Reviewed, UniProtKB/Swiss-Prot Q9PMF9 (SELD_CAMJE)

Names and origin

Protein names

Recommended name:
    Selenide, water dikinase
    EC=2.7.9.3
Alternative name(s):
    Selenophosphate synthetase
    Selenium donor protein

Gene names

Name:	selD
Ordered Locus Names:	Cj1504c

Organism

Campylobacter jejuni [Complete proteome] [HAMAP]

Taxonomic identifier

197 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length	340 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Synthesizes selenophosphate from selenide and ATP By similarity.
Catalytic activity	ATP + selenide + H2O = AMP + selenophosphate + phosphate. HAMAP MF_00625
Cofactor	Magnesium By similarity.
Sequence similarities	Belongs to the selenophosphate synthetase 1 family. Class I subfamily.
Sequence caution	The sequence CAL35610.1 differs from that shown. Reason: Erroneous termination at position 17. Translated as Sec.

Ontologies

Keywords
Coding sequence diversity	Selenocysteine
Ligand	ATP-binding Magnesium Nucleotide-binding Selenium
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: HAMAP selenide, water dikinase activity Inferred from electronic annotation. Source: HAMAP selenium binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 340	340	Selenide, water dikinase HAMAP MF_00625		PRO_0000127618
Regions
	Nucleotide binding	227 – 233	7	ATP Potential
Sites
	Active site	17	1	Potential
	Site	20	1	Important for catalytic activity By similarity
Amino acid modifications
	Non-standard residue	17	1	Selenocysteine Potential

Sequences

	Sequence		Length	Mass (Da)
	Q9PMF9-1 [UniParc]. Last modified February 26, 2008. Version 3. Checksum: FA4DE2CAE618E430	FASTA	340	37,077
	10 20 30 40 50 60 MQYKNQNLTH FVKAAGUAAK LSPGGLKTIL NFMQKTPALL SDIGNNEDAS VYQISPDLAL 70 80 90 100 110 120 VQTLDFITPI VDSAYHFGAI AAANALSDVF AMGAEVINAL NIVGFDTCNH DLNILKELLE 130 140 150 160 170 180 GANDKVKECN ALVVGGHTIE STELFFGLSV TGKVHPSKFI ANNTSKIGDC IILTKPLGTG 190 200 210 220 230 240 ILSTALKAQM LNQKHLDIML KNMIELNYKA SQIALKFHPS AMSDVTGFGL LGHLKEMLNK 250 260 270 280 290 300 NISFEIFESE LPFLDGVKEY FNMGLIPAGA YKNLEFIKEL TPDLNEEKLL LCDPQTSGGL 310 320 330 340 LISISEKDSL ECLKKLEDEN IQAKIIAKVV NKQENDIIIS

References

[1]

"The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences." Parkhill J., Wren B.W., Mungall K.L., Ketley J.M., Churcher C.M., Basham D., Chillingworth T., Davies R.M., Feltwell T., Holroyd S., Jagels K., Karlyshev A.V., Moule S., Pallen M.J., Penn C.W., Quail M.A., Rajandream M.A., Rutherford K.M. , van Vliet A.H.M., Whitehead S., Barrell B.G. Nature 403:665-668(2000) [PubMed: 10688204] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NCTC 11168 / Serotype O:2.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL111168 Genomic DNA. Translation: CAL35610.1. Sequence problems.
PIR	D81297.
RefSeq	YP_002344883.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	905797.
GenomeReviews	Gene locus Cj1504c in contig AL111168_GR.
KEGG	cje:Cj1504c.
Organism-specific databases
CMR	Search...
Enzyme and pathway databases
BioCyc	CJEJ192222:CJ1504C-MON.
BRENDA	2.7.9.3. 255835.
Family and domain databases
HAMAP	MF_00625. [Tree]
InterPro	IPR000728. AIR_synth. IPR010918. AIR_synth_C. IPR004536. SelD. [Graphical view]
Pfam	PF00586. AIRS. 1 hit. PF02769. AIRS_C. 1 hit. [Graphical view]
PIRSF	PIRSF036407. Selenphspht_syn. 1 hit.
TIGRFAMs	TIGR00476. selD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SELD_CAMJE

Accession

Primary (citable) accession number: Q9PMF9
Secondary accession number(s): Q0P8B4

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 25, 2003
Last sequence update:	February 26, 2008
Last modified:	March 24, 2009
This is version 47 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)