Reviewed,
UniProtKB/Swiss-Prot Q9PLG5 (MURD_CHLMU)
Last modified
June 16, 2009.
Version 58.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: UDP-N-acetylmuramoylalanine--D-glutamate ligase EC=6.3.2.9 Alternative name(s): UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase D-glutamic acid-adding enzyme | ||||
| Gene names |
| ||||
| Organism | Chlamydia muridarum [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 83560 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydia |
Protein attributes
| Sequence length | 416 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) By similarity. |
| Catalytic activity | ATP + UDP-N-acetylmuramoyl-L-alanine + glutamate = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate. HAMAP MF_00639 |
| Pathway | Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00639 |
| Subcellular location | Cytoplasm By similarity. |
| Sequence similarities | Belongs to the murCDEF family. |
Ontologies
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 416 | 416 | UDP-N-acetylmuramoylalanine--D-glutamate ligase HAMAP MF_00639 | PRO_0000108992 | |||||
Regions | |||||||||
| Nucleotide binding | 108 – 114 | 7 | ATP Potential | ||||||
Sequences
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References
| [1] | "Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae AR39." Read T.D., Brunham R.C., Shen C., Gill S.R., Heidelberg J.F., White O., Hickey E.K., Peterson J.D., Utterback T.R., Berry K.J., Bass S., Linher K.D., Weidman J.F., Khouri H.M., Craven B., Bowman C., Dodson R.J., Gwinn M.L. Fraser C.M.Nucleic Acids Res. 28:1397-1406(2000) [PubMed: 10684935] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MoPn / Nigg. |
Cross-references
Sequence databases | |
|---|---|
| AE002160 Genomic DNA. Translation: AAF39017.1. Different initiation. | |
| PIR | F81736. |
| RefSeq | NP_296518.1. |
3D structure databases | |
| HSSP | HSSP built from PDB template 1EEH based on UniProtKB P14900. |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 1245673. |
| GenomeReviews | Gene locus TC_0139 in contig AE002160_GR. |
| KEGG | cmu:TC0139. |
| TIGR | TC_0139. |
Phylogenomic databases | |
| HOGENOM | Q9PLG5. |
Enzyme and pathway databases | |
| BioCyc | CMUR243161:TC_0139-MON. |
| BRENDA | 6.3.2.9. 256349. |
Family and domain databases | |
| HAMAP | MF_00639. [Tree] |
| InterPro | IPR004101. Mur_ligase_C. IPR013221. Mur_ligase_cen. IPR016040. NAD(P)-bd_dom. IPR003099. Prephen_DH. IPR005762. UDP-N-AcMur-Glu_ligase. [Graphical view] |
| Gene3D | G3DSA:3.90.190.20. Mur_ligase_C. 1 hit. G3DSA:3.40.1190.10. Mur_ligase_cen. 1 hit. G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. |
| Pfam | PF02875. Mur_ligase_C. 1 hit. PF08245. Mur_ligase_M. 1 hit. PF02153. PDH. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR01087. murD. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | MURD_CHLMU | ||||||||
| Accession | Primary (citable) accession number: Q9PLG5 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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