Reviewed, UniProtKB/Swiss-Prot Q9PM24 (MURI_CAMJE)

Names and origin

Protein names

Recommended name:
    Glutamate racemase
    EC=5.1.1.3

Gene names

Name:	murI
Ordered Locus Names:	Cj1652c

Organism

Campylobacter jejuni [Complete proteome] [HAMAP]

Taxonomic identifier

197 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length	250 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Provides the (R)-glutamate required for cell wall biosynthesis By similarity. HAMAP MF_00258
Catalytic activity	L-glutamate = D-glutamate. HAMAP MF_00258
Pathway	Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00258
Sequence similarities	Belongs to the aspartate/glutamate racemases family.

Ontologies

Keywords
Biological process	Cell shape Cell wall biogenesis/degradation Peptidoglycan synthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cellular cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan biosynthetic process Inferred from electronic annotation. Source: HAMAP regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	glutamate racemase activity Inferred from electronic annotation. Source: HAMAP protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
flaG	Q0PAW9	1	EBI-1328097,EBI-1191365

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 250	250	Glutamate racemase HAMAP MF_00258		PRO_0000095462

Sequences

	Sequence		Length	Mass (Da)
	Q9PM24-1 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 6F0CE3981E24DE5F	FASTA	250	28,084
	10 20 30 40 50 60 MKIGVFDSGV GGLSVLKSLY EARLFDEIIY YGDTARVPYG VKDKDTIIKF CLEALDFFEQ 70 80 90 100 110 120 FQIDMLIIAC NTASAYALDA LRAKAHFPVY GVIDAGVEAT IKALHDKNKE ILVIATKATI 130 140 150 160 170 180 KSEEYQKRLL SQGYTNINAL ATGLFVPMVE EGIFEGDFLQ SAMEYYFKNI TTPDALILAC 190 200 210 220 230 240 THFPLLGRSL SKYFGDKTKL IHSGDAIVEF LKERENIDLK NHKAKLHFYA SSDVESLKNT 250 AKIWLNLLRK

References

[1]

"The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences." Parkhill J., Wren B.W., Mungall K.L., Ketley J.M., Churcher C.M., Basham D., Chillingworth T., Davies R.M., Feltwell T., Holroyd S., Jagels K., Karlyshev A.V., Moule S., Pallen M.J., Penn C.W., Quail M.A., Rajandream M.A., Rutherford K.M. , van Vliet A.H.M., Whitehead S., Barrell B.G. Nature 403:665-668(2000) [PubMed: 10688204] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NCTC 11168 / Serotype O:2.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL111168 Genomic DNA. Translation: CAL35749.1.
PIR	B81262.
RefSeq	YP_002345021.1.
3D structure databases
SMR	Q9PM24. Positions 1-247.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9PM24. 20 interactions.
Genome annotation databases
GeneID	905925.
GenomeReviews	Gene locus Cj1652c in contig AL111168_GR.
KEGG	cje:Cj1652c.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG645102.
OMA	NSPPREV.
Enzyme and pathway databases
BioCyc	CJEJ192222:CJ1652C-MONOMER.
BRENDA	5.1.1.3. 255835.
Family and domain databases
HAMAP	MF_00258. Glu_racemase. [Tree]
InterPro	IPR015942. Asp/Glu/hydantoin_racemase. IPR001920. Asp/Glu_race. IPR018187. Asp/Glu_racemase_AS. IPR004391. Glu_race. [Graphical view]
Gene3D	G3DSA:3.40.50.1860. Asp/Glu_race. 1 hit.
Pfam	PF01177. Asp_Glu_race. 1 hit. [Graphical view]
TIGRFAMs	TIGR00067. glut_race. 1 hit.
PROSITE	PS00923. ASP_GLU_RACEMASE_1. 1 hit. PS00924. ASP_GLU_RACEMASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MURI_CAMJE

Accession

Primary (citable) accession number: Q9PM24
Secondary accession number(s): Q0P7X6

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	October 1, 2000
Last modified:	February 9, 2010
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)