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Protein

Probable glucose-6-phosphate isomerase

Gene

pgi

Organism
Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Probable glucose-6-phosphate isomerase (pgi)
  3. no protein annotated in this organism
  4. Fructose-bisphosphate aldolase (fba)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei259Proton donorBy similarity1
Active sitei284By similarity1
Active sitei397By similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processGluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciCJEJ192222:G1G1F-1491-MONOMER
UniPathwayiUPA00109; UER00181

Names & Taxonomyi

Protein namesi
Recommended name:
Probable glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:Cj1535c
OrganismiCampylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
Taxonomic identifieri192222 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter
Proteomesi
  • UP000000799 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001806161 – 406Probable glucose-6-phosphate isomeraseAdd BLAST406

Proteomic databases

PaxDbiQ9PMD4

Interactioni

Protein-protein interaction databases

IntActiQ9PMD4, 47 interactors
STRINGi192222.Cj1535c

Structurei

3D structure databases

ProteinModelPortaliQ9PMD4
SMRiQ9PMD4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.Curated

Phylogenomic databases

eggNOGiENOG4107QP8 Bacteria
COG0166 LUCA
HOGENOMiHOG000100402
KOiK01810
OMAiSFIIPDD

Family and domain databases

CDDicd05015 SIS_PGI_1, 1 hit
cd05016 SIS_PGI_2, 1 hit
HAMAPiMF_00473 G6P_isomerase, 1 hit
InterProiView protein in InterPro
IPR001672 G6P_Isomerase
IPR018189 Phosphoglucose_isomerase_CS
IPR035476 SIS_PGI_1
IPR035482 SIS_PGI_2
PANTHERiPTHR11469 PTHR11469, 1 hit
PfamiView protein in Pfam
PF00342 PGI, 1 hit
PRINTSiPR00662 G6PISOMERASE
PROSITEiView protein in PROSITE
PS00765 P_GLUCOSE_ISOMERASE_1, 1 hit
PS00174 P_GLUCOSE_ISOMERASE_2, 1 hit
PS51463 P_GLUCOSE_ISOMERASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q9PMD4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLNNTLFFKQ SEIHTISSYA NRINDEVKSG DIGYYHLIDT SLNLIDESLQ
60 70 80 90 100
FIQDKEYVKN IVLVGMGGSS CGVKALRDML FNEKSNQREL FILDNTSSHS
110 120 130 140 150
FNKTLEKIKL EESLFLIISK TGSTIEVVSL FKLLIEHFKL DMQELKKYFV
160 170 180 190 200
FITDKDSKLH QEGENLGIKC FFIPANVGGR FSILSAVGIV PLCFCGYNAK
210 220 230 240 250
ALLEGAKACF EDFFTHKKDE ILQKAYHYCT HKNANINVLF SYSDAFKGFN
260 270 280 290 300
EWYIQLIAES LGKKQGYKRI GLTPIALIGA RDQHSFLQLI MDGPKNKTVT
310 320 330 340 350
FLKIKDAQKA PIIPDIHFKF LDSLSNKVNL HELLNAQCDA TMHALIAENL
360 370 380 390 400
SVDVIELEKL DAWHAGYLMY YYELFTSTCG VMLGINTYDQ PGVEVGKLIL

KNILNS
Length:406
Mass (Da):46,013
Last modified:October 1, 2000 - v1
Checksum:iF5BD432A86E482CE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL111168 Genomic DNA Translation: CAL35635.1
PIRiE81300
RefSeqiWP_002855462.1, NC_002163.1
YP_002344907.1, NC_002163.1

Genome annotation databases

EnsemblBacteriaiCAL35635; CAL35635; Cj1535c
GeneIDi905817
KEGGicje:Cj1535c
PATRICifig|192222.6.peg.1512

Similar proteinsi

Entry informationi

Entry nameiG6PI_CAMJE
AccessioniPrimary (citable) accession number: Q9PMD4
Secondary accession number(s): Q0P890
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 2, 2001
Last sequence update: October 1, 2000
Last modified: February 28, 2018
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health