Q9PMD9 (COAE_CAMJE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Dephospho-CoA kinase
EC=2.7.1.24

Alternative name(s):
Dephosphocoenzyme A kinase

Gene names

Name:	coaE
Ordered Locus Names:	Cj1530

Organism

Campylobacter jejuni

Taxonomic identifier

197 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length	201 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A By similarity. HAMAP MF_00376
Catalytic activity	ATP + 3'-dephospho-CoA = ADP + CoA. HAMAP MF_00376
Pathway	Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 5/5. HAMAP MF_00376
Subcellular location	Cytoplasm By similarity HAMAP MF_00376.
Sequence similarities	Belongs to the CoaE family. Contains 1 DPCK (dephospho-CoA kinase) domain.

Ontologies

Keywords
Biological process	Coenzyme A biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	coenzyme A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW dephospho-CoA kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 201	201	Dephospho-CoA kinase HAMAP MF_00376		PRO_0000172922
Regions
	Domain	4 – 201	198	DPCK
	Nucleotide binding	9 – 16	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q9PMD9 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 532D6B6C821B2608	FASTA	201	23,048
	10 20 30 40 50 60 MKNAFFVTAS IACGKSTFIE IANSLGFKSI SADKIAHKIL DENALELEKI FSPFSLKNLL 70 80 90 100 110 120 KKEKKIDRKI LGEIVFNNKE AKKILENFTH PKIRAKILEQ MQILDKENKA FFVEIPLFFE 130 140 150 160 170 180 SGAYENLGKV IVIYTPKELS LKRIMQRDKL SLEAAKARLD SQIDIEEKLK KADFIIKNTN 190 200 SYADFRQECV KVIQEISKGN M

References

[1]

"The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences." Parkhill J., Wren B.W., Mungall K.L., Ketley J.M., Churcher C.M., Basham D., Chillingworth T., Davies R.M., Feltwell T., Holroyd S., Jagels K., Karlyshev A.V., Moule S., Pallen M.J., Penn C.W., Quail M.A., Rajandream M.A., Rutherford K.M. , van Vliet A.H.M., Whitehead S., Barrell B.G. Nature 403:665-668(2000) [PubMed: 10688204] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NCTC 11168 / Serotype O:2.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL111168 Genomic DNA. Translation: CAL35630.1.
PIR	H81299.
RefSeq	YP_002344902.1. NC_002163.1.
3D structure databases
ProteinModelPortal	Q9PMD9.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9PMD9. 2 interactions.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	905813.
GenomeReviews	Gene locus Cj1530 in contig AL111168_GR.
KEGG	cje:Cj1530.
PATRIC	20060020. VBICamJej33762_1507.
Phylogenomic databases
HOGENOM	HBG650290.
OMA	CELFEAD.
ProtClustDB	PRK00081.
Enzyme and pathway databases
BioCyc	CJEJ192222:CJ1530-MONOMER.
Family and domain databases
HAMAP	MF_00376. Dephospho_CoA_kinase. [Tree]
InterPro	IPR001977. Depp_CoAkinase. [Graphical view]
KO	K00859.
Pfam	PF01121. CoaE. 1 hit. [Graphical view]
TIGRFAMs	TIGR00152. TIGR00152. 1 hit.
PROSITE	PS51219. DPCK. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

COAE_CAMJE

Accession

Primary (citable) accession number: Q9PMD9
Secondary accession number(s): Q0P895

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 1, 2001
Last sequence update:	October 1, 2000
Last modified:	January 25, 2012
This is version 71 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program