifier

197 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length	400 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Catalytic activity	ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP MF_00145
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP MF_00145
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
Biological process	Glycolysis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoglycerate kinase activity Inferred from electronic annotation. Source: HAMAP protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
flgI	Q9PMJ8	1	EBI-1194114,EBI-1191749
fliG	Q0PBJ0	1	EBI-1194114,EBI-1191336

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 400	400	Phosphoglycerate kinase HAMAP MF_00145		PRO_0000145921
Regions
	Nucleotide binding	353 – 356	4	ATP By similarity
	Region	22 – 24	3	Substrate binding By similarity
	Region	61 – 64	4	Substrate binding By similarity
Sites
	Binding site	38	1	Substrate By similarity
	Binding site	119	1	Substrate By similarity
	Binding site	152	1	Substrate By similarity
	Binding site	205	1	ATP By similarity
	Binding site	296	1	ATP; via carbonyl oxygen By similarity
	Binding site	327	1	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9PMQ5-1 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 1DAB672AC4432BDF	FASTA	400	43,591
	10 20 30 40 50 60 MSDIISIKDI DLAKKKVFIR CDFNVPQDDF LNITDDRRIR SAIPTIRYCL DNGCSVILAS 70 80 90 100 110 120 HLGRPKEISS KYSLEPVAKR LARLLDKEIV MAKDVIGEDA KTKAMNLKAG EILLLENLRF 130 140 150 160 170 180 EKGETKNDEN LAKELASMVQ VYINDAFGVC HRAHSSVEAI TKFFDEKHKG AGFLLQKEID 190 200 210 220 230 240 FASNLIKHPA RPFVAVVGGS KVSGKLQALT NLLPKVDKLI IGGGMAFTFL KALGYDIGNS 250 260 270 280 290 300 LLEEELLEEA NKILTKGKNL GVKIYLPVDV VAAPACSQDV PMKFVPAQEI PNGWMGLDIG 310 320 330 340 350 360 PASVRLFKEV ISDAQTIWWN GPMGVFEIDK FSKGSIKMSH YISEGHATSV VGGGDTADVV 370 380 390 400 ARAGDADEMT FISTGGGASL ELIEGKELPG VKALRSKENE

References

[1]

"The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences." Parkhill J., Wren B.W., Mungall K.L., Ketley J.M., Churcher C.M., Basham D., Chillingworth T., Davies R.M., Feltwell T., Holroyd S., Jagels K., Karlyshev A.V., Moule S., Pallen M.J., Penn C.W., Quail M.A., Rajandream M.A., Rutherford K.M. , van Vliet A.H.M., Whitehead S., Barrell B.G. Nature 403:665-668(2000) [PubMed: 10688204] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NCTC 11168 / Serotype O:2.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL111168 Genomic DNA. Translation: CAL35511.1.
PIR	B81285.
RefSeq	YP_002344785.1.
3D structure databases
HSSP	HSSP built from PDB template 1VPE based on UniProtKB P36204.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9PMQ5. 72 interactions.
Genome annotation databases
GeneID	905691.
GenomeReviews	Gene locus Cj1402c in contig AL111168_GR.
KEGG	cje:Cj1402c.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	Q9PMQ5. CLENTRF.
Enzyme and pathway databases
BioCyc	CJEJ192222:CJ1402C-MON.
BRENDA	2.7.2.3. 255835.
Family and domain databases
HAMAP	MF_00145. [Tree]
InterPro	IPR001576. Phosphoglycerate_kinase. IPR015901. Phosphoglycerate_kinase_C. IPR015911. Phosphoglycerate_kinase_CS. IPR015824. Phosphoglycerate_kinase_N. [Graphical view]
Gene3D	G3DSA:3.40.50.1270. Phosphoglycerate_kinase_C. 1 hit. G3DSA:3.40.50.1260. Phosphoglycerate_kinase_N. 1 hit.
PANTHER	PTHR11406. PGK. 1 hit.
Pfam	PF00162. PGK. 1 hit. [Graphical view]
PRINTS	PR00477. PHGLYCKINASE.
PROSITE	PS00111. PGLYCERATE_KINASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PGK_CAMJE

Accession

Primary (citable) accession number: Q9PMQ5
Secondary accession number(s): Q0P8L2

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 27, 2002
Last sequence update:	October 1, 2000
Last modified:	June 16, 2009
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)