Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q9PM41 (AROC_CAMJE) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Chorismate synthase
EC=4.2.3.5
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate phospholyase
Gene names
Name:aroC
Ordered Locus Names:Cj1634c
OrganismCampylobacter jejuni
Taxonomic identifier197 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length362 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300

Cofactor

Reduced flavin By similarity. HAMAP MF_00300

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300

Subunit structure

Homotetramer By similarity. HAMAP MF_00300

Sequence similarities

Belongs to the chorismate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Molecular functionLyase
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionchorismate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 362362Chorismate synthase HAMAP MF_00300
PRO_0000140568

Secondary structure

1 ..................................................... 362
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q9PM41 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 7A9EDAE23F59AA75

FASTA36239,252
        10         20         30         40         50         60 
MNTFGTRLKF TSFGESHGVA VGCIIDGMPA GVKFDEEFLQ NELDKRKGGS KFATPRKESD 

        70         80         90        100        110        120 
KAQVLSGVFE GYTTGHPIAI VVFNENAHSK DYDNLKDLFR PAHADFTYFY KYGIRDHRGG 

       130        140        150        160        170        180 
GRSSARESVA RVAGGAVAAM LLREFDICVQ SGVFGVGTFV SNLKEEEFDF EFAKKSEIFC 

       190        200        210        220        230        240 
LDPKLESDFK NEILNARNSK DSVGAAVFTK VSGMLIGLGE VLYDKLDSKL AHALMGINAV 

       250        260        270        280        290        300 
KAVEIGEGIN ASKMRGSCNN DALKDGKFLS NHSGGILGGI SNGENLILKT YFKPTPSIFA 

       310        320        330        340        350        360 
KQESIDKFGN NLKFELKGRH DPCVGVRGSV VASAMVRLVL ADCLLLNASA NLNNLKNAYG 


LK

« Hide

References

[1]"The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences."
Parkhill J., Wren B.W., Mungall K.L., Ketley J.M., Churcher C.M., Basham D., Chillingworth T., Davies R.M., Feltwell T., Holroyd S., Jagels K., Karlyshev A.V., Moule S., Pallen M.J., Penn C.W., Quail M.A., Rajandream M.A., Rutherford K.M. expand/collapse author list , van Vliet A.H.M., Whitehead S., Barrell B.G.
Nature 403:665-668(2000) [PubMed: 10688204] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NCTC 11168 / Serotype O:2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AL111168 Genomic DNA. Translation: CAL35731.1.
PIRH81259.
RefSeqYP_002345003.1. NC_002163.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1SQ1X-ray2.80A1-362[»]
ProteinModelPortalQ9PM41.
SMRQ9PM41. Positions 1-360.
ModBaseSearch...

Protein-protein interaction databases

IntActQ9PM41. 92 interactions.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID905907.
GenomeReviewsGene locus Cj1634c in contig AL111168_GR.
KEGGcje:Cj1634c.
PATRIC20060236. VBICamJej33762_1610.

Phylogenomic databases

HOGENOMHBG292336.
OMAGVQGGIS.
ProtClustDBPRK05382.

Enzyme and pathway databases

BioCycCJEJ192222:CJ1634C-MONOMER.

Family and domain databases

HAMAPMF_00300. Chorismate_synth.
[Tree]
InterProIPR000453. Chorismate_synth.
IPR020541. Chorismate_synthase_CS.
[Graphical view]
KOK01736.
PANTHERPTHR21085. Chorismate_synth. 1 hit.
PfamPF01264. Chorismate_synt. 1 hit.
[Graphical view]
PIRSFPIRSF001456. Chorismate_synth. 1 hit.
SUPFAMSSF103263. Chorismate_synth. 1 hit.
TIGRFAMsTIGR00033. AroC. 1 hit.
PROSITEPS00787. CHORISMATE_SYNTHASE_1. 1 hit.
PS00788. CHORISMATE_SYNTHASE_2. 1 hit.
PS00789. CHORISMATE_SYNTHASE_3. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROC_CAMJE
AccessionPrimary (citable) accession number: Q9PM41
Secondary accession number(s): Q0P7Z4
Entry history
Integrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: October 1, 2000
Last modified: January 25, 2012
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents