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Q9PMQ5 (PGK_CAMJE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase
EC=2.7.2.3
Gene names
Name:pgk
Ordered Locus Names:Cj1402c
OrganismCampylobacter jejuni subsp. jejuni serotype O:2 (strain NCTC 11168) [Reference proteome] [HAMAP]
Taxonomic identifier192222 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter ›

Protein attributes

Sequence length400 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Binary interactions

With

Entry

#Exp.

IntAct

Notes

flgIQ9PMJ81EBI-1194114,EBI-1191749
fliGQ0PBJ01EBI-1194114,EBI-1191336

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 400400Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_0000145921

Regions

Nucleotide binding353 – 3564ATP By similarity
Region22 – 243Substrate binding By similarity
Region61 – 644Substrate binding By similarity

Sites

Binding site381Substrate By similarity
Binding site1191Substrate By similarity
Binding site1521Substrate By similarity
Binding site2051ATP By similarity
Binding site2961ATP; via carbonyl oxygen By similarity
Binding site3271ATP By similarity

Secondary structure

1 ......................................................................... 400
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q9PMQ5 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 1DAB672AC4432BDF

FASTA40043,591
        10         20         30         40         50         60 
MSDIISIKDI DLAKKKVFIR CDFNVPQDDF LNITDDRRIR SAIPTIRYCL DNGCSVILAS 

        70         80         90        100        110        120 
HLGRPKEISS KYSLEPVAKR LARLLDKEIV MAKDVIGEDA KTKAMNLKAG EILLLENLRF 

       130        140        150        160        170        180 
EKGETKNDEN LAKELASMVQ VYINDAFGVC HRAHSSVEAI TKFFDEKHKG AGFLLQKEID 

       190        200        210        220        230        240 
FASNLIKHPA RPFVAVVGGS KVSGKLQALT NLLPKVDKLI IGGGMAFTFL KALGYDIGNS 

       250        260        270        280        290        300 
LLEEELLEEA NKILTKGKNL GVKIYLPVDV VAAPACSQDV PMKFVPAQEI PNGWMGLDIG 

       310        320        330        340        350        360 
PASVRLFKEV ISDAQTIWWN GPMGVFEIDK FSKGSIKMSH YISEGHATSV VGGGDTADVV 

       370        380        390        400 
ARAGDADEMT FISTGGGASL ELIEGKELPG VKALRSKENE

« Hide

References

[1]"The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences."
Parkhill J., Wren B.W., Mungall K.L., Ketley J.M., Churcher C.M., Basham D., Chillingworth T., Davies R.M., Feltwell T., Holroyd S., Jagels K., Karlyshev A.V., Moule S., Pallen M.J., Penn C.W., Quail M.A., Rajandream M.A., Rutherford K.M. expand/collapse author list , van Vliet A.H.M., Whitehead S., Barrell B.G.
Nature 403:665-668(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NCTC 11168.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AL111168 Genomic DNA. Translation: CAL35511.1.
PIRB81285.
RefSeqYP_002344785.1. NC_002163.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3Q3VX-ray2.14A/B1-400[»]
ProteinModelPortalQ9PMQ5.
SMRQ9PMQ5. Positions 4-398.
ModBaseSearch...

Protein-protein interaction databases

IntActQ9PMQ5. 70 interactions.
STRING192222.Cj1402c.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAL35511; CAL35511; Cj1402c.
GeneID905691.
KEGGcje:Cj1402c.
PATRIC20059770. VBICamJej33762_1383.

Phylogenomic databases

eggNOGCOG0126.
HOGENOMHOG000227107.
KOK00927.
OMAKFGLADK.
ProtClustDBPRK00073.

Enzyme and pathway databases

BioCycCJEJ192222:GJTS-1372-MONOMER.
UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. PGK. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_CAMJE
AccessionPrimary (citable) accession number: Q9PMQ5
Secondary accession number(s): Q0P8L2
Entry history
Integrated into UniProtKB/Swiss-Prot: May 27, 2002
Last sequence update: October 1, 2000
Last modified: May 1, 2013
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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