Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q9PMD4 (G6PI_CAMJE) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:Cj1535c
OrganismCampylobacter jejuni subsp. jejuni serotype O:2 (strain NCTC 11168) [Reference proteome] [HAMAP]
Taxonomic identifier192222 [NCBI]
Taxonomic lineageBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter

Protein attributes

Sequence length406 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 406406Probable glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180616

Sites

Active site2591Proton donor By similarity
Active site2841 By similarity
Active site3971 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9PMD4 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: F5BD432A86E482CE

FASTA40646,013
        10         20         30         40         50         60 
MLNNTLFFKQ SEIHTISSYA NRINDEVKSG DIGYYHLIDT SLNLIDESLQ FIQDKEYVKN 

        70         80         90        100        110        120 
IVLVGMGGSS CGVKALRDML FNEKSNQREL FILDNTSSHS FNKTLEKIKL EESLFLIISK 

       130        140        150        160        170        180 
TGSTIEVVSL FKLLIEHFKL DMQELKKYFV FITDKDSKLH QEGENLGIKC FFIPANVGGR 

       190        200        210        220        230        240 
FSILSAVGIV PLCFCGYNAK ALLEGAKACF EDFFTHKKDE ILQKAYHYCT HKNANINVLF 

       250        260        270        280        290        300 
SYSDAFKGFN EWYIQLIAES LGKKQGYKRI GLTPIALIGA RDQHSFLQLI MDGPKNKTVT 

       310        320        330        340        350        360 
FLKIKDAQKA PIIPDIHFKF LDSLSNKVNL HELLNAQCDA TMHALIAENL SVDVIELEKL 

       370        380        390        400 
DAWHAGYLMY YYELFTSTCG VMLGINTYDQ PGVEVGKLIL KNILNS 

« Hide

References

[1]"The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences."
Parkhill J., Wren B.W., Mungall K.L., Ketley J.M., Churcher C.M., Basham D., Chillingworth T., Davies R.M., Feltwell T., Holroyd S., Jagels K., Karlyshev A.V., Moule S., Pallen M.J., Penn C.W., Quail M.A., Rajandream M.A., Rutherford K.M. expand/collapse author list , van Vliet A.H.M., Whitehead S., Barrell B.G.
Nature 403:665-668(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NCTC 11168.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL111168 Genomic DNA. Translation: CAL35635.1.
PIRE81300.
RefSeqYP_002344907.1. NC_002163.1.

3D structure databases

ProteinModelPortalQ9PMD4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActQ9PMD4. 47 interactions.
STRING192222.Cj1535c.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAL35635; CAL35635; Cj1535c.
GeneID905817.
KEGGcje:Cj1535c.
PATRIC20060030. VBICamJej33762_1512.

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000100402.
KOK01810.
OMADWYRQLW.
OrthoDBEOG64R61J.
ProtClustDBPRK03868.

Enzyme and pathway databases

BioCycCJEJ192222:GJTS-1497-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_CAMJE
AccessionPrimary (citable) accession number: Q9PMD4
Secondary accession number(s): Q0P890
Entry history
Integrated into UniProtKB/Swiss-Prot: November 2, 2001
Last sequence update: October 1, 2000
Last modified: February 19, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways